BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

792 related articles for article (PubMed ID: 14626450)

  • 1. Selective inhibition of vascular endothelial growth factor receptor-2 (VEGFR-2) identifies a central role for VEGFR-2 in human aortic endothelial cell responses to VEGF.
    Endo A; Fukuhara S; Masuda M; Ohmori T; Mochizuki N
    J Recept Signal Transduct Res; 2003; 23(2-3):239-54. PubMed ID: 14626450
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Transactivation of vascular endothelial growth factor (VEGF) receptor Flk-1/KDR is involved in sphingosine 1-phosphate-stimulated phosphorylation of Akt and endothelial nitric-oxide synthase (eNOS).
    Tanimoto T; Jin ZG; Berk BC
    J Biol Chem; 2002 Nov; 277(45):42997-3001. PubMed ID: 12226078
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Vascular endothelial growth factor receptor-1 modulates vascular endothelial growth factor-mediated angiogenesis via nitric oxide.
    Bussolati B; Dunk C; Grohman M; Kontos CD; Mason J; Ahmed A
    Am J Pathol; 2001 Sep; 159(3):993-1008. PubMed ID: 11549592
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Phosphorylation of tyrosine 801 of vascular endothelial growth factor receptor-2 is necessary for Akt-dependent endothelial nitric-oxide synthase activation and nitric oxide release from endothelial cells.
    Blanes MG; Oubaha M; Rautureau Y; Gratton JP
    J Biol Chem; 2007 Apr; 282(14):10660-9. PubMed ID: 17303569
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ZM323881, a novel inhibitor of vascular endothelial growth factor-receptor-2 tyrosine kinase activity.
    Whittles CE; Pocock TM; Wedge SR; Kendrew J; Hennequin LF; Harper SJ; Bates DO
    Microcirculation; 2002 Dec; 9(6):513-22. PubMed ID: 12483548
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Vascular endothelial growth factor governs endothelial nitric-oxide synthase expression via a KDR/Flk-1 receptor and a protein kinase C signaling pathway.
    Shen BQ; Lee DY; Zioncheck TF
    J Biol Chem; 1999 Nov; 274(46):33057-63. PubMed ID: 10551875
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Vascular endothelial growth factor acts through novel, pregnancy-enhanced receptor signalling pathways to stimulate endothelial nitric oxide synthase activity in uterine artery endothelial cells.
    Grummer MA; Sullivan JA; Magness RR; Bird IM
    Biochem J; 2009 Jan; 417(2):501-11. PubMed ID: 18816248
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Src kinase becomes preferentially associated with the VEGFR, KDR/Flk-1, following VEGF stimulation of vascular endothelial cells.
    Chou MT; Wang J; Fujita DJ
    BMC Biochem; 2002 Dec; 3():32. PubMed ID: 12509223
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Flow shear stress stimulates Gab1 tyrosine phosphorylation to mediate protein kinase B and endothelial nitric-oxide synthase activation in endothelial cells.
    Jin ZG; Wong C; Wu J; Berk BC
    J Biol Chem; 2005 Apr; 280(13):12305-9. PubMed ID: 15665327
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Essential role of calcium in vascular endothelial growth factor A-induced signaling: mechanism of the antiangiogenic effect of carboxyamidotriazole.
    Faehling M; Kroll J; Föhr KJ; Fellbrich G; Mayr U; Trischler G; Waltenberger J
    FASEB J; 2002 Nov; 16(13):1805-7. PubMed ID: 12354692
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). A reassessment using novel receptor-specific vascular endothelial growth factor mutants.
    Gille H; Kowalski J; Li B; LeCouter J; Moffat B; Zioncheck TF; Pelletier N; Ferrara N
    J Biol Chem; 2001 Feb; 276(5):3222-30. PubMed ID: 11058584
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hepatocyte growth factor stimulates nitric oxide production through endothelial nitric oxide synthase activation by the phosphoinositide 3-kinase/Akt pathway and possibly by mitogen-activated protein kinase kinase in vascular endothelial cells.
    Uruno A; Sugawara A; Kanatsuka H; Arima S; Taniyama Y; Kudo M; Takeuchi K; Ito S
    Hypertens Res; 2004 Nov; 27(11):887-95. PubMed ID: 15824471
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The tyrosine kinase inhibitor cediranib blocks ligand-induced vascular endothelial growth factor receptor-3 activity and lymphangiogenesis.
    Heckman CA; Holopainen T; Wirzenius M; Keskitalo S; Jeltsch M; Ylä-Herttuala S; Wedge SR; Jürgensmeier JM; Alitalo K
    Cancer Res; 2008 Jun; 68(12):4754-62. PubMed ID: 18559522
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation.
    Gerber HP; McMurtrey A; Kowalski J; Yan M; Keyt BA; Dixit V; Ferrara N
    J Biol Chem; 1998 Nov; 273(46):30336-43. PubMed ID: 9804796
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Placenta growth factor stimulates MAP kinase and mitogenicity but not phospholipase C-gamma and migration of endothelial cells expressing Flt 1.
    Landgren E; Schiller P; Cao Y; Claesson-Welsh L
    Oncogene; 1998 Jan; 16(3):359-67. PubMed ID: 9467961
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Roles of two VEGF receptors, Flt-1 and KDR, in the signal transduction of VEGF effects in human vascular endothelial cells.
    Kanno S; Oda N; Abe M; Terai Y; Ito M; Shitara K; Tabayashi K; Shibuya M; Sato Y
    Oncogene; 2000 Apr; 19(17):2138-46. PubMed ID: 10815805
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Caveolin-1 expression is critical for vascular endothelial growth factor-induced ischemic hindlimb collateralization and nitric oxide-mediated angiogenesis.
    Sonveaux P; Martinive P; DeWever J; Batova Z; Daneau G; Pelat M; Ghisdal P; Grégoire V; Dessy C; Balligand JL; Feron O
    Circ Res; 2004 Jul; 95(2):154-61. PubMed ID: 15205364
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Chronic hypoxia attenuates VEGF signaling and angiogenic responses by downregulation of KDR in human endothelial cells.
    Olszewska-Pazdrak B; Hein TW; Olszewska P; Carney DH
    Am J Physiol Cell Physiol; 2009 May; 296(5):C1162-70. PubMed ID: 19244479
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Assessing the activity of cediranib, a VEGFR-2/3 tyrosine kinase inhibitor, against VEGFR-1 and members of the structurally related PDGFR family.
    Brave SR; Ratcliffe K; Wilson Z; James NH; Ashton S; Wainwright A; Kendrew J; Dudley P; Broadbent N; Sproat G; Taylor S; Barnes C; Silva JC; Farnsworth CL; Hennequin L; Ogilvie DJ; Jürgensmeier JM; Shibuya M; Wedge SR; Barry ST
    Mol Cancer Ther; 2011 May; 10(5):861-73. PubMed ID: 21441409
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ligand-independent activation of vascular endothelial growth factor receptor 2 by fluid shear stress regulates activation of endothelial nitric oxide synthase.
    Jin ZG; Ueba H; Tanimoto T; Lungu AO; Frame MD; Berk BC
    Circ Res; 2003 Aug; 93(4):354-63. PubMed ID: 12893742
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 40.