BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

233 related articles for article (PubMed ID: 14609321)

  • 1. High-resolution structure of the Yersinia pestis protein tyrosine phosphatase YopH in complex with a phosphotyrosyl mimetic-containing hexapeptide.
    Phan J; Lee K; Cherry S; Tropea JE; Burke TR; Waugh DS
    Biochemistry; 2003 Nov; 42(45):13113-21. PubMed ID: 14609321
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis of tripeptides as potent Yersinia protein tyrosine phosphatase inhibitors.
    Lee K; Boovanahalli SK; Nam KY; Kang SU; Lee M; Phan J; Wu L; Waugh DS; Zhang ZY; No KT; Lee JJ; Burke TR
    Bioorg Med Chem Lett; 2005 Sep; 15(18):4037-42. PubMed ID: 16039123
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Two substrate-targeting sites in the Yersinia protein tyrosine phosphatase co-operate to promote bacterial virulence.
    Ivanov MI; Stuckey JA; Schubert HL; Saper MA; Bliska JB
    Mol Microbiol; 2005 Mar; 55(5):1346-56. PubMed ID: 15720545
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure of the N-terminal domain of Yersinia pestis YopH at 2.0 A resolution.
    Evdokimov AG; Tropea JE; Routzahn KM; Copeland TD; Waugh DS
    Acta Crystallogr D Biol Crystallogr; 2001 Jun; 57(Pt 6):793-9. PubMed ID: 11375498
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Computational analysis of tyrosine phosphatase inhibitor selectivity for the virulence factors YopH and SptP.
    Hu X; Vujanac M; Stebbins CE
    J Mol Graph Model; 2004 Oct; 23(2):175-87. PubMed ID: 15363459
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A focused library of protein tyrosine phosphatase inhibitors.
    Comeau AB; Critton DA; Page R; Seto CT
    J Med Chem; 2010 Sep; 53(18):6768-72. PubMed ID: 20731359
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Crystal structure of the Yersinia protein-tyrosine phosphatase YopH complexed with a specific small molecule inhibitor.
    Sun JP; Wu L; Fedorov AA; Almo SC; Zhang ZY
    J Biol Chem; 2003 Aug; 278(35):33392-9. PubMed ID: 12810712
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Redox process is crucial for inhibitory properties of aurintricarboxylic acid against activity of YopH: virulence factor of Yersinia pestis.
    Kuban-Jankowska A; Sahu KK; Niedzialkowski P; Gorska M; Tuszynski JA; Ossowski T; Wozniak M
    Oncotarget; 2015 Jul; 6(21):18364-73. PubMed ID: 26286963
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Yersinia pestis and approaches to targeting its outer protein H protein-tyrosine phosphatase (YopH).
    Bahta M; Burke TR
    Curr Med Chem; 2012; 19(33):5726-34. PubMed ID: 22934808
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tripeptide inhibitors of Yersinia protein-tyrosine phosphatase.
    Lee K; Gao Y; Yao ZJ; Phan J; Wu L; Liang J; Waugh DS; Zhang ZY; Burke TR
    Bioorg Med Chem Lett; 2003 Aug; 13(15):2577-81. PubMed ID: 12852970
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nuclear magnetic resonance and restrained molecular dynamics studies of the interaction of an epidermal growth factor-derived peptide with protein tyrosine phosphatase 1B.
    Glover NR; Tracey AS
    Biochemistry; 1999 Apr; 38(16):5256-71. PubMed ID: 10213634
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Parallel synthesis of a library of bidentate protein tyrosine phosphatase inhibitors based on the alpha-ketoacid motif.
    Chen YT; Seto CT
    Bioorg Med Chem; 2004 Jun; 12(12):3289-98. PubMed ID: 15158797
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Selective protein tyrosine phosphatase 1B inhibitors: targeting the second phosphotyrosine binding site with non-carboxylic acid-containing ligands.
    Liu G; Xin Z; Liang H; Abad-Zapatero C; Hajduk PJ; Janowick DA; Szczepankiewicz BG; Pei Z; Hutchins CW; Ballaron SJ; Stashko MA; Lubben TH; Berg CE; Rondinone CM; Trevillyan JM; Jirousek MR
    J Med Chem; 2003 Jul; 46(16):3437-40. PubMed ID: 12877578
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure of the Yersinia pestis type III secretion chaperone SycH in complex with a stable fragment of YscM2.
    Phan J; Tropea JE; Waugh DS
    Acta Crystallogr D Biol Crystallogr; 2004 Sep; 60(Pt 9):1591-9. PubMed ID: 15333930
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Derivatives of salicylic acid as inhibitors of YopH in Yersinia pestis.
    Huang Z; He Y; Zhang X; Gunawan A; Wu L; Zhang ZY; Wong CF
    Chem Biol Drug Des; 2010 Aug; 76(2):85-99. PubMed ID: 20560978
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Potent benzimidazole sulfonamide protein tyrosine phosphatase 1B inhibitors containing the heterocyclic (S)-isothiazolidinone phosphotyrosine mimetic.
    Combs AP; Zhu W; Crawley ML; Glass B; Polam P; Sparks RB; Modi D; Takvorian A; McLaughlin E; Yue EW; Wasserman Z; Bower M; Wei M; Rupar M; Ala PJ; Reid BM; Ellis D; Gonneville L; Emm T; Taylor N; Yeleswaram S; Li Y; Wynn R; Burn TC; Hollis G; Liu PC; Metcalf B
    J Med Chem; 2006 Jun; 49(13):3774-89. PubMed ID: 16789735
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Isothiazolidinone (IZD) as a phosphoryl mimetic in inhibitors of the Yersinia pestis protein tyrosine phosphatase YopH.
    Kim SE; Bahta M; Lountos GT; Ulrich RG; Burke TR; Waugh DS
    Acta Crystallogr D Biol Crystallogr; 2011 Jul; 67(Pt 7):639-45. PubMed ID: 21697602
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure-based optimization of protein tyrosine phosphatase 1B inhibitors: from the active site to the second phosphotyrosine binding site.
    Wilson DP; Wan ZK; Xu WX; Kirincich SJ; Follows BC; Joseph-McCarthy D; Foreman K; Moretto A; Wu J; Zhu M; Binnun E; Zhang YL; Tam M; Erbe DV; Tobin J; Xu X; Leung L; Shilling A; Tam SY; Mansour TS; Lee J
    J Med Chem; 2007 Sep; 50(19):4681-98. PubMed ID: 17705360
    [TBL] [Abstract][Full Text] [Related]  

  • 19. NMR-based design and evaluation of novel bidentate inhibitors of the protein tyrosine phosphatase YopH.
    Leone M; Barile E; Vazquez J; Mei A; Guiney D; Dahl R; Pellecchia M
    Chem Biol Drug Des; 2010 Jul; 76(1):10-6. PubMed ID: 20456369
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Solution structure and phosphopeptide binding to the N-terminal domain of Yersinia YopH: comparison with a crystal structure.
    Khandelwal P; Keliikuli K; Smith CL; Saper MA; Zuiderweg ER
    Biochemistry; 2002 Sep; 41(38):11425-37. PubMed ID: 12234185
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.