These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

438 related articles for article (PubMed ID: 14654982)

  • 1. Intracellular domain generation of amyloid precursor protein by epsilon-cleavage depends on C-terminal fragment by alpha-secretase cleavage.
    Kume H; Maruyama K; Kametani F
    Int J Mol Med; 2004 Jan; 13(1):121-5. PubMed ID: 14654982
    [TBL] [Abstract][Full Text] [Related]  

  • 2. APPepsilon, the epsilon-secretase-derived N-terminal product of the beta-amyloid precursor protein, behaves as a type I protein and undergoes alpha-, beta-, and gamma-secretase cleavages.
    Lefranc-Jullien S; Sunyach C; Checler F
    J Neurochem; 2006 May; 97(3):807-17. PubMed ID: 16524370
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Abeta 11-40/42 production without gamma-secretase epsilon-site cleavage.
    Kume H; Kametani F
    Biochem Biophys Res Commun; 2006 Nov; 349(4):1356-60. PubMed ID: 16979587
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
    Evin G; Zhu A; Holsinger RM; Masters CL; Li QX
    J Neurosci Res; 2003 Nov; 74(3):386-92. PubMed ID: 14598315
    [TBL] [Abstract][Full Text] [Related]  

  • 5. gamma-Secretase can cleave amyloid precursor protein fragments independent of alpha- and beta-secretase pre-cutting.
    Kume H; Sekijima Y; Maruyama K; Kametani F
    Int J Mol Med; 2003 Jul; 12(1):57-60. PubMed ID: 12792809
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Secretion of long Abeta-related peptides processed at epsilon-cleavage site is dependent on the alpha-secretase pre-cutting.
    Kametani F
    FEBS Lett; 2004 Jul; 570(1-3):73-6. PubMed ID: 15251442
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphorylation of amyloid precursor carboxy-terminal fragments enhances their processing by a gamma-secretase-dependent mechanism.
    Vingtdeux V; Hamdane M; Gompel M; Bégard S; Drobecq H; Ghestem A; Grosjean ME; Kostanjevecki V; Grognet P; Vanmechelen E; Buée L; Delacourte A; Sergeant N
    Neurobiol Dis; 2005 Nov; 20(2):625-37. PubMed ID: 15936948
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In vitro gamma-secretase cleavage of the Alzheimer's amyloid precursor protein correlates to a subset of presenilin complexes and is inhibited by zinc.
    Hoke DE; Tan JL; Ilaya NT; Culvenor JG; Smith SJ; White AR; Masters CL; Evin GM
    FEBS J; 2005 Nov; 272(21):5544-57. PubMed ID: 16262694
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Purification and cloning of amyloid precursor protein beta-secretase from human brain.
    Sinha S; Anderson JP; Barbour R; Basi GS; Caccavello R; Davis D; Doan M; Dovey HF; Frigon N; Hong J; Jacobson-Croak K; Jewett N; Keim P; Knops J; Lieberburg I; Power M; Tan H; Tatsuno G; Tung J; Schenk D; Seubert P; Suomensaari SM; Wang S; Walker D; Zhao J; McConlogue L; John V
    Nature; 1999 Dec; 402(6761):537-40. PubMed ID: 10591214
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mutations in the transmembrane domain of APP altering gamma-secretase specificity.
    Lichtenthaler SF; Ida N; Multhaup G; Masters CL; Beyreuther K
    Biochemistry; 1997 Dec; 36(49):15396-403. PubMed ID: 9398269
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Proteasome-mediated degradation of the C-terminus of the Alzheimer's disease beta-amyloid protein precursor: effect of C-terminal truncation on production of beta-amyloid protein.
    Nunan J; Williamson NA; Hill AF; Sernee MF; Masters CL; Small DH
    J Neurosci Res; 2003 Nov; 74(3):378-85. PubMed ID: 14598314
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Familial Alzheimer's disease mutations inhibit gamma-secretase-mediated liberation of beta-amyloid precursor protein carboxy-terminal fragment.
    Wiley JC; Hudson M; Kanning KC; Schecterson LC; Bothwell M
    J Neurochem; 2005 Sep; 94(5):1189-201. PubMed ID: 15992373
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Processing of the Alzheimer's disease amyloid precursor protein in Pichia pastoris: immunodetection of alpha-, beta-, and gamma-secretase products.
    Le Brocque D; Henry A; Cappai R; Li QX; Tanner JE; Galatis D; Gray C; Holmes S; Underwood JR; Beyreuther K; Masters CL; Evin G
    Biochemistry; 1998 Oct; 37(42):14958-65. PubMed ID: 9778373
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

  • 15. APP substitutions V715F and L720P alter PS1 conformation and differentially affect Abeta and AICD generation.
    Tesco G; Ginestroni A; Hiltunen M; Kim M; Dolios G; Hyman BT; Wang R; Berezovska O; Tanzi RE
    J Neurochem; 2005 Oct; 95(2):446-56. PubMed ID: 16086682
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutations in APP have independent effects on Abeta and CTFgamma generation.
    Hecimovic S; Wang J; Dolios G; Martinez M; Wang R; Goate AM
    Neurobiol Dis; 2004 Nov; 17(2):205-18. PubMed ID: 15474359
    [TBL] [Abstract][Full Text] [Related]  

  • 17. gamma-Secretase cleavage and binding to FE65 regulate the nuclear translocation of the intracellular C-terminal domain (ICD) of the APP family of proteins.
    Walsh DM; Fadeeva JV; LaVoie MJ; Paliga K; Eggert S; Kimberly WT; Wasco W; Selkoe DJ
    Biochemistry; 2003 Jun; 42(22):6664-73. PubMed ID: 12779321
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Truncated carboxyl-terminal fragments of beta-amyloid precursor protein are processed to amyloid beta-proteins 40 and 42.
    Funamoto S; Morishima-Kawashima M; Tanimura Y; Hirotani N; Saido TC; Ihara Y
    Biochemistry; 2004 Oct; 43(42):13532-40. PubMed ID: 15491160
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Intracellular pH regulates amyloid precursor protein intracellular domain accumulation.
    Vingtdeux V; Hamdane M; Bégard S; Loyens A; Delacourte A; Beauvillain JC; Buée L; Marambaud P; Sergeant N
    Neurobiol Dis; 2007 Mar; 25(3):686-96. PubMed ID: 17207630
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity.
    Yan R; Bienkowski MJ; Shuck ME; Miao H; Tory MC; Pauley AM; Brashier JR; Stratman NC; Mathews WR; Buhl AE; Carter DB; Tomasselli AG; Parodi LA; Heinrikson RL; Gurney ME
    Nature; 1999 Dec; 402(6761):533-7. PubMed ID: 10591213
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.