BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

317 related articles for article (PubMed ID: 14648018)

  • 21. Hepatocellular carcinoma cell lines from diethylnitrosamine phenobarbital-treated rats. Characterization and sensitivity to endothall, a protein serine/threonine phosphatase-2A inhibitor.
    Thièry JP; Blazsek I; Legras S; Marion S; Reynes M; Anjo A; Adam R; Misset JL
    Hepatology; 1999 May; 29(5):1406-17. PubMed ID: 10216123
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Impact of polyglutamation on sensitivity to raltitrexed and methotrexate in relation to drug-induced inhibition of de novo thymidylate and purine biosynthesis in CCRF-CEM cell lines.
    Barnes MJ; Estlin EJ; Taylor GA; Aherne GW; Hardcastle A; McGuire JJ; Calvete JA; Lunec J; Pearson AD; Newell DR
    Clin Cancer Res; 1999 Sep; 5(9):2548-58. PubMed ID: 10499632
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Molecular mechanism underlying the synergistic interaction between trifluorothymidine and the epidermal growth factor receptor inhibitor erlotinib in human colorectal cancer cell lines.
    Bijnsdorp IV; Kruyt FA; Fukushima M; Smid K; Gokoel S; Peters GJ
    Cancer Sci; 2010 Feb; 101(2):440-7. PubMed ID: 19886911
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Synergistic antitumour effect of raltitrexed and 5-fluorouracil plus folinic acid combination in human cancer cells.
    Avallone A; Di Gennaro E; Bruzzese F; Laus G; Delrio P; Caraglia M; Pepe S; Comella P; Budillon A
    Anticancer Drugs; 2007 Aug; 18(7):781-91. PubMed ID: 17581300
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Biological activity of the multitargeted antifolate, MTA (LY231514), in human cell lines with different resistance mechanisms to antifolate drugs.
    Schultz RM; Chen VJ; Bewley JR; Roberts EF; Shih C; Dempsey JA
    Semin Oncol; 1999 Apr; 26(2 Suppl 6):68-73. PubMed ID: 10598558
    [TBL] [Abstract][Full Text] [Related]  

  • 26. P21Cip1 is a critical mediator of the cytotoxic action of thymidylate synthase inhibitors in colorectal carcinoma cells.
    Geller JI; Szekely-Szucs K; Petak I; Doyle B; Houghton JA
    Cancer Res; 2004 Sep; 64(17):6296-303. PubMed ID: 15342418
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Determinants of activity of the antifolate thymidylate synthase inhibitors Tomudex (ZD1694) and GW1843U89 against mono- and multilayered colon cancer cell lines under folate-restricted conditions.
    Peters GJ; Smitskamp-Wilms E; Smid K; Pinedo HM; Jansen G
    Cancer Res; 1999 Nov; 59(21):5529-35. PubMed ID: 10554030
    [TBL] [Abstract][Full Text] [Related]  

  • 28. The inhibition of protein phosphatases 1 and 2A: a new target for rational anti-cancer drug design?
    McCluskey A; Ackland SP; Gardiner E; Walkom CC; Sakoff JA
    Anticancer Drug Des; 2001 Dec; 16(6):291-303. PubMed ID: 12375882
    [TBL] [Abstract][Full Text] [Related]  

  • 29. [Effects of RNA interference and nolatrexed on thymidylate synthase expression and cell proliferation of human colorectal carcinoma LOVO cells].
    Tian SB; Jing CQ; Li LP
    Zhonghua Wei Chang Wai Ke Za Zhi; 2012 Nov; 15(11):1187-91. PubMed ID: 23172536
    [TBL] [Abstract][Full Text] [Related]  

  • 30. An evaluation of thymidine phosphorylase as a means of preventing thymidine rescue from the thymidylate synthase inhibitor raltitrexed.
    Graham-Cole CL; Thomas HD; Taylor GA; Newell DR; Melton RG; Hesp R; Boddy AV
    Cancer Chemother Pharmacol; 2007 Feb; 59(2):197-206. PubMed ID: 16721548
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The histone deacetylase inhibitor PXD101 synergises with 5-fluorouracil to inhibit colon cancer cell growth in vitro and in vivo.
    Tumber A; Collins LS; Petersen KD; Thougaard A; Christiansen SJ; Dejligbjerg M; Jensen PB; Sehested M; Ritchie JW
    Cancer Chemother Pharmacol; 2007 Jul; 60(2):275-83. PubMed ID: 17124594
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Cytotoxicity of cantharidin analogues targeting protein phosphatase 2A.
    Shan HB; Cai YC; Liu Y; Zeng WN; Chen HX; Fan BT; Liu XH; Xu ZL; Wang B; Xian LJ
    Anticancer Drugs; 2006 Sep; 17(8):905-11. PubMed ID: 16940800
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Comparison of thymidylate synthase (TS) protein up-regulation after exposure to TS inhibitors in normal and tumor cell lines and tissues.
    Welsh SJ; Titley J; Brunton L; Valenti M; Monaghan P; Jackman AL; Aherne GW
    Clin Cancer Res; 2000 Jun; 6(6):2538-46. PubMed ID: 10873110
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Sequence-dependent antitumor effects of differentiation agents in combination with cell cycle-dependent cytotoxic drugs.
    Verheul HM; Qian DZ; Carducci MA; Pili R
    Cancer Chemother Pharmacol; 2007 Aug; 60(3):329-39. PubMed ID: 17256134
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Interferon-gamma-induced sensitization of colon carcinomas to ZD9331 targets caspases, downstream of Fas, independent of mitochondrial signaling and the inhibitor of apoptosis survivin.
    Geller J; Petak I; Szucs KS; Nagy K; Tillman DM; Houghton JA
    Clin Cancer Res; 2003 Dec; 9(17):6504-15. PubMed ID: 14695155
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Enhanced antitumor activity of 5-fluorouracil in combination with 2'-deoxyinosine in human colorectal cell lines and human colon tumor xenografts.
    Ciccolini J; Peillard L; Evrard A; Cuq P; Aubert C; Pelegrin A; Formento P; Milano G; Catalin J
    Clin Cancer Res; 2000 Apr; 6(4):1529-35. PubMed ID: 10778986
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Inhibition of thymidylate synthase activity by antisense oligodeoxynucleotide and possible role in thymineless treatment.
    Lin SB; Ts'o PO; Sun SK; Choo KB; Yang FY; Lim YP; Tsai HL; Au LC
    Mol Pharmacol; 2001 Sep; 60(3):474-9. PubMed ID: 11502877
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Inhibition of G1/S transition potentiates oxaliplatin-induced cell death in colon cancer cell lines.
    Rakitina TV; Vasilevskaya IA; O'Dwyer PJ
    Biochem Pharmacol; 2007 Jun; 73(11):1715-26. PubMed ID: 17343830
    [TBL] [Abstract][Full Text] [Related]  

  • 39. In vitro schedule-dependent interaction between paclitaxel and oxaliplatin in human cancer cell lines.
    Tanaka R; Ariyama H; Qin B; Takii Y; Baba E; Mitsugi K; Harada M; Nakano S
    Cancer Chemother Pharmacol; 2005 Jun; 55(6):595-601. PubMed ID: 15731917
    [TBL] [Abstract][Full Text] [Related]  

  • 40. DNA damage signaling in response to 5-fluorouracil in three colorectal cancer cell lines with different mismatch repair and TP53 status.
    Adamsen BL; Kravik KL; De Angelis PM
    Int J Oncol; 2011 Sep; 39(3):673-82. PubMed ID: 21674128
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 16.