These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

206 related articles for article (PubMed ID: 14640697)

  • 1. Broad substrate specificity of human cytochrome P450 46A1 which initiates cholesterol degradation in the brain.
    Mast N; Norcross R; Andersson U; Shou M; Nakayama K; Bjorkhem I; Pikuleva IA
    Biochemistry; 2003 Dec; 42(48):14284-92. PubMed ID: 14640697
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activities of recombinant human cytochrome P450c27 (CYP27) which produce intermediates of alternative bile acid biosynthetic pathways.
    Pikuleva IA; Babiker A; Waterman MR; Björkhem I
    J Biol Chem; 1998 Jul; 273(29):18153-60. PubMed ID: 9660774
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Oxidation of 7-dehydrocholesterol and desmosterol by human cytochrome P450 46A1.
    Goyal S; Xiao Y; Porter NA; Xu L; Guengerich FP
    J Lipid Res; 2014 Sep; 55(9):1933-43. PubMed ID: 25017465
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 7 alpha hydroxylation of 25-hydroxycholesterol in liver microsomes. Evidence that the enzyme involved is different from cholesterol 7 alpha-hydroxylase.
    Toll A; Wikvall K; Sudjana-Sugiaman E; Kondo KH; Björkhem I
    Eur J Biochem; 1994 Sep; 224(2):309-16. PubMed ID: 7925343
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Expression of human cytochrome P450 46A1 in Escherichia coli: effects of N- and C-terminal modifications.
    Mast N; Andersson U; Nakayama K; Bjorkhem I; Pikuleva IA
    Arch Biochem Biophys; 2004 Aug; 428(1):99-108. PubMed ID: 15234274
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Human steroid and oxysterol 7α-hydroxylase CYP7B1: substrate specificity, azole binding and misfolding of clinically relevant mutants.
    Yantsevich AV; Dichenko YV; Mackenzie F; Mukha DV; Baranovsky AV; Gilep AA; Usanov SA; Strushkevich NV
    FEBS J; 2014 Mar; 281(6):1700-13. PubMed ID: 24491228
    [TBL] [Abstract][Full Text] [Related]  

  • 7. cyp7b1 catalyses the 7alpha-hydroxylation of dehydroepiandrosterone and 25-hydroxycholesterol in rat prostate.
    Martin C; Bean R; Rose K; Habib F; Seckl J
    Biochem J; 2001 Apr; 355(Pt 2):509-15. PubMed ID: 11284740
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Hydrophobic side chain requirements for lauric acid and progesterone hydroxylation at amino acid 113 in cytochrome P450 2C2, a potential determinant of substrate specificity.
    Straub P; Johnson EF; Kemper B
    Arch Biochem Biophys; 1993 Nov; 306(2):521-7. PubMed ID: 8215458
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cholesterol-metabolizing cytochromes P450.
    Pikuleva IA
    Drug Metab Dispos; 2006 Apr; 34(4):513-20. PubMed ID: 16434543
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Crystal structures of substrate-bound and substrate-free cytochrome P450 46A1, the principal cholesterol hydroxylase in the brain.
    Mast N; White MA; Bjorkhem I; Johnson EF; Stout CD; Pikuleva IA
    Proc Natl Acad Sci U S A; 2008 Jul; 105(28):9546-51. PubMed ID: 18621681
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Combined use of mass spectrometry and heterologous expression for identification of membrane-interacting peptides in cytochrome P450 46A1 and NADPH-cytochrome P450 oxidoreductase.
    Mast N; Liao WL; Pikuleva IA; Turko IV
    Arch Biochem Biophys; 2009 Mar; 483(1):81-9. PubMed ID: 19161969
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 24-hydroxycholesterol is a substrate for hepatic cholesterol 7alpha-hydroxylase (CYP7A).
    Norlin M; Toll A; Björkhem I; Wikvall K
    J Lipid Res; 2000 Oct; 41(10):1629-39. PubMed ID: 11013305
    [TBL] [Abstract][Full Text] [Related]  

  • 13. CYP46A1-dependent and independent effects of efavirenz treatment.
    Mast N; El-Darzi N; Petrov AM; Li Y; Pikuleva IA
    Brain Commun; 2020; 2(2):fcaa180. PubMed ID: 33305262
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The antifungal drug voriconazole is an efficient inhibitor of brain cholesterol 24S-hydroxylase in vitro and in vivo.
    Shafaati M; Mast N; Beck O; Nayef R; Heo GY; Björkhem-Bergman L; Lütjohann D; Björkhem I; Pikuleva IA
    J Lipid Res; 2010 Feb; 51(2):318-23. PubMed ID: 19474457
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Oxysterol 7 alpha-hydroxylase activity by cholesterol 7 alpha-hydroxylase (CYP7A).
    Norlin M; Andersson U; Björkhem I; Wikvall K
    J Biol Chem; 2000 Nov; 275(44):34046-53. PubMed ID: 10882719
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Putative helix F contributes to regioselectivity of hydroxylation in mitochondrial cytochrome P450 27A1.
    Pikuleva IA; Puchkaev A; Björkhem I
    Biochemistry; 2001 Jun; 40(25):7621-9. PubMed ID: 11412116
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pharmacologic stimulation of cytochrome P450 46A1 and cerebral cholesterol turnover in mice.
    Mast N; Li Y; Linger M; Clark M; Wiseman J; Pikuleva IA
    J Biol Chem; 2014 Feb; 289(6):3529-38. PubMed ID: 24352658
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 7 alpha-hydroxylation of 27-hydroxycholesterol: biologic role in the regulation of cholesterol synthesis.
    Martin KO; Reiss AB; Lathe R; Javitt NB
    J Lipid Res; 1997 May; 38(5):1053-8. PubMed ID: 9186922
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 24-, 25- and 27-hydroxylation of cholesterol by a purified preparation of 27-hydroxylase from pig liver.
    Lund E; Björkhem I; Furster C; Wikvall K
    Biochim Biophys Acta; 1993 Feb; 1166(2-3):177-82. PubMed ID: 8443234
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure and functions of human oxysterol 7alpha-hydroxylase cDNAs and gene CYP7B1.
    Wu Z; Martin KO; Javitt NB; Chiang JY
    J Lipid Res; 1999 Dec; 40(12):2195-203. PubMed ID: 10588945
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.