BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1058 related articles for article (PubMed ID: 14645546)

  • 1. Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation.
    Hu CJ; Wang LY; Chodosh LA; Keith B; Simon MC
    Mol Cell Biol; 2003 Dec; 23(24):9361-74. PubMed ID: 14645546
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differential regulation of the transcriptional activities of hypoxia-inducible factor 1 alpha (HIF-1alpha) and HIF-2alpha in stem cells.
    Hu CJ; Iyer S; Sataur A; Covello KL; Chodosh LA; Simon MC
    Mol Cell Biol; 2006 May; 26(9):3514-26. PubMed ID: 16611993
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Prolonged hypoxia differentially regulates hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression in lung epithelial cells: implication of natural antisense HIF-1alpha.
    Uchida T; Rossignol F; Matthay MA; Mounier R; Couette S; Clottes E; Clerici C
    J Biol Chem; 2004 Apr; 279(15):14871-8. PubMed ID: 14744852
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differentiating the functional role of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha (EPAS-1) by the use of RNA interference: erythropoietin is a HIF-2alpha target gene in Hep3B and Kelly cells.
    Warnecke C; Zaborowska Z; Kurreck J; Erdmann VA; Frei U; Wiesener M; Eckardt KU
    FASEB J; 2004 Sep; 18(12):1462-4. PubMed ID: 15240563
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1alpha (HIF-1alpha): role of cytoplasmic trapping of HIF-2alpha.
    Park SK; Dadak AM; Haase VH; Fontana L; Giaccia AJ; Johnson RS
    Mol Cell Biol; 2003 Jul; 23(14):4959-71. PubMed ID: 12832481
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1alpha.
    Wiesener MS; Turley H; Allen WE; Willam C; Eckardt KU; Talks KL; Wood SM; Gatter KC; Harris AL; Pugh CW; Ratcliffe PJ; Maxwell PH
    Blood; 1998 Oct; 92(7):2260-8. PubMed ID: 9746763
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regulation of HIF prolyl hydroxylases by hypoxia-inducible factors.
    Aprelikova O; Chandramouli GV; Wood M; Vasselli JR; Riss J; Maranchie JK; Linehan WM; Barrett JC
    J Cell Biochem; 2004 Jun; 92(3):491-501. PubMed ID: 15156561
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differential gene up-regulation by hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha in HEK293T cells.
    Wang V; Davis DA; Haque M; Huang LE; Yarchoan R
    Cancer Res; 2005 Apr; 65(8):3299-306. PubMed ID: 15833863
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
    Krieg M; Haas R; Brauch H; Acker T; Flamme I; Plate KH
    Oncogene; 2000 Nov; 19(48):5435-43. PubMed ID: 11114720
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: the role of HIF-1alpha, HIF-2alpha, and other pathways.
    Elvidge GP; Glenny L; Appelhoff RJ; Ratcliffe PJ; Ragoussis J; Gleadle JM
    J Biol Chem; 2006 Jun; 281(22):15215-26. PubMed ID: 16565084
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Subcellular localization and regulation of hypoxia-inducible factor-2alpha in vascular endothelial cells.
    Takahashi R; Kobayashi C; Kondo Y; Nakatani Y; Kudo I; Kunimoto M; Imura N; Hara S
    Biochem Biophys Res Commun; 2004 Apr; 317(1):84-91. PubMed ID: 15047151
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway.
    Carroll VA; Ashcroft M
    Cancer Res; 2006 Jun; 66(12):6264-70. PubMed ID: 16778202
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Genome-wide association of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha DNA binding with expression profiling of hypoxia-inducible transcripts.
    Mole DR; Blancher C; Copley RR; Pollard PJ; Gleadle JM; Ragoussis J; Ratcliffe PJ
    J Biol Chem; 2009 Jun; 284(25):16767-16775. PubMed ID: 19386601
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The specific contribution of hypoxia-inducible factor-2alpha to hypoxic gene expression in vitro is limited and modulated by cell type-specific and exogenous factors.
    Warnecke C; Weidemann A; Volke M; Schietke R; Wu X; Knaup KX; Hackenbeck T; Bernhardt W; Willam C; Eckardt KU; Wiesener MS
    Exp Cell Res; 2008 Jun; 314(10):2016-27. PubMed ID: 18420194
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages.
    Talks KL; Turley H; Gatter KC; Maxwell PH; Pugh CW; Ratcliffe PJ; Harris AL
    Am J Pathol; 2000 Aug; 157(2):411-21. PubMed ID: 10934146
    [TBL] [Abstract][Full Text] [Related]  

  • 16. HIF-1alpha and -2alpha genes in a hypoxia-sensitive teleost species Megalobrama amblycephala: cDNA cloning, expression and different responses to hypoxia.
    Shen RJ; Jiang XY; Pu JW; Zou SM
    Comp Biochem Physiol B Biochem Mol Biol; 2010 Nov; 157(3):273-80. PubMed ID: 20615476
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The N-terminal transactivation domain confers target gene specificity of hypoxia-inducible factors HIF-1alpha and HIF-2alpha.
    Hu CJ; Sataur A; Wang L; Chen H; Simon MC
    Mol Biol Cell; 2007 Nov; 18(11):4528-42. PubMed ID: 17804822
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of ETS transcription factors in the hypoxia-inducible factor-2 target gene selection.
    Aprelikova O; Wood M; Tackett S; Chandramouli GV; Barrett JC
    Cancer Res; 2006 Jun; 66(11):5641-7. PubMed ID: 16740701
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cooperative interaction of hypoxia-inducible factor-2alpha (HIF-2alpha ) and Ets-1 in the transcriptional activation of vascular endothelial growth factor receptor-2 (Flk-1).
    Elvert G; Kappel A; Heidenreich R; Englmeier U; Lanz S; Acker T; Rauter M; Plate K; Sieweke M; Breier G; Flamme I
    J Biol Chem; 2003 Feb; 278(9):7520-30. PubMed ID: 12464608
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nuclear localization of hypoxia-inducible factor-2alpha in bovine arterial endothelial cells.
    Hara S; Kobayashi C; Imura N
    Mol Cell Biol Res Commun; 1999 Aug; 2(2):119-23. PubMed ID: 10542135
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 53.