BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

716 related articles for article (PubMed ID: 14614574)

  • 1. Structure-activity study with bioreductive benzoquinone alkylating agents: effects on DT-diaphorase-mediated DNA crosslink and strand break formation in relation to mechanisms of cytotoxicity.
    Fourie J; Guziec F; Guziec L; Monterrosa C; Fiterman DJ; Begleiter A
    Cancer Chemother Pharmacol; 2004 Mar; 53(3):191-203. PubMed ID: 14614574
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The effect of functional groups on reduction and activation of quinone bioreductive agents by DT-diaphorase.
    Fourie J; Oleschuk CJ; Guziec F; Guziec L; Fiterman DJ; Monterrosa C; Begleiter A
    Cancer Chemother Pharmacol; 2002 Feb; 49(2):101-10. PubMed ID: 11862423
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Relationship between DT-diaphorase-mediated metabolism of a series of aziridinylbenzoquinones and DNA damage and cytotoxicity.
    Gibson NW; Hartley JA; Butler J; Siegel D; Ross D
    Mol Pharmacol; 1992 Sep; 42(3):531-6. PubMed ID: 1406604
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nicotinamide adenine dinucleotide (phosphate): quinone oxidoreductase (DT-diaphorase) as a target for bioreductive antitumor quinones: quinone cytotoxicity and selectivity in human lung and breast cancer cell lines.
    Beall HD; Murphy AM; Siegel D; Hargreaves RH; Butler J; Ross D
    Mol Pharmacol; 1995 Sep; 48(3):499-504. PubMed ID: 7565631
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Metabolism of bioreductive antitumor compounds by purified rat and human DT-diaphorases.
    Beall HD; Mulcahy RT; Siegel D; Traver RD; Gibson NW; Ross D
    Cancer Res; 1994 Jun; 54(12):3196-201. PubMed ID: 8205540
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activity of quinone alkylating agents in quinone-resistant cells.
    Begleiter A; Leith MK
    Cancer Res; 1990 May; 50(10):2872-6. PubMed ID: 1692249
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Quinone-induced DNA damage and its relationship to antitumor activity in L5178Y lymphoblasts.
    Begleiter A; Blair GW
    Cancer Res; 1984 Jan; 44(1):78-82. PubMed ID: 6537800
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterization of L5178Y murine lymphoblasts resistant to quinone antitumor agents.
    Begleiter A; Leith MK; McClarty G; Beenken S; Goldenberg GJ; Wright JA
    Cancer Res; 1988 Apr; 48(7):1727-35. PubMed ID: 3127038
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Role of NADPH cytochrome P450 reductase in activation of RH1.
    Begleiter A; Leith MK; Patel D; Hasinoff BB
    Cancer Chemother Pharmacol; 2007 Oct; 60(5):713-23. PubMed ID: 17256129
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-activity study of the interaction of bioreductive benzoquinone alkylating agents with DNA topoisomerase II.
    Hasinoff BB; Wu X; Begleiter A; Guziec LJ; Guziec F; Giorgianni A; Yang S; Jiang Y; Yalowich JC
    Cancer Chemother Pharmacol; 2006 Jan; 57(2):221-33. PubMed ID: 16010589
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mapping of DNA alkylation sites induced by aziridinylbenzoquinones in human cells by ligation-mediated polymerase chain reaction.
    Lee CS; Pfeifer GP; Gibson NW
    Cancer Res; 1994 Apr; 54(7):1622-6. PubMed ID: 8137269
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Metabolism of diaziquone by NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase): role in diaziquone-induced DNA damage and cytotoxicity in human colon carcinoma cells.
    Siegel D; Gibson NW; Preusch PC; Ross D
    Cancer Res; 1990 Nov; 50(22):7293-300. PubMed ID: 2121335
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Expression of DT-diaphorase and cytochrome P450 reductase correlates with mitomycin C activity in human bladder tumors.
    Gan Y; Mo Y; Kalns JE; Lu J; Danenberg K; Danenberg P; Wientjes MG; Au JL
    Clin Cancer Res; 2001 May; 7(5):1313-9. PubMed ID: 11350900
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Bioactivation of quinones by DT-diaphorase, molecular, biochemical, and chemical studies.
    Ross D; Beall H; Traver RD; Siegel D; Phillips RM; Gibson NW
    Oncol Res; 1994; 6(10-11):493-500. PubMed ID: 7620217
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cytotoxicity and DNA lesions produced by mitomycin C and porfiromycin in hypoxic and aerobic EMT6 and Chinese hamster ovary cells.
    Fracasso PM; Sartorelli AC
    Cancer Res; 1986 Aug; 46(8):3939-44. PubMed ID: 3089583
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [DT-diaphorase].
    Mikami K; Shirakusa T; Tsuruo T
    Gan To Kagaku Ryoho; 1997 Sep; 24(11):1606-10. PubMed ID: 9309161
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Elevated DT-diaphorase activity and messenger RNA content in human non-small cell lung carcinoma: relationship to the response of lung tumor xenografts to mitomycin Cł.
    Malkinson AM; Siegel D; Forrest GL; Gazdar AF; Oie HK; Chan DC; Bunn PA; Mabry M; Dykes DJ; Harrison SD
    Cancer Res; 1992 Sep; 52(17):4752-7. PubMed ID: 1324793
    [TBL] [Abstract][Full Text] [Related]  

  • 18. NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity.
    Traver RD; Horikoshi T; Danenberg KD; Stadlbauer TH; Danenberg PV; Ross D; Gibson NW
    Cancer Res; 1992 Feb; 52(4):797-802. PubMed ID: 1737339
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Induction of DT-diaphorase in cancer chemoprevention and chemotherapy.
    Begleiter A; Leith MK; Curphey TJ; Doherty GP
    Oncol Res; 1997; 9(6-7):371-82. PubMed ID: 9406243
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DT-diaphorase as a target enzyme for biochemical modulation of mitomycin C.
    Saeki S; Nishiyama M; Toge T
    Hiroshima J Med Sci; 1995 Sep; 44(3):55-63. PubMed ID: 8567314
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 36.