BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

145 related articles for article (PubMed ID: 14617668)

  • 21. Structure of and kinetic channelling in bifunctional dihydrofolate reductase-thymidylate synthase.
    Knighton DR; Kan CC; Howland E; Janson CA; Hostomska Z; Welsh KM; Matthews DA
    Nat Struct Biol; 1994 Mar; 1(3):186-94. PubMed ID: 7656037
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Construction of a fol mutant strain of Escherichia coli for use in dihydrofolate reductase mutagenesis experiments.
    Ahrweiler PM; Frieden C
    J Bacteriol; 1988 Jul; 170(7):3301-4. PubMed ID: 3290203
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Growth properties of a folA null mutant of Escherichia coli K12.
    Herrington MB; Chirwa NT
    Can J Microbiol; 1999 Mar; 45(3):191-200. PubMed ID: 10408091
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Cloning, expression, and characterization of Mycobacterium tuberculosis dihydrofolate reductase.
    White EL; Ross LJ; Cunningham A; Escuyer V
    FEMS Microbiol Lett; 2004 Mar; 232(1):101-5. PubMed ID: 15019741
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The roles of pteridine reductase 1 and dihydrofolate reductase-thymidylate synthase in pteridine metabolism in the protozoan parasite Leishmania major.
    Nare B; Hardy LW; Beverley SM
    J Biol Chem; 1997 May; 272(21):13883-91. PubMed ID: 9153248
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Engineering specificity for folate into dihydrofolate reductase from Escherichia coli.
    Posner BA; Li L; Bethell R; Tsuji T; Benkovic SJ
    Biochemistry; 1996 Feb; 35(5):1653-63. PubMed ID: 8634297
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Site-directed mutagenesis of mouse dihydrofolate reductase. Mutants with increased resistance to methotrexate and trimethoprim.
    Thillet J; Absil J; Stone SR; Pictet R
    J Biol Chem; 1988 Sep; 263(25):12500-8. PubMed ID: 3045118
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Does R67 dihydrofolate reductase possess a proton donor?
    Holland JC; Linn CE; DiGiammarino E; Nichols R; Howell EE
    Adv Exp Med Biol; 1993; 338():493-8. PubMed ID: 8304165
    [No Abstract]   [Full Text] [Related]  

  • 29. Reduction of Folate by Dihydrofolate Reductase from Thermotoga maritima.
    Loveridge EJ; Hroch L; Hughes RL; Williams T; Davies RL; Angelastro A; Luk LY; Maglia G; Allemann RK
    Biochemistry; 2017 Apr; 56(13):1879-1886. PubMed ID: 28319664
    [TBL] [Abstract][Full Text] [Related]  

  • 30. How adding a single methylene to dihydrofolate reductase can change its conformational dynamics.
    Penhallurick RW; Harold A; Durnal MD; Ichiye T
    J Chem Phys; 2021 Apr; 154(16):165103. PubMed ID: 33940851
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The dynamic energy landscape of dihydrofolate reductase catalysis.
    Boehr DD; McElheny D; Dyson HJ; Wright PE
    Science; 2006 Sep; 313(5793):1638-42. PubMed ID: 16973882
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Dihydrofolate reductase from a methotrexate-resistant strain of Escherichia coli: dihydrofolate monooxygenase activity.
    Poe M
    Biochem Biophys Res Commun; 1973 Oct; 54(3):1008-14. PubMed ID: 4584876
    [No Abstract]   [Full Text] [Related]  

  • 33. Trade-offs with stability modulate innate and mutationally acquired drug resistance in bacterial dihydrofolate reductase enzymes.
    Matange N; Bodkhe S; Patel M; Shah P
    Biochem J; 2018 Jun; 475(12):2107-2125. PubMed ID: 29871875
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Kinetic investigation of the functional role of phenylalanine-31 of recombinant human dihydrofolate reductase.
    Tsay JT; Appleman JR; Beard WA; Prendergast NJ; Delcamp TJ; Freisheim JH; Blakley RL
    Biochemistry; 1990 Jul; 29(27):6428-36. PubMed ID: 2207084
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Topological mutation of Escherichia coli dihydrofolate reductase.
    Iwakura M; Takenawa T; Nakamura T
    J Biochem; 1998 Oct; 124(4):769-77. PubMed ID: 9756622
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Functional expression of the dihydrofolate reductase domain of Leishmania major dihydrofolate reductase-thymidylate synthase bifunctional protein.
    Yu PL; Zhao J; Yu M; Reid R; Santi DV
    Protein Expr Purif; 1996 Aug; 8(1):23-7. PubMed ID: 8812831
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Secretion of genetically-engineered dihydrofolate reductase from Escherichia coli using an E. coli alpha-hemolysin membrane translocation system.
    Nakano H; Kawakami Y; Nishimura H
    Appl Microbiol Biotechnol; 1992 Sep; 37(6):765-71. PubMed ID: 1368920
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Identification and cloning of the Mycobacterium avium folA gene, required for dihydrofolate reductase activity.
    Zywno-van Ginkel S; Dooley TP; Suling WJ; Barrow WW
    FEMS Microbiol Lett; 1997 Nov; 156(1):69-78. PubMed ID: 9368362
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Isomorphous crystal structures of Escherichia coli dihydrofolate reductase complexed with folate, 5-deazafolate, and 5,10-dideazatetrahydrofolate: mechanistic implications.
    Reyes VM; Sawaya MR; Brown KA; Kraut J
    Biochemistry; 1995 Feb; 34(8):2710-23. PubMed ID: 7873554
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Testing the relationship between foldability and the early folding events of dihydrofolate reductase from Escherichia coli.
    Arai M; Maki K; Takahashi H; Iwakura M
    J Mol Biol; 2003 Apr; 328(1):273-88. PubMed ID: 12684013
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.