BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

233 related articles for article (PubMed ID: 14653992)

  • 1. PLD1 regulates mTOR signaling and mediates Cdc42 activation of S6K1.
    Fang Y; Park IH; Wu AL; Du G; Huang P; Frohman MA; Walker SJ; Brown HA; Chen J
    Curr Biol; 2003 Dec; 13(23):2037-44. PubMed ID: 14653992
    [TBL] [Abstract][Full Text] [Related]  

  • 2. TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function.
    Schalm SS; Fingar DC; Sabatini DM; Blenis J
    Curr Biol; 2003 May; 13(10):797-806. PubMed ID: 12747827
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of a conserved motif required for mTOR signaling.
    Schalm SS; Blenis J
    Curr Biol; 2002 Apr; 12(8):632-9. PubMed ID: 11967149
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of phospholipase D1 in the regulation of mTOR activity by lysophosphatidic acid.
    Kam Y; Exton JH
    FASEB J; 2004 Feb; 18(2):311-9. PubMed ID: 14769825
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Chronic paraplegia-induced muscle atrophy downregulates the mTOR/S6K1 signaling pathway.
    Dreyer HC; Glynn EL; Lujan HL; Fry CS; DiCarlo SE; Rasmussen BB
    J Appl Physiol (1985); 2008 Jan; 104(1):27-33. PubMed ID: 17885021
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Distinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4E-binding proteins.
    Wang X; Beugnet A; Murakami M; Yamanaka S; Proud CG
    Mol Cell Biol; 2005 Apr; 25(7):2558-72. PubMed ID: 15767663
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rapamycin inhibits cell motility by suppression of mTOR-mediated S6K1 and 4E-BP1 pathways.
    Liu L; Li F; Cardelli JA; Martin KA; Blenis J; Huang S
    Oncogene; 2006 Nov; 25(53):7029-40. PubMed ID: 16715128
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Glucagon represses signaling through the mammalian target of rapamycin in rat liver by activating AMP-activated protein kinase.
    Kimball SR; Siegfried BA; Jefferson LS
    J Biol Chem; 2004 Dec; 279(52):54103-9. PubMed ID: 15494402
    [TBL] [Abstract][Full Text] [Related]  

  • 9. mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E.
    Fingar DC; Richardson CJ; Tee AR; Cheatham L; Tsou C; Blenis J
    Mol Cell Biol; 2004 Jan; 24(1):200-16. PubMed ID: 14673156
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Endotoxin disrupts the leucine-signaling pathway involving phosphorylation of mTOR, 4E-BP1, and S6K1 in skeletal muscle.
    Lang CH; Frost RA
    J Cell Physiol; 2005 Apr; 203(1):144-55. PubMed ID: 15389631
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E.
    Fingar DC; Salama S; Tsou C; Harlow E; Blenis J
    Genes Dev; 2002 Jun; 16(12):1472-87. PubMed ID: 12080086
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Rotenone induction of hydrogen peroxide inhibits mTOR-mediated S6K1 and 4E-BP1/eIF4E pathways, leading to neuronal apoptosis.
    Zhou Q; Liu C; Liu W; Zhang H; Zhang R; Liu J; Zhang J; Xu C; Liu L; Huang S; Chen L
    Toxicol Sci; 2015 Jan; 143(1):81-96. PubMed ID: 25304210
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Prolactin activates mammalian target-of-rapamycin through phosphatidylinositol 3-kinase and stimulates phosphorylation of p70S6K and 4E-binding protein-1 in lymphoma cells.
    Bishop JD; Nien WL; Dauphinee SM; Too CK
    J Endocrinol; 2006 Aug; 190(2):307-12. PubMed ID: 16899564
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Negative regulation of melanogenesis by phospholipase D1 through mTOR/p70 S6 kinase 1 signaling in mouse B16 melanoma cells.
    Ohguchi K; Banno Y; Nakagawa Y; Akao Y; Nozawa Y
    J Cell Physiol; 2005 Dec; 205(3):444-51. PubMed ID: 15895362
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Activation of AMPK and inactivation of Akt result in suppression of mTOR-mediated S6K1 and 4E-BP1 pathways leading to neuronal cell death in in vitro models of Parkinson's disease.
    Xu Y; Liu C; Chen S; Ye Y; Guo M; Ren Q; Liu L; Zhang H; Xu C; Zhou Q; Huang S; Chen L
    Cell Signal; 2014 Aug; 26(8):1680-1689. PubMed ID: 24726895
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phospholipase D2-derived phosphatidic acid binds to and activates ribosomal p70 S6 kinase independently of mTOR.
    Lehman N; Ledford B; Di Fulvio M; Frondorf K; McPhail LC; Gomez-Cambronero J
    FASEB J; 2007 Apr; 21(4):1075-87. PubMed ID: 17242159
    [TBL] [Abstract][Full Text] [Related]  

  • 17. S6K1 regulates hematopoietic stem cell self-renewal and leukemia maintenance.
    Ghosh J; Kobayashi M; Ramdas B; Chatterjee A; Ma P; Mali RS; Carlesso N; Liu Y; Plas DR; Chan RJ; Kapur R
    J Clin Invest; 2016 Jul; 126(7):2621-5. PubMed ID: 27294524
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability.
    Beugnet A; Tee AR; Taylor PM; Proud CG
    Biochem J; 2003 Jun; 372(Pt 2):555-66. PubMed ID: 12611592
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nutrient-dependent multimerization of the mammalian target of rapamycin through the N-terminal HEAT repeat region.
    Takahara T; Hara K; Yonezawa K; Sorimachi H; Maeda T
    J Biol Chem; 2006 Sep; 281(39):28605-14. PubMed ID: 16870609
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Alcohol impairs leucine-mediated phosphorylation of 4E-BP1, S6K1, eIF4G, and mTOR in skeletal muscle.
    Lang CH; Frost RA; Deshpande N; Kumar V; Vary TC; Jefferson LS; Kimball SR
    Am J Physiol Endocrinol Metab; 2003 Dec; 285(6):E1205-15. PubMed ID: 12944322
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.