BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

351 related articles for article (PubMed ID: 14611643)

  • 21. Activation of PI3-kinase stimulates endocytosis of ROMK via Akt1/SGK1-dependent phosphorylation of WNK1.
    Cheng CJ; Huang CL
    J Am Soc Nephrol; 2011 Mar; 22(3):460-71. PubMed ID: 21355052
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.
    Navé BT; Ouwens M; Withers DJ; Alessi DR; Shepherd PR
    Biochem J; 1999 Dec; 344 Pt 2(Pt 2):427-31. PubMed ID: 10567225
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Role of the phosphatidylinositol 3-kinase/Akt and mTOR/P70S6-kinase pathways in the proliferation and apoptosis in multiple myeloma.
    Pene F; Claessens YE; Muller O; Viguié F; Mayeux P; Dreyfus F; Lacombe C; Bouscary D
    Oncogene; 2002 Sep; 21(43):6587-97. PubMed ID: 12242656
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Tumour necrosis factor-alpha activation of protein kinase B in WEHI-164 cells is accompanied by increased phosphorylation of Ser473, but not Thr308.
    O'toole A; Moule SK; Lockyer PJ; Halestrap AP
    Biochem J; 2001 Oct; 359(Pt 1):119-27. PubMed ID: 11563975
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B.
    Scheid MP; Marignani PA; Woodgett JR
    Mol Cell Biol; 2002 Sep; 22(17):6247-60. PubMed ID: 12167717
    [TBL] [Abstract][Full Text] [Related]  

  • 26. A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation.
    Frödin M; Antal TL; Dümmler BA; Jensen CJ; Deak M; Gammeltoft S; Biondi RM
    EMBO J; 2002 Oct; 21(20):5396-407. PubMed ID: 12374740
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Burn injury impairs insulin-stimulated Akt/PKB activation in skeletal muscle.
    Sugita H; Kaneki M; Sugita M; Yasukawa T; Yasuhara S; Martyn JA
    Am J Physiol Endocrinol Metab; 2005 Mar; 288(3):E585-91. PubMed ID: 15536206
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Ultraviolet-induced phosphorylation of p70(S6K) at Thr(389) and Thr(421)/Ser(424) involves hydrogen peroxide and mammalian target of rapamycin but not Akt and atypical protein kinase C.
    Huang C; Li J; Ke Q; Leonard SS; Jiang BH; Zhong XS; Costa M; Castranova V; Shi X
    Cancer Res; 2002 Oct; 62(20):5689-97. PubMed ID: 12384526
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Treatment with TNF-alpha and IFN-gamma alters the activation of SER/THR protein kinases and the metabolic response to IGF-I in mouse c2c12 myogenic cells.
    Grzelkowska-Kowalczyk K; Wieteska-Skrzeczyńska W
    Cell Mol Biol Lett; 2010; 15(1):13-31. PubMed ID: 19685010
    [TBL] [Abstract][Full Text] [Related]  

  • 30. 3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro.
    Alessi DR; Kozlowski MT; Weng QP; Morrice N; Avruch J
    Curr Biol; 1998 Jan; 8(2):69-81. PubMed ID: 9427642
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Growth factor-stimulated phosphorylation of Akt and p70(S6K) is differentially inhibited by LY294002 and Wortmannin.
    Adi S; Wu NY; Rosenthal SM
    Endocrinology; 2001 Jan; 142(1):498-501. PubMed ID: 11145615
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Serotonin-induced growth of pulmonary artery smooth muscle requires activation of phosphatidylinositol 3-kinase/serine-threonine protein kinase B/mammalian target of rapamycin/p70 ribosomal S6 kinase 1.
    Liu Y; Fanburg BL
    Am J Respir Cell Mol Biol; 2006 Feb; 34(2):182-91. PubMed ID: 16195541
    [TBL] [Abstract][Full Text] [Related]  

  • 33. The PIF-binding pocket in PDK1 is essential for activation of S6K and SGK, but not PKB.
    Biondi RM; Kieloch A; Currie RA; Deak M; Alessi DR
    EMBO J; 2001 Aug; 20(16):4380-90. PubMed ID: 11500365
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha.
    Alessi DR; James SR; Downes CP; Holmes AB; Gaffney PR; Reese CB; Cohen P
    Curr Biol; 1997 Apr; 7(4):261-9. PubMed ID: 9094314
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction.
    Burgering BM; Coffer PJ
    Nature; 1995 Aug; 376(6541):599-602. PubMed ID: 7637810
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Thyroid hormone induces rapid activation of Akt/protein kinase B-mammalian target of rapamycin-p70S6K cascade through phosphatidylinositol 3-kinase in human fibroblasts.
    Cao X; Kambe F; Moeller LC; Refetoff S; Seo H
    Mol Endocrinol; 2005 Jan; 19(1):102-12. PubMed ID: 15388791
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Differential regulation of the phosphoinositide 3-kinase and MAP kinase pathways by hepatocyte growth factor vs. insulin-like growth factor-I in myogenic cells.
    Halevy O; Cantley LC
    Exp Cell Res; 2004 Jul; 297(1):224-34. PubMed ID: 15194438
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Threonine phosphorylation of the beta 3 integrin cytoplasmic tail, at a site recognized by PDK1 and Akt/PKB in vitro, regulates Shc binding.
    Kirk RI; Sanderson MR; Lerea KM
    J Biol Chem; 2000 Oct; 275(40):30901-6. PubMed ID: 10896934
    [TBL] [Abstract][Full Text] [Related]  

  • 39. A new strategy for studying protein kinase B and its three isoforms. Role of protein kinase B in phosphorylating glycogen synthase kinase-3, tuberin, WNK1, and ATP citrate lyase.
    Sale EM; Hodgkinson CP; Jones NP; Sale GJ
    Biochemistry; 2006 Jan; 45(1):213-23. PubMed ID: 16388597
    [TBL] [Abstract][Full Text] [Related]  

  • 40. A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells.
    Sekulić A; Hudson CC; Homme JL; Yin P; Otterness DM; Karnitz LM; Abraham RT
    Cancer Res; 2000 Jul; 60(13):3504-13. PubMed ID: 10910062
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 18.