230 related articles for article (PubMed ID: 14636322)
1. Dose-dependent induction of cytochrome P450 (CYP) 3A4 and activation of pregnane X receptor by topiramate.
Nallani SC; Glauser TA; Hariparsad N; Setchell K; Buckley DJ; Buckley AR; Desai PB
Epilepsia; 2003 Dec; 44(12):1521-8. PubMed ID: 14636322
[TBL] [Abstract][Full Text] [Related]
2. Differences in the induction of cytochrome P450 3A4 by taxane anticancer drugs, docetaxel and paclitaxel, assessed employing primary human hepatocytes.
Nallani SC; Goodwin B; Buckley AR; Buckley DJ; Desai PB
Cancer Chemother Pharmacol; 2004 Sep; 54(3):219-29. PubMed ID: 15175893
[TBL] [Abstract][Full Text] [Related]
3. Induction of CYP3A4 by efavirenz in primary human hepatocytes: comparison with rifampin and phenobarbital.
Hariparsad N; Nallani SC; Sane RS; Buckley DJ; Buckley AR; Desai PB
J Clin Pharmacol; 2004 Nov; 44(11):1273-81. PubMed ID: 15496645
[TBL] [Abstract][Full Text] [Related]
4. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
Cerveny L; Svecova L; Anzenbacherova E; Vrzal R; Staud F; Dvorak Z; Ulrichova J; Anzenbacher P; Pavek P
Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
[TBL] [Abstract][Full Text] [Related]
5. Induction of cytochrome P450 3A4 in primary human hepatocytes and activation of the human pregnane X receptor by tamoxifen and 4-hydroxytamoxifen.
Desai PB; Nallani SC; Sane RS; Moore LB; Goodwin BJ; Buckley DJ; Buckley AR
Drug Metab Dispos; 2002 May; 30(5):608-12. PubMed ID: 11950795
[TBL] [Abstract][Full Text] [Related]
6. Avasimibe induces CYP3A4 and multiple drug resistance protein 1 gene expression through activation of the pregnane X receptor.
Sahi J; Milad MA; Zheng X; Rose KA; Wang H; Stilgenbauer L; Gilbert D; Jolley S; Stern RH; LeCluyse EL
J Pharmacol Exp Ther; 2003 Sep; 306(3):1027-34. PubMed ID: 12766253
[TBL] [Abstract][Full Text] [Related]
7. Rifampicin induction of CYP3A4 requires pregnane X receptor cross talk with hepatocyte nuclear factor 4alpha and coactivators, and suppression of small heterodimer partner gene expression.
Li T; Chiang JY
Drug Metab Dispos; 2006 May; 34(5):756-64. PubMed ID: 16455805
[TBL] [Abstract][Full Text] [Related]
8. Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor.
Casabar RC; Das PC; Dekrey GK; Gardiner CS; Cao Y; Rose RL; Wallace AD
Toxicol Appl Pharmacol; 2010 Jun; 245(3):335-43. PubMed ID: 20361990
[TBL] [Abstract][Full Text] [Related]
9. The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module.
Goodwin B; Hodgson E; Liddle C
Mol Pharmacol; 1999 Dec; 56(6):1329-39. PubMed ID: 10570062
[TBL] [Abstract][Full Text] [Related]
10. Regulation of CYP2B6 in primary human hepatocytes by prototypical inducers.
Faucette SR; Wang H; Hamilton GA; Jolley SL; Gilbert D; Lindley C; Yan B; Negishi M; LeCluyse EL
Drug Metab Dispos; 2004 Mar; 32(3):348-58. PubMed ID: 14977870
[TBL] [Abstract][Full Text] [Related]
11. Calcium channel modulators of the dihydropyridine family are human pregnane X receptor activators and inducers of CYP3A, CYP2B, and CYP2C in human hepatocytes.
Drocourt L; Pascussi JM; Assenat E; Fabre JM; Maurel P; Vilarem MJ
Drug Metab Dispos; 2001 Oct; 29(10):1325-31. PubMed ID: 11560876
[TBL] [Abstract][Full Text] [Related]
12. CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes.
Luo G; Cunningham M; Kim S; Burn T; Lin J; Sinz M; Hamilton G; Rizzo C; Jolley S; Gilbert D; Downey A; Mudra D; Graham R; Carroll K; Xie J; Madan A; Parkinson A; Christ D; Selling B; LeCluyse E; Gan LS
Drug Metab Dispos; 2002 Jul; 30(7):795-804. PubMed ID: 12065438
[TBL] [Abstract][Full Text] [Related]
13. A cell-based reporter gene assay for determining induction of CYP3A4 in a high-volume system.
Raucy J; Warfe L; Yueh MF; Allen SW
J Pharmacol Exp Ther; 2002 Oct; 303(1):412-23. PubMed ID: 12235278
[TBL] [Abstract][Full Text] [Related]
14. Photochemotherapeutic agent 8-methoxypsoralen induces cytochrome P450 3A4 and carboxylesterase HCE2: evidence on an involvement of the pregnane X receptor.
Yang J; Yan B
Toxicol Sci; 2007 Jan; 95(1):13-22. PubMed ID: 17003103
[TBL] [Abstract][Full Text] [Related]
15. Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers.
Faucette SR; Zhang TC; Moore R; Sueyoshi T; Omiecinski CJ; LeCluyse EL; Negishi M; Wang H
J Pharmacol Exp Ther; 2007 Jan; 320(1):72-80. PubMed ID: 17041008
[TBL] [Abstract][Full Text] [Related]
16. Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes. Sequential role of glucocorticoid receptor and pregnane X receptor.
Pascussi JM; Drocourt L; Gerbal-Chaloin S; Fabre JM; Maurel P; Vilarem MJ
Eur J Biochem; 2001 Dec; 268(24):6346-58. PubMed ID: 11737189
[TBL] [Abstract][Full Text] [Related]
17. Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor.
Faucette SR; Sueyoshi T; Smith CM; Negishi M; Lecluyse EL; Wang H
J Pharmacol Exp Ther; 2006 Jun; 317(3):1200-9. PubMed ID: 16513849
[TBL] [Abstract][Full Text] [Related]
18. MDR1 genotype is associated with hepatic cytochrome P450 3A4 basal and induction phenotype.
Lamba J; Strom S; Venkataramanan R; Thummel KE; Lin YS; Liu W; Cheng C; Lamba V; Watkins PB; Schuetz E
Clin Pharmacol Ther; 2006 Apr; 79(4):325-38. PubMed ID: 16580901
[TBL] [Abstract][Full Text] [Related]
19. Regulation of the CYP3A4 gene by hydrocortisone and xenobiotics: role of the glucocorticoid and pregnane X receptors.
El-Sankary W; Plant NJ; Gibson GG; Moore DJ
Drug Metab Dispos; 2000 May; 28(5):493-6. PubMed ID: 10772626
[TBL] [Abstract][Full Text] [Related]
20. Impact of ritonavir, atazanavir and their combination on the CYP3A4 induction potential of efavirenz in primary human hepatocytes.
Mugundu GM; Hariparsad N; Desai PB
Drug Metab Lett; 2010 Jan; 4(1):45-50. PubMed ID: 20201776
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]