These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

192 related articles for article (PubMed ID: 14628071)

  • 1. Inhibition of phosphatidylinositol 3-kinase dephosphorylates BAD and promotes apoptosis in myeloid leukemias.
    Zhao S; Konopleva M; Cabreira-Hansen M; Xie Z; Hu W; Milella M; Estrov Z; Mills GB; Andreeff M
    Leukemia; 2004 Feb; 18(2):267-75. PubMed ID: 14628071
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sensitisation of HL60 human leukaemic cells to cytotoxic drug-induced apoptosis by inhibition of PI3-kinase survival signals.
    O'Gorman DM; McKenna SL; McGahon AJ; Knox KA; Cotter TG
    Leukemia; 2000 Apr; 14(4):602-11. PubMed ID: 10764145
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells.
    Martelli AM; Tazzari PL; Tabellini G; Bortul R; Billi AM; Manzoli L; Ruggeri A; Conte R; Cocco L
    Leukemia; 2003 Sep; 17(9):1794-805. PubMed ID: 12970779
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The lethal effects of pharmacological cyclin-dependent kinase inhibitors in human leukemia cells proceed through a phosphatidylinositol 3-kinase/Akt-dependent process.
    Yu C; Rahmani M; Dai Y; Conrad D; Krystal G; Dent P; Grant S
    Cancer Res; 2003 Apr; 63(8):1822-33. PubMed ID: 12702569
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hemangiopoietin inhibits apoptosis of MO7e leukemia cells through phosphatidylinositol 3-kinase-AKT pathway.
    Zhan M; Han ZC
    Biochem Biophys Res Commun; 2004 Apr; 317(1):198-204. PubMed ID: 15047168
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of phosphatidylinositol 3'-kinase/AKT signaling promotes apoptosis of primary effusion lymphoma cells.
    Uddin S; Hussain AR; Al-Hussein KA; Manogaran PS; Wickrema A; Gutierrez MI; Bhatia KG
    Clin Cancer Res; 2005 Apr; 11(8):3102-8. PubMed ID: 15837766
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of the PI3K pathway sensitizes fludarabine-induced apoptosis in human leukemic cells through an inactivation of MAPK-dependent pathway.
    Yu C; Mao X; Li WX
    Biochem Biophys Res Commun; 2005 Jun; 331(2):391-7. PubMed ID: 15850772
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The PI3-kinase-Akt pathway promotes mesangial cell survival and inhibits apoptosis in vitro via NF-kappa B and Bad.
    Shimamura H; Terada Y; Okado T; Tanaka H; Inoshita S; Sasaki S
    J Am Soc Nephrol; 2003 Jun; 14(6):1427-34. PubMed ID: 12761242
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cytokine-induced protein kinase B activation and Bad phosphorylation do not correlate with cell survival of hemopoietic cells.
    Hinton HJ; Welham MJ
    J Immunol; 1999 Jun; 162(12):7002-9. PubMed ID: 10358141
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PI3K inhibition in neonatal rat brain slices during and after hypoxia reduces phospho-Akt and increases cytosolic cytochrome c and apoptosis.
    Hirai K; Hayashi T; Chan PH; Zeng J; Yang GY; Basus VJ; James TL; Litt L
    Brain Res Mol Brain Res; 2004 Apr; 124(1):51-61. PubMed ID: 15093685
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Long-term androgen-ablation causes increased resistance to PI3K/Akt pathway inhibition in prostate cancer cells.
    Pfeil K; Eder IE; Putz T; Ramoner R; Culig Z; Ueberall F; Bartsch G; Klocker H
    Prostate; 2004 Feb; 58(3):259-68. PubMed ID: 14743465
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PI3-kinase/Akt is constitutively active in primary acute myeloid leukaemia cells and regulates survival and chemoresistance via NF-kappaB, Mapkinase and p53 pathways.
    Grandage VL; Gale RE; Linch DC; Khwaja A
    Leukemia; 2005 Apr; 19(4):586-94. PubMed ID: 15703783
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Constitutively activated Akt-1 is vital for the survival of human monocyte-differentiated macrophages. Role of Mcl-1, independent of nuclear factor (NF)-kappaB, Bad, or caspase activation.
    Liu H; Perlman H; Pagliari LJ; Pope RM
    J Exp Med; 2001 Jul; 194(2):113-26. PubMed ID: 11457886
    [TBL] [Abstract][Full Text] [Related]  

  • 14. HGF protects corneal epithelial cells from apoptosis by the PI-3K/Akt-1/Bad- but not the ERK1/2-mediated signaling pathway.
    Kakazu A; Chandrasekher G; Bazan HE
    Invest Ophthalmol Vis Sci; 2004 Oct; 45(10):3485-92. PubMed ID: 15452053
    [TBL] [Abstract][Full Text] [Related]  

  • 15. C5b-9 terminal complement complex protects oligodendrocytes from death by regulating Bad through phosphatidylinositol 3-kinase/Akt pathway.
    Soane L; Cho HJ; Niculescu F; Rus H; Shin ML
    J Immunol; 2001 Aug; 167(4):2305-11. PubMed ID: 11490019
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inactivation of the antiapoptotic phosphatidylinositol 3-kinase-Akt pathway by the combined treatment of taxol and mitogen-activated protein kinase kinase inhibition.
    MacKeigan JP; Taxman DJ; Hunter D; Earp HS; Graves LM; Ting JP
    Clin Cancer Res; 2002 Jul; 8(7):2091-9. PubMed ID: 12114408
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Constitutive NF-kappaB DNA-binding activity in AML is frequently mediated by a Ras/PI3-K/PKB-dependent pathway.
    Birkenkamp KU; Geugien M; Schepers H; Westra J; Lemmink HH; Vellenga E
    Leukemia; 2004 Jan; 18(1):103-12. PubMed ID: 14574326
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Requirement for the PI3K/Akt pathway in MEK1-mediated growth and prevention of apoptosis: identification of an Achilles heel in leukemia.
    Blalock WL; Navolanic PM; Steelman LS; Shelton JG; Moye PW; Lee JT; Franklin RA; Mirza A; McMahon M; White MK; McCubrey JA
    Leukemia; 2003 Jun; 17(6):1058-67. PubMed ID: 12764369
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor perifosine in acute myelogenous leukemia cells.
    Papa V; Tazzari PL; Chiarini F; Cappellini A; Ricci F; Billi AM; Evangelisti C; Ottaviani E; Martinelli G; Testoni N; McCubrey JA; Martelli AM
    Leukemia; 2008 Jan; 22(1):147-60. PubMed ID: 17928881
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of phosphatidylinositol-3 kinase/Akt or mitogen-activated protein kinase signaling sensitizes endothelial cells to TNF-alpha cytotoxicity.
    Zhang L; Himi T; Morita I; Murota S
    Cell Death Differ; 2001 May; 8(5):528-36. PubMed ID: 11423913
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.