BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 14654783)

  • 1. Functional role of Mdm2 phosphorylation by ATR in attenuation of p53 nuclear export.
    Shinozaki T; Nota A; Taya Y; Okamoto K
    Oncogene; 2003 Dec; 22(55):8870-80. PubMed ID: 14654783
    [TBL] [Abstract][Full Text] [Related]  

  • 2. ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage.
    Maya R; Balass M; Kim ST; Shkedy D; Leal JF; Shifman O; Moas M; Buschmann T; Ronai Z; Shiloh Y; Kastan MB; Katzir E; Oren M
    Genes Dev; 2001 May; 15(9):1067-77. PubMed ID: 11331603
    [TBL] [Abstract][Full Text] [Related]  

  • 3. HMG-CoA reductase inhibitors, statins, induce phosphorylation of Mdm2 and attenuate the p53 response to DNA damage.
    Pääjärvi G; Roudier E; Crisby M; Högberg J; Stenius U
    FASEB J; 2005 Mar; 19(3):476-8. PubMed ID: 15625077
    [TBL] [Abstract][Full Text] [Related]  

  • 4. ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage.
    Chen L; Gilkes DM; Pan Y; Lane WS; Chen J
    EMBO J; 2005 Oct; 24(19):3411-22. PubMed ID: 16163388
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PML regulates p53 stability by sequestering Mdm2 to the nucleolus.
    Bernardi R; Scaglioni PP; Bergmann S; Horn HF; Vousden KH; Pandolfi PP
    Nat Cell Biol; 2004 Jul; 6(7):665-72. PubMed ID: 15195100
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage.
    Khosravi R; Maya R; Gottlieb T; Oren M; Shiloh Y; Shkedy D
    Proc Natl Acad Sci U S A; 1999 Dec; 96(26):14973-7. PubMed ID: 10611322
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus.
    Mayo LD; Donner DB
    Proc Natl Acad Sci U S A; 2001 Sep; 98(20):11598-603. PubMed ID: 11504915
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Nitric oxide promotes p53 nuclear retention and sensitizes neuroblastoma cells to apoptosis by ionizing radiation.
    Wang X; Zalcenstein A; Oren M
    Cell Death Differ; 2003 Apr; 10(4):468-76. PubMed ID: 12719724
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Critical roles for the serine 20, but not the serine 15, phosphorylation site and for the polyproline domain in regulating p53 turnover.
    Dumaz N; Milne DM; Jardine LJ; Meek DW
    Biochem J; 2001 Oct; 359(Pt 2):459-64. PubMed ID: 11583595
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The carboxy-terminal serine 392 phosphorylation site of human p53 is not required for wild-type activities.
    Fiscella M; Zambrano N; Ullrich SJ; Unger T; Lin D; Cho B; Mercer WE; Anderson CW; Appella E
    Oncogene; 1994 Nov; 9(11):3249-57. PubMed ID: 7936649
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulation.
    Goldberg Z; Vogt Sionov R; Berger M; Zwang Y; Perets R; Van Etten RA; Oren M; Taya Y; Haupt Y
    EMBO J; 2002 Jul; 21(14):3715-27. PubMed ID: 12110584
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Molecular interaction map of the p53 and Mdm2 logic elements, which control the Off-On switch of p53 in response to DNA damage.
    Kohn KW; Pommier Y
    Biochem Biophys Res Commun; 2005 Jun; 331(3):816-27. PubMed ID: 15865937
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage.
    Pereg Y; Shkedy D; de Graaf P; Meulmeester E; Edelson-Averbukh M; Salek M; Biton S; Teunisse AF; Lehmann WD; Jochemsen AG; Shiloh Y
    Proc Natl Acad Sci U S A; 2005 Apr; 102(14):5056-61. PubMed ID: 15788536
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phosphorylation of Daxx by ATM contributes to DNA damage-induced p53 activation.
    Tang J; Agrawal T; Cheng Q; Qu L; Brewer MD; Chen J; Yang X
    PLoS One; 2013; 8(2):e55813. PubMed ID: 23405218
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Indole-3-carbinol activates the ATM signaling pathway independent of DNA damage to stabilize p53 and induce G1 arrest of human mammary epithelial cells.
    Brew CT; Aronchik I; Hsu JC; Sheen JH; Dickson RB; Bjeldanes LF; Firestone GL
    Int J Cancer; 2006 Feb; 118(4):857-68. PubMed ID: 16152627
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DNA damage-induced phosphorylation of MdmX at serine 367 activates p53 by targeting MdmX for Mdm2-dependent degradation.
    Okamoto K; Kashima K; Pereg Y; Ishida M; Yamazaki S; Nota A; Teunisse A; Migliorini D; Kitabayashi I; Marine JC; Prives C; Shiloh Y; Jochemsen AG; Taya Y
    Mol Cell Biol; 2005 Nov; 25(21):9608-20. PubMed ID: 16227609
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Comparison of hypoxia-induced replication arrest with hydroxyurea and aphidicolin-induced arrest.
    Hammond EM; Green SL; Giaccia AJ
    Mutat Res; 2003 Nov; 532(1-2):205-13. PubMed ID: 14643437
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The ataxia-telangiectasia related protein ATR mediates DNA-dependent phosphorylation of p53.
    Lakin ND; Hann BC; Jackson SP
    Oncogene; 1999 Jul; 18(27):3989-95. PubMed ID: 10435622
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A p53 amino-terminal nuclear export signal inhibited by DNA damage-induced phosphorylation.
    Zhang Y; Xiong Y
    Science; 2001 Jun; 292(5523):1910-5. PubMed ID: 11397945
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.
    Honda R; Yasuda H
    EMBO J; 1999 Jan; 18(1):22-7. PubMed ID: 9878046
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.