BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

293 related articles for article (PubMed ID: 14625550)

  • 1. Colonic polyposis caused by mTOR-mediated chromosomal instability in Apc+/Delta716 Cdx2+/- compound mutant mice.
    Aoki K; Tamai Y; Horiike S; Oshima M; Taketo MM
    Nat Genet; 2003 Dec; 35(4):323-30. PubMed ID: 14625550
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Suppression of colonic polyposis by homeoprotein CDX2 through its nontranscriptional function that stabilizes p27Kip1.
    Aoki K; Kakizaki F; Sakashita H; Manabe T; Aoki M; Taketo MM
    Cancer Res; 2011 Jan; 71(2):593-602. PubMed ID: 21224344
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CDX transcription factors positively regulate expression of solute carrier family 5, member 8 in the colonic epithelium.
    Kakizaki F; Aoki K; Miyoshi H; Carrasco N; Aoki M; Taketo MM
    Gastroenterology; 2010 Feb; 138(2):627-35. PubMed ID: 19900445
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Loss of single immunoglobulin interlukin-1 receptor-related molecule leads to enhanced colonic polyposis in Apc(min) mice.
    Xiao H; Yin W; Khan MA; Gulen MF; Zhou H; Sham HP; Jacobson K; Vallance BA; Li X
    Gastroenterology; 2010 Aug; 139(2):574-85. PubMed ID: 20416302
    [TBL] [Abstract][Full Text] [Related]  

  • 5. No effects of Smad2 (madh2) null mutation on malignant progression of intestinal polyps in Apc(delta716) knockout mice.
    Takaku K; Wrana JL; Robertson EJ; Taketo MM
    Cancer Res; 2002 Aug; 62(16):4558-61. PubMed ID: 12183405
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Chromosomal instability by beta-catenin/TCF transcription in APC or beta-catenin mutant cells.
    Aoki K; Aoki M; Sugai M; Harada N; Miyoshi H; Tsukamoto T; Mizoshita T; Tatematsu M; Seno H; Chiba T; Oshima M; Hsieh CL; Taketo MM
    Oncogene; 2007 May; 26(24):3511-20. PubMed ID: 17160019
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PLK1 has tumor-suppressive potential in APC-truncated colon cancer cells.
    Raab M; Sanhaji M; Matthess Y; Hörlin A; Lorenz I; Dötsch C; Habbe N; Waidmann O; Kurunci-Csacsko E; Firestein R; Becker S; Strebhardt K
    Nat Commun; 2018 Mar; 9(1):1106. PubMed ID: 29549256
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Morphological and molecular processes of polyp formation in Apc(delta716) knockout mice.
    Oshima H; Oshima M; Kobayashi M; Tsutsumi M; Taketo MM
    Cancer Res; 1997 May; 57(9):1644-9. PubMed ID: 9135000
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Colonic tumorigenesis in BubR1+/-ApcMin/+ compound mutant mice is linked to premature separation of sister chromatids and enhanced genomic instability.
    Rao CV; Yang YM; Swamy MV; Liu T; Fang Y; Mahmood R; Jhanwar-Uniyal M; Dai W
    Proc Natl Acad Sci U S A; 2005 Mar; 102(12):4365-70. PubMed ID: 15767571
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The threshold level of adenomatous polyposis coli protein for mouse intestinal tumorigenesis.
    Li Q; Ishikawa TO; Oshima M; Taketo MM
    Cancer Res; 2005 Oct; 65(19):8622-7. PubMed ID: 16204028
    [TBL] [Abstract][Full Text] [Related]  

  • 11. CDX2 has tumorigenic potential in the human colon cancer cell lines LOVO and SW48.
    Dang LH; Chen F; Ying C; Chun SY; Knock SA; Appelman HD; Dang DT
    Oncogene; 2006 Apr; 25(15):2264-72. PubMed ID: 16314840
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice.
    Hulit J; Wang C; Li Z; Albanese C; Rao M; Di Vizio D; Shah S; Byers SW; Mahmood R; Augenlicht LH; Russell R; Pestell RG
    Mol Cell Biol; 2004 Sep; 24(17):7598-611. PubMed ID: 15314168
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Key role of the Cdx2 homeobox gene in extracellular matrix-mediated intestinal cell differentiation.
    Lorentz O; Duluc I; Arcangelis AD; Simon-Assmann P; Kedinger M; Freund JN
    J Cell Biol; 1997 Dec; 139(6):1553-65. PubMed ID: 9396760
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of the mTORC1 pathway suppresses intestinal polyp formation and reduces mortality in ApcDelta716 mice.
    Fujishita T; Aoki K; Lane HA; Aoki M; Taketo MM
    Proc Natl Acad Sci U S A; 2008 Sep; 105(36):13544-9. PubMed ID: 18768809
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Reduced level of smoothened suppresses intestinal tumorigenesis by down-regulation of Wnt signaling.
    Arimura S; Matsunaga A; Kitamura T; Aoki K; Aoki M; Taketo MM
    Gastroenterology; 2009 Aug; 137(2):629-38. PubMed ID: 19427313
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Rapamycin inhibition of polyposis and progression to dysplasia in a mouse model.
    Hardiman KM; Liu J; Feng Y; Greenson JK; Fearon ER
    PLoS One; 2014; 9(4):e96023. PubMed ID: 24763434
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Loss of a single Hic1 allele accelerates polyp formation in Apc(Δ716) mice.
    Mohammad HP; Zhang W; Prevas HS; Leadem BR; Zhang M; Herman JG; Hooker CM; Watkins DN; Karim B; Huso DL; Baylin SB
    Oncogene; 2011 Jun; 30(23):2659-69. PubMed ID: 21297660
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cdx1 and Cdx2 function as tumor suppressors.
    Hryniuk A; Grainger S; Savory JG; Lohnes D
    J Biol Chem; 2014 Nov; 289(48):33343-54. PubMed ID: 25320087
    [TBL] [Abstract][Full Text] [Related]  

  • 19. mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways.
    Majumder PK; Febbo PG; Bikoff R; Berger R; Xue Q; McMahon LM; Manola J; Brugarolas J; McDonnell TJ; Golub TR; Loda M; Lane HA; Sellers WR
    Nat Med; 2004 Jun; 10(6):594-601. PubMed ID: 15156201
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Suppressing TGFβ signaling in regenerating epithelia in an inflammatory microenvironment is sufficient to cause invasive intestinal cancer.
    Oshima H; Nakayama M; Han TS; Naoi K; Ju X; Maeda Y; Robine S; Tsuchiya K; Sato T; Sato H; Taketo MM; Oshima M
    Cancer Res; 2015 Feb; 75(4):766-76. PubMed ID: 25687406
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.