BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

131 related articles for article (PubMed ID: 14627979)

  • 21. MLN120B, a novel IkappaB kinase beta inhibitor, blocks multiple myeloma cell growth in vitro and in vivo.
    Hideshima T; Neri P; Tassone P; Yasui H; Ishitsuka K; Raje N; Chauhan D; Podar K; Mitsiades C; Dang L; Munshi N; Richardson P; Schenkein D; Anderson KC
    Clin Cancer Res; 2006 Oct; 12(19):5887-94. PubMed ID: 17020997
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Accelerated proliferation of myeloma cells by interleukin-6 cooperating with fibroblast growth factor receptor 3-mediated signals.
    Ishikawa H; Tsuyama N; Liu S; Abroun S; Li FJ; Otsuyama K; Zheng X; Ma Z; Maki Y; Iqbal MS; Obata M; Kawano MM
    Oncogene; 2005 Sep; 24(41):6328-32. PubMed ID: 15940250
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Interleukin-6 inhibits cell proliferation in a rat model of hepatocellular carcinoma.
    Moran DM; Mayes N; Koniaris LG; Cahill PA; McKillop IH
    Liver Int; 2005 Apr; 25(2):445-57. PubMed ID: 15780071
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Novel inosine monophosphate dehydrogenase inhibitor VX-944 induces apoptosis in multiple myeloma cells primarily via caspase-independent AIF/Endo G pathway.
    Ishitsuka K; Hideshima T; Hamasaki M; Raje N; Kumar S; Podar K; Le Gouill S; Shiraishi N; Yasui H; Roccaro AM; Tai YZ; Chauhan D; Fram R; Tamura K; Jain J; Anderson KC
    Oncogene; 2005 Sep; 24(38):5888-96. PubMed ID: 15940263
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Synergistic induction of oxidative injury and apoptosis in human multiple myeloma cells by the proteasome inhibitor bortezomib and histone deacetylase inhibitors.
    Pei XY; Dai Y; Grant S
    Clin Cancer Res; 2004 Jun; 10(11):3839-52. PubMed ID: 15173093
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Interferon-gamma-induced sensitization of colon carcinomas to ZD9331 targets caspases, downstream of Fas, independent of mitochondrial signaling and the inhibitor of apoptosis survivin.
    Geller J; Petak I; Szucs KS; Nagy K; Tillman DM; Houghton JA
    Clin Cancer Res; 2003 Dec; 9(17):6504-15. PubMed ID: 14695155
    [TBL] [Abstract][Full Text] [Related]  

  • 27. No inhibition of IL-27 signaling by soluble gp130.
    Scheller J; Schuster B; Hölscher C; Yoshimoto T; Rose-John S
    Biochem Biophys Res Commun; 2005 Jan; 326(4):724-8. PubMed ID: 15607729
    [TBL] [Abstract][Full Text] [Related]  

  • 28. The effect of azacitidine on interleukin-6 signaling and nuclear factor-kappaB activation and its in vitro and in vivo activity against multiple myeloma.
    Khong T; Sharkey J; Spencer A
    Haematologica; 2008 Jun; 93(6):860-9. PubMed ID: 18443271
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Characteristics, pathogenesis, and novel treatments for multiple myeloma.
    San Miguel J
    J Natl Compr Canc Netw; 2004 Nov; 2 Suppl 4():S1-4. PubMed ID: 19791422
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Local blockade of IL-6R signaling induces lung CD4+ T cell apoptosis in a murine model of asthma via regulatory T cells.
    Finotto S; Eigenbrod T; Karwot R; Boross I; Doganci A; Ito H; Nishimoto N; Yoshizaki K; Kishimoto T; Rose-John S; Galle PR; Neurath MF
    Int Immunol; 2007 Jun; 19(6):685-93. PubMed ID: 17496315
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Capsaicin inhibits the IL-6/STAT3 pathway by depleting intracellular gp130 pools through endoplasmic reticulum stress.
    Lee HK; Seo IA; Shin YK; Park JW; Suh DJ; Park HT
    Biochem Biophys Res Commun; 2009 May; 382(2):445-50. PubMed ID: 19285962
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Caveolin-1 is required for vascular endothelial growth factor-triggered multiple myeloma cell migration and is targeted by bortezomib.
    Podar K; Shringarpure R; Tai YT; Simoncini M; Sattler M; Ishitsuka K; Richardson PG; Hideshima T; Chauhan D; Anderson KC
    Cancer Res; 2004 Oct; 64(20):7500-6. PubMed ID: 15492276
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Concomitant downregulation of proliferation/survival pathways dependent on FGF-R3, JAK2 and BCMA in human multiple myeloma cells by multi-kinase targeting.
    Cassinelli G; Ronchetti D; Laccabue D; Mattioli M; Cuccuru G; Favini E; Nicolini V; Greco A; Neri A; Zunino F; Lanzi C
    Biochem Pharmacol; 2009 Nov; 78(9):1139-47. PubMed ID: 19555670
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Caspase-mediated cleavage of the signal-transducing IL-6 receptor subunit gp130.
    Graf D; Haselow K; Münks I; Bode JG; Häussinger D
    Arch Biochem Biophys; 2008 Sep; 477(2):330-8. PubMed ID: 18593565
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Local activation of interleukin 6 signaling is associated with arteriovenous fistula stenosis in hemodialysis patients.
    Marrone D; Pertosa G; Simone S; Loverre A; Capobianco C; Cifarelli M; Memoli B; Schena FP; Grandaliano G
    Am J Kidney Dis; 2007 May; 49(5):664-73. PubMed ID: 17472849
    [TBL] [Abstract][Full Text] [Related]  

  • 36. An altered fibronectin matrix induces anoikis of human squamous cell carcinoma cells by suppressing integrin alpha v levels and phosphorylation of FAK and ERK.
    Kamarajan P; Kapila YL
    Apoptosis; 2007 Dec; 12(12):2221-31. PubMed ID: 17879163
    [TBL] [Abstract][Full Text] [Related]  

  • 37. The proteasome inhibitor PS-341 (bortezomib) up-regulates DR5 expression leading to induction of apoptosis and enhancement of TRAIL-induced apoptosis despite up-regulation of c-FLIP and survivin expression in human NSCLC cells.
    Liu X; Yue P; Chen S; Hu L; Lonial S; Khuri FR; Sun SY
    Cancer Res; 2007 May; 67(10):4981-8. PubMed ID: 17510429
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Degradation of PKB/Akt protein by inhibition of the VEGF receptor/mTOR pathway in endothelial cells.
    Riesterer O; Zingg D; Hummerjohann J; Bodis S; Pruschy M
    Oncogene; 2004 Jun; 23(26):4624-35. PubMed ID: 15064712
    [TBL] [Abstract][Full Text] [Related]  

  • 39. NF-kappa B as a therapeutic target in multiple myeloma.
    Hideshima T; Chauhan D; Richardson P; Mitsiades C; Mitsiades N; Hayashi T; Munshi N; Dang L; Castro A; Palombella V; Adams J; Anderson KC
    J Biol Chem; 2002 May; 277(19):16639-47. PubMed ID: 11872748
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Novel therapies targeting the myeloma cell and its bone marrow microenvironment.
    Hideshima T; Chauhan D; Podar K; Schlossman RL; Richardson P; Anderson KC
    Semin Oncol; 2001 Dec; 28(6):607-12. PubMed ID: 11740818
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.