142 related articles for article (PubMed ID: 14627708)
1. Apomine, a novel hypocholesterolemic agent, accelerates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and stimulates low density lipoprotein receptor activity.
Roitelman J; Masson D; Avner R; Ammon-Zufferey C; Perez A; Guyon-Gellin Y; Bentzen CL; Niesor EJ
J Biol Chem; 2004 Feb; 279(8):6465-73. PubMed ID: 14627708
[TBL] [Abstract][Full Text] [Related]
2. The inhibition of degradation of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase by sterol regulatory element binding protein cleavage-activating protein requires four phenylalanine residues in span 6 of HMG-CoA reductase transmembrane domain.
Xu L; Simoni RD
Arch Biochem Biophys; 2003 Jun; 414(2):232-43. PubMed ID: 12781775
[TBL] [Abstract][Full Text] [Related]
3. Isolation of mutant cells lacking Insig-1 through selection with SR-12813, an agent that stimulates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
Sever N; Lee PC; Song BL; Rawson RB; Debose-Boyd RA
J Biol Chem; 2004 Oct; 279(41):43136-47. PubMed ID: 15247248
[TBL] [Abstract][Full Text] [Related]
4. The novel cholesterol-lowering drug SR-12813 inhibits cholesterol synthesis via an increased degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
Berkhout TA; Simon HM; Patel DD; Bentzen C; Niesor E; Jackson B; Suckling KE
J Biol Chem; 1996 Jun; 271(24):14376-82. PubMed ID: 8662919
[TBL] [Abstract][Full Text] [Related]
5. Lanosterol analogs: dual-action inhibitors of cholesterol biosynthesis.
Frye LL; Leonard DA
Crit Rev Biochem Mol Biol; 1999; 34(2):123-40. PubMed ID: 10333389
[TBL] [Abstract][Full Text] [Related]
6. Post-transcriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by mevalonate.
Straka MS; Panini SR
Arch Biochem Biophys; 1995 Feb; 317(1):235-43. PubMed ID: 7872789
[TBL] [Abstract][Full Text] [Related]
7. The mevalonate/isoprenoid pathway inhibitor apomine (SR-45023A) is antiproliferative and induces apoptosis similar to farnesol.
Flach J; Antoni I; Villemin P; Bentzen CL; Niesor EJ
Biochem Biophys Res Commun; 2000 Apr; 270(1):240-6. PubMed ID: 10733934
[TBL] [Abstract][Full Text] [Related]
8. The effects of lifibrol (K12.148) on the cholesterol metabolism of cultured cells: evidence for sterol independent stimulation of the LDL receptor pathway.
Scharnagl H; Schliack M; Löser R; Nauck M; Gierens H; Jeck N; Wieland H; Gross W; März W
Atherosclerosis; 2000 Nov; 153(1):69-80. PubMed ID: 11058701
[TBL] [Abstract][Full Text] [Related]
9. The ubiquitin-proteasome pathway mediates the regulated degradation of mammalian 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
Ravid T; Doolman R; Avner R; Harats D; Roitelman J
J Biol Chem; 2000 Nov; 275(46):35840-7. PubMed ID: 10964918
[TBL] [Abstract][Full Text] [Related]
10. Ubiquitin is conjugated by membrane ubiquitin ligase to three sites, including the N terminus, in transmembrane region of mammalian 3-hydroxy-3-methylglutaryl coenzyme A reductase: implications for sterol-regulated enzyme degradation.
Doolman R; Leichner GS; Avner R; Roitelman J
J Biol Chem; 2004 Sep; 279(37):38184-93. PubMed ID: 15247208
[TBL] [Abstract][Full Text] [Related]
11. Effects of a novel lanosterol 14 alpha-demethylase inhibitor on the regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in Hep G2 cells.
Mayer RJ; Adams JL; Bossard MJ; Berkhout TA
J Biol Chem; 1991 Oct; 266(30):20070-8. PubMed ID: 1657912
[TBL] [Abstract][Full Text] [Related]
12. Apomine enhances the antitumor effects of lovastatin on myeloma cells by down-regulating 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
Roelofs AJ; Edwards CM; Russell RG; Ebetino FH; Rogers MJ; Hulley PA
J Pharmacol Exp Ther; 2007 Jul; 322(1):228-35. PubMed ID: 17412884
[TBL] [Abstract][Full Text] [Related]
13. Synergistic inhibitory effect of apomine and lovastatin on osteosarcoma cell growth.
Moriceau G; Roelofs AJ; Brion R; Redini F; Ebetion FH; Rogers MJ; Heymann D
Cancer; 2012 Feb; 118(3):750-60. PubMed ID: 21751201
[TBL] [Abstract][Full Text] [Related]
14. 15-substituted lanosterols: post-transcriptional suppressors of 3-hydroxy-3-methylglutaryl coenzyme A reductase.
Anderson JA; Leonard DA; Cusack KP; Frye LL
Arch Biochem Biophys; 1995 Jan; 316(1):190-6. PubMed ID: 7840615
[TBL] [Abstract][Full Text] [Related]
15. Effects of 15-oxa-32-vinyl-lanost-8-ene-3 beta,32 diol on the expression of 3-hydroxy-3-methylglutaryl coenzyme A reductase and low density lipoprotein receptor in rat liver.
Ness GC; Lopez D; Chambers CM; Zhao Z; Beach DL; Ko SS; Trzaskos JM
Arch Biochem Biophys; 1998 Sep; 357(2):259-64. PubMed ID: 9735166
[TBL] [Abstract][Full Text] [Related]
16. Posttranscriptional regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in lens epithelial cells by mevalonate-derived nonsterols.
Cenedella RJ
Exp Eye Res; 1997 Jul; 65(1):63-72. PubMed ID: 9237866
[TBL] [Abstract][Full Text] [Related]
17. Sterols accelerate degradation of hamster 3-hydroxy-3-methylglutaryl coenzyme A reductase encoded by a constitutively expressed cDNA.
Chin DJ; Gil G; Faust JR; Goldstein JL; Brown MS; Luskey KL
Mol Cell Biol; 1985 Apr; 5(4):634-41. PubMed ID: 3838796
[TBL] [Abstract][Full Text] [Related]
18. Conjugated and non-conjugated octadecaenoic acids affect differently intestinal acyl coenzyme A: cholesterol acyltransferase activity.
Lam CK; Chen J; Cao Y; Yang L; Wong YM; Yeung SY; Yao X; Huang Y; Chen ZY
Atherosclerosis; 2008 May; 198(1):85-93. PubMed ID: 18078940
[TBL] [Abstract][Full Text] [Related]
19. Modulation of regulatory factors involved in cholesterol metabolism in response to feeding of pravastatin- or cholesterol-supplemented diet in chickens.
Matsuyama H; Sato K; Nakamura Y; Suzuki K; Akiba Y
Biochim Biophys Acta; 2005 May; 1734(2):136-42. PubMed ID: 15904870
[TBL] [Abstract][Full Text] [Related]
20. Sitosterol reduces messenger RNA and protein expression levels of Niemann-Pick C1-like 1 in FHs 74 Int cells.
Jesch ED; Seo JM; Carr TP; Lee JY
Nutr Res; 2009 Dec; 29(12):859-66. PubMed ID: 19963159
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
