BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

128 related articles for article (PubMed ID: 14611855)

  • 1. Microcystin analogues comprised only of Adda and a single additional amino acid retain moderate activity as PP1/PP2A inhibitors.
    Gulledge BM; Aggen JB; Eng H; Sweimeh K; Chamberlin AR
    Bioorg Med Chem Lett; 2003 Sep; 13(17):2907-11. PubMed ID: 14611855
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Linearized and truncated microcystin analogues as inhibitors of protein phosphatases 1 and 2A.
    Gulledge BM; Aggen JB; Chamberlin AR
    Bioorg Med Chem Lett; 2003 Sep; 13(17):2903-6. PubMed ID: 14611854
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Use of a colorimetric protein phosphatase inhibition assay and enzyme linked immunosorbent assay for the study of microcystins and nodularins.
    An J; Carmichael WW
    Toxicon; 1994 Dec; 32(12):1495-507. PubMed ID: 7725318
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The microcystins and nodularins: cyclic polypeptide inhibitors of PP1 and PP2A.
    Gulledgea BM; Aggena JB; Huangb HB; Nairnc AC; Chamberlin AR
    Curr Med Chem; 2002 Nov; 9(22):1991-2003. PubMed ID: 12369867
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The design, synthesis, and biological evaluation of analogues of the serine-threonine protein phosphatase 1 and 2A selective inhibitor microcystin LA: rational modifications imparting PP1 selectivity.
    Aggen JB; Humphrey JM; Gauss CM; Huang HB; Nairn AC; Chamberlin AR
    Bioorg Med Chem; 1999 Mar; 7(3):543-64. PubMed ID: 10220039
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of several protein phosphatases by a non-covalently interacting microcystin and a novel cyanobacterial peptide, nostocyclin.
    Hastie CJ; Borthwick EB; Morrison LF; Codd GA; Cohen PT
    Biochim Biophys Acta; 2005 Nov; 1726(2):187-93. PubMed ID: 16046071
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular mechanisms underlying he interaction of motuporin and microcystins with type-1 and type-2A protein phosphatases.
    Craig M; Luu HA; McCready TL; Williams D; Andersen RJ; Holmes CF
    Biochem Cell Biol; 1996; 74(4):569-78. PubMed ID: 8960363
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Seco[D-Asp3]microcystin-RR and [D-Asp3,D-Glu(OMe)6]microcystin-RR, two new microcystins from a toxic water bloom of the cyanobacterium planktothrixrubescens.
    Grach-Pogrebinsky O; Sedmak B; Carmeli S
    J Nat Prod; 2004 Mar; 67(3):337-42. PubMed ID: 15043406
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Comparison of the solution structures of microcystin-LR and motuporin.
    Bagu JR; Sönnichsen FD; Williams D; Andersen RJ; Sykes BD; Holmes CF
    Nat Struct Biol; 1995 Feb; 2(2):114-6. PubMed ID: 7749913
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Bacterial degradation of microcystins and nodularin.
    Imanishi S; Kato H; Mizuno M; Tsuji K; Harada K
    Chem Res Toxicol; 2005 Mar; 18(3):591-8. PubMed ID: 15777098
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A molecular basis for different interactions of marine toxins with protein phosphatase-1. Molecular models for bound motuporin, microcystins, okadaic acid, and calyculin A.
    Bagu JR; Sykes BD; Craig MM; Holmes CF
    J Biol Chem; 1997 Feb; 272(8):5087-97. PubMed ID: 9030574
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cyanobacterial microcystin-LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants.
    MacKintosh C; Beattie KA; Klumpp S; Cohen P; Codd GA
    FEBS Lett; 1990 May; 264(2):187-92. PubMed ID: 2162782
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Microcystin-LR and okadaic acid-induced cellular effects: a dualistic response.
    Gehringer MM
    FEBS Lett; 2004 Jan; 557(1-3):1-8. PubMed ID: 14741332
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Solution structure of nodularin. An inhibitor of serine/threonine-specific protein phosphatases.
    Annila A; Lehtimäki J; Mattila K; Eriksson JE; Sivonen K; Rantala TT; Drakenberg T
    J Biol Chem; 1996 Jul; 271(28):16695-702. PubMed ID: 8663277
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The toxicology of microcystins.
    Dawson RM
    Toxicon; 1998 Jul; 36(7):953-62. PubMed ID: 9690788
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Crystal structures of protein phosphatase-1 bound to motuporin and dihydromicrocystin-LA: elucidation of the mechanism of enzyme inhibition by cyanobacterial toxins.
    Maynes JT; Luu HA; Cherney MM; Andersen RJ; Williams D; Holmes CF; James MN
    J Mol Biol; 2006 Feb; 356(1):111-20. PubMed ID: 16343532
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In vivo and in vitro binding of microcystin to protein phosphatases 1 and 2A.
    Runnegar M; Berndt N; Kong SM; Lee EY; Zhang L
    Biochem Biophys Res Commun; 1995 Nov; 216(1):162-9. PubMed ID: 7488083
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A fluorescent microplate assay for microcystin-LR.
    Fontal OI; Vieytes MR; Baptista de Sousa JM; Louzao MC; Botana LM
    Anal Biochem; 1999 May; 269(2):289-96. PubMed ID: 10222000
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure-function relationships of microcystins, liver tumor promoters, in interaction with protein phosphatase.
    Nishiwaki-Matsushima R; Nishiwaki S; Ohta T; Yoshizawa S; Suganuma M; Harada K; Watanabe MF; Fujiki H
    Jpn J Cancer Res; 1991 Sep; 82(9):993-6. PubMed ID: 1657848
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular mechanisms underlying inhibition of protein phosphatases by marine toxins.
    Dawson JF; Holmes CF
    Front Biosci; 1999 Oct; 4():D646-58. PubMed ID: 10502549
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.