These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

164 related articles for article (PubMed ID: 14632453)

  • 1. Comparison of linear and nonlinear classification algorithms for the prediction of drug and chemical metabolism by human UDP-glucuronosyltransferase isoforms.
    Sorich MJ; Miners JO; McKinnon RA; Winkler DA; Burden FR; Smith PA
    J Chem Inf Comput Sci; 2003; 43(6):2019-24. PubMed ID: 14632453
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rapid prediction of chemical metabolism by human UDP-glucuronosyltransferase isoforms using quantum chemical descriptors derived with the electronegativity equalization method.
    Sorich MJ; McKinnon RA; Miners JO; Winkler DA; Smith PA
    J Med Chem; 2004 Oct; 47(21):5311-7. PubMed ID: 15456275
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Multiple pharmacophores for the investigation of human UDP-glucuronosyltransferase isoform substrate selectivity.
    Sorich MJ; Miners JO; McKinnon RA; Smith PA
    Mol Pharmacol; 2004 Feb; 65(2):301-8. PubMed ID: 14742671
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Comparison of support vector machine and artificial neural network systems for drug/nondrug classification.
    Byvatov E; Fechner U; Sadowski J; Schneider G
    J Chem Inf Comput Sci; 2003; 43(6):1882-9. PubMed ID: 14632437
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Prediction of P-glycoprotein substrates by a support vector machine approach.
    Xue Y; Yap CW; Sun LZ; Cao ZW; Wang JF; Chen YZ
    J Chem Inf Comput Sci; 2004; 44(4):1497-505. PubMed ID: 15272858
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Drug discovery using support vector machines. The case studies of drug-likeness, agrochemical-likeness, and enzyme inhibition predictions.
    Zernov VV; Balakin KV; Ivaschenko AA; Savchuk NP; Pletnev IV
    J Chem Inf Comput Sci; 2003; 43(6):2048-56. PubMed ID: 14632457
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Application of support vector machine (SVM) for prediction toxic activity of different data sets.
    Zhao CY; Zhang HX; Zhang XY; Liu MC; Hu ZD; Fan BT
    Toxicology; 2006 Jan; 217(2-3):105-19. PubMed ID: 16213080
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Modeling of human cytochrome p450-mediated drug metabolism using unsupervised machine learning approach.
    Korolev D; Balakin KV; Nikolsky Y; Kirillov E; Ivanenkov YA; Savchuk NP; Ivashchenko AA; Nikolskaya T
    J Med Chem; 2003 Aug; 46(17):3631-43. PubMed ID: 12904067
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Spline-fitting with a genetic algorithm: a method for developing classification structure-activity relationships.
    Sutherland JJ; O'Brien LA; Weaver DF
    J Chem Inf Comput Sci; 2003; 43(6):1906-15. PubMed ID: 14632439
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ADME evaluation in drug discovery. 8. The prediction of human intestinal absorption by a support vector machine.
    Hou T; Wang J; Li Y
    J Chem Inf Model; 2007; 47(6):2408-15. PubMed ID: 17929911
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The importance of local chemical structure for chemical metabolism by human uridine 5'-diphosphate-glucuronosyltransferase.
    Sorich MJ; McKinnon RA; Miners JO; Smith PA
    J Chem Inf Model; 2006; 46(6):2692-7. PubMed ID: 17125209
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Classification of estrogen receptor-beta ligands on the basis of their binding affinities using support vector machine and linear discriminant analysis.
    Luan F; Liu HT; Ma WP; Fan BT
    Eur J Med Chem; 2008 Jan; 43(1):43-52. PubMed ID: 17459530
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In silico human and rat Vss quantitative structure-activity relationship models.
    Gleeson MP; Waters NJ; Paine SW; Davis AM
    J Med Chem; 2006 Mar; 49(6):1953-63. PubMed ID: 16539383
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Benchmarking of linear and nonlinear approaches for quantitative structure-property relationship studies of metal complexation with ionophores.
    Tetko IV; Solov'ev VP; Antonov AV; Yao X; Doucet JP; Fan B; Hoonakker F; Fourches D; Jost P; Lachiche N; Varnek A
    J Chem Inf Model; 2006; 46(2):808-19. PubMed ID: 16563012
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In silico screening of estrogen-like chemicals based on different nonlinear classification models.
    Liu H; Papa E; Walker JD; Gramatica P
    J Mol Graph Model; 2007 Jul; 26(1):135-44. PubMed ID: 17293141
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Feature selection and linear/nonlinear regression methods for the accurate prediction of glycogen synthase kinase-3beta inhibitory activities.
    Goodarzi M; Freitas MP; Jensen R
    J Chem Inf Model; 2009 Apr; 49(4):824-32. PubMed ID: 19338295
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In silico log P prediction for a large data set with support vector machines, radial basis neural networks and multiple linear regression.
    Chen HF
    Chem Biol Drug Des; 2009 Aug; 74(2):142-7. PubMed ID: 19549084
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Towards integrated ADME prediction: past, present and future directions for modelling metabolism by UDP-glucuronosyltransferases.
    Smith PA; Sorich MJ; Low LS; McKinnon RA; Miners JO
    J Mol Graph Model; 2004 Jul; 22(6):507-17. PubMed ID: 15182810
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Bayesian framework for least-squares support vector machine classifiers, gaussian processes, and kernel Fisher discriminant analysis.
    Van Gestel T; Suykens JA; Lanckriet G; Lambrechts A; De Moor B; Vandewalle J
    Neural Comput; 2002 May; 14(5):1115-47. PubMed ID: 11972910
    [TBL] [Abstract][Full Text] [Related]  

  • 20. In vitro-in vivo correlation for drugs and other compounds eliminated by glucuronidation in humans: pitfalls and promises.
    Miners JO; Knights KM; Houston JB; Mackenzie PI
    Biochem Pharmacol; 2006 May; 71(11):1531-9. PubMed ID: 16455060
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.