319 related articles for article (PubMed ID: 14614141)
1. The base excision repair enzyme MED1 mediates DNA damage response to antitumor drugs and is associated with mismatch repair system integrity.
Cortellino S; Turner D; Masciullo V; Schepis F; Albino D; Daniel R; Skalka AM; Meropol NJ; Alberti C; Larue L; Bellacosa A
Proc Natl Acad Sci U S A; 2003 Dec; 100(25):15071-6. PubMed ID: 14614141
[TBL] [Abstract][Full Text] [Related]
2. Chromosomal instability, reproductive cell death and apoptosis induced by O6-methylguanine in Mex-, Mex+ and methylation-tolerant mismatch repair compromised cells: facts and models.
Kaina B; Ziouta A; Ochs K; Coquerelle T
Mutat Res; 1997 Nov; 381(2):227-41. PubMed ID: 9434879
[TBL] [Abstract][Full Text] [Related]
3. The DNA N-glycosylase MED1 exhibits preference for halogenated pyrimidines and is involved in the cytotoxicity of 5-iododeoxyuridine.
Turner DP; Cortellino S; Schupp JE; Caretti E; Loh T; Kinsella TJ; Bellacosa A
Cancer Res; 2006 Aug; 66(15):7686-93. PubMed ID: 16885370
[TBL] [Abstract][Full Text] [Related]
4. RAD51D protects against MLH1-dependent cytotoxic responses to O(6)-methylguanine.
Rajesh P; Rajesh C; Wyatt MD; Pittman DL
DNA Repair (Amst); 2010 Apr; 9(4):458-67. PubMed ID: 20133210
[TBL] [Abstract][Full Text] [Related]
5. Methylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2.
Adamson AW; Beardsley DI; Kim WJ; Gao Y; Baskaran R; Brown KD
Mol Biol Cell; 2005 Mar; 16(3):1513-26. PubMed ID: 15647386
[TBL] [Abstract][Full Text] [Related]
6. Exonuclease 1 (Exo1) is required for activating response to S(N)1 DNA methylating agents.
Izumchenko E; Saydi J; Brown KD
DNA Repair (Amst); 2012 Dec; 11(12):951-64. PubMed ID: 23062884
[TBL] [Abstract][Full Text] [Related]
7. Apoptosis triggered by DNA damage O6-methylguanine in human lymphocytes requires DNA replication and is mediated by p53 and Fas/CD95/Apo-1.
Roos W; Baumgartner M; Kaina B
Oncogene; 2004 Jan; 23(2):359-67. PubMed ID: 14724564
[TBL] [Abstract][Full Text] [Related]
8. Biphasic kinetics of the human DNA repair protein MED1 (MBD4), a mismatch-specific DNA N-glycosylase.
Petronzelli F; Riccio A; Markham GD; Seeholzer SH; Stoerker J; Genuardi M; Yeung AT; Matsumoto Y; Bellacosa A
J Biol Chem; 2000 Oct; 275(42):32422-9. PubMed ID: 10930409
[TBL] [Abstract][Full Text] [Related]
9. Investigation of the substrate spectrum of the human mismatch-specific DNA N-glycosylase MED1 (MBD4): fundamental role of the catalytic domain.
Petronzelli F; Riccio A; Markham GD; Seeholzer SH; Genuardi M; Karbowski M; Yeung AT; Matsumoto Y; Bellacosa A
J Cell Physiol; 2000 Dec; 185(3):473-80. PubMed ID: 11056019
[TBL] [Abstract][Full Text] [Related]
10. Homologous recombination rescues mismatch-repair-dependent cytotoxicity of S(N)1-type methylating agents in S. cerevisiae.
Cejka P; Mojas N; Gillet L; Schär P; Jiricny J
Curr Biol; 2005 Aug; 15(15):1395-400. PubMed ID: 16085492
[TBL] [Abstract][Full Text] [Related]
11. Role of MED1 (MBD4) Gene in DNA repair and human cancer.
Bellacosa A
J Cell Physiol; 2001 May; 187(2):137-44. PubMed ID: 11267993
[TBL] [Abstract][Full Text] [Related]
12. Processing of O6-methylguanine into DNA double-strand breaks requires two rounds of replication whereas apoptosis is also induced in subsequent cell cycles.
Quiros S; Roos WP; Kaina B
Cell Cycle; 2010 Jan; 9(1):168-78. PubMed ID: 20016283
[TBL] [Abstract][Full Text] [Related]
13. Mismatch repair and differential sensitivity of mouse and human cells to methylating agents.
Humbert O; Fiumicino S; Aquilina G; Branch P; Oda S; Zijno A; Karran P; Bignami M
Carcinogenesis; 1999 Feb; 20(2):205-14. PubMed ID: 10069455
[TBL] [Abstract][Full Text] [Related]
14. Modulation of the activity of methyl binding domain protein 4 (MBD4/MED1) while processing iododeoxyuridine generated DNA mispairs.
Aziz MA; Schupp JE; Kinsella TJ
Cancer Biol Ther; 2009 Jun; 8(12):1156-63. PubMed ID: 19395862
[TBL] [Abstract][Full Text] [Related]
15. Repair of O(6)-methylguanine is not affected by thymine base pairing and the presence of MMR proteins.
Lips J; Kaina B
Mutat Res; 2001 Nov; 487(1-2):59-66. PubMed ID: 11595409
[TBL] [Abstract][Full Text] [Related]
16. Triazene compounds: mechanism of action and related DNA repair systems.
Marchesi F; Turriziani M; Tortorelli G; Avvisati G; Torino F; De Vecchis L
Pharmacol Res; 2007 Oct; 56(4):275-87. PubMed ID: 17897837
[TBL] [Abstract][Full Text] [Related]
17. Evidence for a connection between the mismatch repair system and the G2 cell cycle checkpoint.
Hawn MT; Umar A; Carethers JM; Marra G; Kunkel TA; Boland CR; Koi M
Cancer Res; 1995 Sep; 55(17):3721-5. PubMed ID: 7641183
[TBL] [Abstract][Full Text] [Related]
18. Mismatch repair-dependent transcriptome changes in human cells treated with the methylating agent N-methyl-n'-nitro-N-nitrosoguanidine.
di Pietro M; Marra G; Cejka P; Stojic L; Menigatti M; Cattaruzza MS; Jiricny J
Cancer Res; 2003 Dec; 63(23):8158-66. PubMed ID: 14678970
[TBL] [Abstract][Full Text] [Related]
19. O6-Methylguanine DNA lesions induce an intra-S-phase arrest from which cells exit into apoptosis governed by early and late multi-pathway signaling network activation.
Noonan EM; Shah D; Yaffe MB; Lauffenburger DA; Samson LD
Integr Biol (Camb); 2012 Oct; 4(10):1237-55. PubMed ID: 22892544
[TBL] [Abstract][Full Text] [Related]
20. BER, MGMT, and MMR in defense against alkylation-induced genotoxicity and apoptosis.
Kaina B; Ochs K; Grösch S; Fritz G; Lips J; Tomicic M; Dunkern T; Christmann M
Prog Nucleic Acid Res Mol Biol; 2001; 68():41-54. PubMed ID: 11554312
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
