BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

545 related articles for article (PubMed ID: 14633703)

  • 41. Effects of oncogenic ErbB2 on G1 cell cycle regulators in breast tumour cells.
    Neve RM; Sutterlüty H; Pullen N; Lane HA; Daly JM; Krek W; Hynes NE
    Oncogene; 2000 Mar; 19(13):1647-56. PubMed ID: 10763821
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Geldanamycin destabilizes HER2 tyrosine kinase and suppresses Wnt/beta-catenin signaling in HER2 overexpressing human breast cancer cells.
    Wang K; Ma Q; Ren Y; He J; Zhang Y; Zhang Y; Chen W
    Oncol Rep; 2007 Jan; 17(1):89-96. PubMed ID: 17143483
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Hsp90 inhibition transiently activates Src kinase and promotes Src-dependent Akt and Erk activation.
    Koga F; Xu W; Karpova TS; McNally JG; Baron R; Neckers L
    Proc Natl Acad Sci U S A; 2006 Jul; 103(30):11318-22. PubMed ID: 16844778
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Identification of an HSP90 modulated multi-step process for ERBB2 degradation in breast cancer cells.
    Castagnola P; Bellese G; Birocchi F; Gagliani MC; Tacchetti C; Cortese K
    Oncotarget; 2016 Dec; 7(51):85411-85429. PubMed ID: 27863425
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Herceptin-induced inhibition of phosphatidylinositol-3 kinase and Akt Is required for antibody-mediated effects on p27, cyclin D1, and antitumor action.
    Yakes FM; Chinratanalab W; Ritter CA; King W; Seelig S; Arteaga CL
    Cancer Res; 2002 Jul; 62(14):4132-41. PubMed ID: 12124352
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Activation of the phosphatidylinositol 3-kinase/Akt pathway prevents radiation-induced apoptosis in breast cancer cells.
    Söderlund K; Pérez-Tenorio G; Stål O
    Int J Oncol; 2005 Jan; 26(1):25-32. PubMed ID: 15586221
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Down-regulation of the erbB-2 receptor by trastuzumab (herceptin) enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in breast and ovarian cancer cell lines that overexpress erbB-2.
    Cuello M; Ettenberg SA; Clark AS; Keane MM; Posner RH; Nau MM; Dennis PA; Lipkowitz S
    Cancer Res; 2001 Jun; 61(12):4892-900. PubMed ID: 11406568
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Flotillin depletion affects ErbB protein levels in different human breast cancer cells.
    Asp N; Pust S; Sandvig K
    Biochim Biophys Acta; 2014 Sep; 1843(9):1987-96. PubMed ID: 24747692
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Anti-apoptotic effect of heat shock protein 90 on hypoxia-mediated cardiomyocyte damage is mediated via the phosphatidylinositol 3-kinase/AKT pathway.
    Wang W; Peng Y; Wang Y; Zhao X; Yuan Z
    Clin Exp Pharmacol Physiol; 2009 Sep; 36(9):899-903. PubMed ID: 19298537
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Enhanced sensitization to taxol-induced apoptosis by herceptin pretreatment in ErbB2-overexpressing breast cancer cells.
    Lee S; Yang W; Lan KH; Sellappan S; Klos K; Hortobagyi G; Hung MC; Yu D
    Cancer Res; 2002 Oct; 62(20):5703-10. PubMed ID: 12384528
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Stimulation of glycogen synthesis by heat shock in L6 skeletal-muscle cells: regulatory role of site-specific phosphorylation of glycogen-associated protein phosphatase 1.
    Moon B; Duddy N; Ragolia L; Begum N
    Biochem J; 2003 May; 371(Pt 3):857-66. PubMed ID: 12540292
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Pentagalloylglucose inhibits estrogen receptor alpha by lysosome-dependent depletion and modulates ErbB/PI3K/Akt pathway in human breast cancer MCF-7 cells.
    Hua KT; Way TD; Lin JK
    Mol Carcinog; 2006 Aug; 45(8):551-60. PubMed ID: 16637063
    [TBL] [Abstract][Full Text] [Related]  

  • 53. FLT3 expressing leukemias are selectively sensitive to inhibitors of the molecular chaperone heat shock protein 90 through destabilization of signal transduction-associated kinases.
    Yao Q; Nishiuchi R; Li Q; Kumar AR; Hudson WA; Kersey JH
    Clin Cancer Res; 2003 Oct; 9(12):4483-93. PubMed ID: 14555522
    [TBL] [Abstract][Full Text] [Related]  

  • 54. The benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin binds to HSP90 and shares important biologic activities with geldanamycin.
    Schulte TW; Neckers LM
    Cancer Chemother Pharmacol; 1998; 42(4):273-9. PubMed ID: 9744771
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Phosphorylation accelerates geldanamycin-induced Akt degradation.
    Su CH; Lan KH; Li CP; Chao Y; Lin HC; Lee SD; Lee WP
    Arch Biochem Biophys; 2013 Aug; 536(1):6-11. PubMed ID: 23668972
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Geldanamycin, an inhibitor of the chaperone activity of HSP90, induces MAPK-independent cell cycle arrest.
    Bedin M; Gaben AM; Saucier C; Mester J
    Int J Cancer; 2004 May; 109(5):643-52. PubMed ID: 14999769
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Herceptin-induced inhibition of ErbB2 signaling involves reduced phosphorylation of Akt but not endocytic down-regulation of ErbB2.
    Longva KE; Pedersen NM; Haslekås C; Stang E; Madshus IH
    Int J Cancer; 2005 Sep; 116(3):359-67. PubMed ID: 15800944
    [TBL] [Abstract][Full Text] [Related]  

  • 58. CAIR-1/BAG-3 abrogates heat shock protein-70 chaperone complex-mediated protein degradation: accumulation of poly-ubiquitinated Hsp90 client proteins.
    Doong H; Rizzo K; Fang S; Kulpa V; Weissman AM; Kohn EC
    J Biol Chem; 2003 Aug; 278(31):28490-500. PubMed ID: 12750378
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Chronic hypoxia increases endothelial nitric oxide synthase generation of nitric oxide by increasing heat shock protein 90 association and serine phosphorylation.
    Shi Y; Baker JE; Zhang C; Tweddell JS; Su J; Pritchard KA
    Circ Res; 2002 Aug; 91(4):300-6. PubMed ID: 12193462
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Cooperative inhibitory effect of ZD1839 (Iressa) in combination with trastuzumab (Herceptin) on human breast cancer cell growth.
    Normanno N; Campiglio M; De LA; Somenzi G; Maiello M; Ciardiello F; Gianni L; Salomon DS; Menard S
    Ann Oncol; 2002 Jan; 13(1):65-72. PubMed ID: 11863114
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 28.