BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

244 related articles for article (PubMed ID: 14636050)

  • 1. Identification of Tyr413 as an active site residue in the flavoprotein tryptophan 2-monooxygenase and analysis of its contribution to catalysis.
    Sobrado P; Fitzpatrick PF
    Biochemistry; 2003 Dec; 42(47):13833-8. PubMed ID: 14636050
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Analysis of the role of the active site residue Arg98 in the flavoprotein tryptophan 2-monooxygenase, a member of the L-amino oxidase family.
    Sobrado P; Fitzpatrick PF
    Biochemistry; 2003 Dec; 42(47):13826-32. PubMed ID: 14636049
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Analysis of the roles of amino acid residues in the flavoprotein tryptophan 2-monooxygenase modified by 2-oxo-3-pentynoate: characterization of His338, Cys339, and Cys511 mutant enzymes.
    Sobrado P; Fitzpatrick PF
    Arch Biochem Biophys; 2002 Jun; 402(1):24-30. PubMed ID: 12051679
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mechanistic studies of the flavoenzyme tryptophan 2-monooxygenase: deuterium and 15N kinetic isotope effects on alanine oxidation by an L-amino acid oxidase.
    Ralph EC; Anderson MA; Cleland WW; Fitzpatrick PF
    Biochemistry; 2006 Dec; 45(51):15844-52. PubMed ID: 17176107
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure of the flavoprotein tryptophan 2-monooxygenase, a key enzyme in the formation of galls in plants.
    Gaweska HM; Taylor AB; Hart PJ; Fitzpatrick PF
    Biochemistry; 2013 Apr; 52(15):2620-6. PubMed ID: 23521653
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Speeding up the product release: a second-sphere contribution from Tyr191 to the reactivity of L-lactate oxidase revealed in crystallographic and kinetic studies of site-directed variants.
    Stoisser T; Klimacek M; Wilson DK; Nidetzky B
    FEBS J; 2015 Nov; 282(21):4130-40. PubMed ID: 26260739
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Oxygen and hydrogen isotope effects in an active site tyrosine to phenylalanine mutant of peptidylglycine alpha-hydroxylating monooxygenase: mechanistic implications.
    Francisco WA; Blackburn NJ; Klinman JP
    Biochemistry; 2003 Feb; 42(7):1813-9. PubMed ID: 12590568
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanistic studies of mouse polyamine oxidase with N1,N12-bisethylspermine as a substrate.
    Royo M; Fitzpatrick PF
    Biochemistry; 2005 May; 44(18):7079-84. PubMed ID: 15865452
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Purification and characterization of the flavoprotein tryptophan 2-monooxygenase expressed at high levels in Escherichia coli.
    Emanuele JJ; Heasley CJ; Fitzpatrick PF
    Arch Biochem Biophys; 1995 Jan; 316(1):241-8. PubMed ID: 7840624
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Site-directed mutagenesis of glycine 99 to alanine in L-lactate monooxygenase from Mycobacterium smegmatis.
    Sun W; Williams CH; Massey V
    J Biol Chem; 1996 Jul; 271(29):17226-33. PubMed ID: 8663383
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of aspartate-133 and histidine-458 in the mechanism of tryptophan indole-lyase from Proteus vulgaris.
    Demidkina TV; Zakomirdina LN; Kulikova VV; Dementieva IS; Faleev NG; Ronda L; Mozzarelli A; Gollnick PD; Phillips RS
    Biochemistry; 2003 Sep; 42(38):11161-9. PubMed ID: 14503866
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Conserved tyrosine-369 in the active site of Escherichia coli copper amine oxidase is not essential.
    Murray JM; Kurtis CR; Tambyrajah W; Saysell CG; Wilmot CM; Parsons MR; Phillips SE; Knowles PF; McPherson MJ
    Biochemistry; 2001 Oct; 40(43):12808-18. PubMed ID: 11669617
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Selectivity of substrate binding and ionization of 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase.
    Luanloet T; Sucharitakul J; Chaiyen P
    FEBS J; 2015 Aug; 282(16):3107-25. PubMed ID: 25639849
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effects of noncovalent and covalent FAD binding on the redox and catalytic properties of p-cresol methylhydroxylase.
    Efimov I; Cronin CN; McIntire WS
    Biochemistry; 2001 Feb; 40(7):2155-66. PubMed ID: 11329284
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Steady-state kinetics and tryptophan fluorescence properties of halohydrin dehalogenase from Agrobacterium radiobacter. Roles of W139 and W249 in the active site and halide-induced conformational change.
    Tang L; van Merode AE; Lutje Spelberg JH; Fraaije MW; Janssen DB
    Biochemistry; 2003 Dec; 42(47):14057-65. PubMed ID: 14636074
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A catalytic triad is responsible for acid-base chemistry in the Ascaris suum NAD-malic enzyme.
    Karsten WE; Liu D; Rao GS; Harris BG; Cook PF
    Biochemistry; 2005 Mar; 44(9):3626-35. PubMed ID: 15736972
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Roles of active site aromatic residues in catalysis by ketosteroid isomerase from Pseudomonas putida biotype B.
    Kim DH; Nam GH; Jang DS; Choi G; Joo S; Kim JS; Oh BH; Choi KY
    Biochemistry; 1999 Oct; 38(42):13810-9. PubMed ID: 10529226
    [TBL] [Abstract][Full Text] [Related]  

  • 18. On the catalytic role of the conserved active site residue His466 of choline oxidase.
    Ghanem M; Gadda G
    Biochemistry; 2005 Jan; 44(3):893-904. PubMed ID: 15654745
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Alanine scanning mutagenesis of the testosterone binding site of rat 3 alpha-hydroxysteroid dehydrogenase demonstrates contact residues influence the rate-determining step.
    Heredia VV; Cooper WC; Kruger RG; Jin Y; Penning TM
    Biochemistry; 2004 May; 43(19):5832-41. PubMed ID: 15134457
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanistic insights into the dual activities of the single active site of l-lysine oxidase/monooxygenase from
    Trisrivirat D; Lawan N; Chenprakhon P; Matsui D; Asano Y; Chaiyen P
    J Biol Chem; 2020 Aug; 295(32):11246-11261. PubMed ID: 32527725
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.