BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 14657349)

  • 1. MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation.
    Wang Y; Qin J
    Proc Natl Acad Sci U S A; 2003 Dec; 100(26):15387-92. PubMed ID: 14657349
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The alkylating carcinogen N-methyl-N'-nitro-N-nitrosoguanidine activates the plasminogen activator inhibitor-1 gene through sequential phosphorylation of p53 by ATM and ATR kinases.
    Vidal B; Parra M; Jardí M; Saito S; Appella E; Muñoz-Cánoves P
    Thromb Haemost; 2005 Mar; 93(3):584-91. PubMed ID: 15735814
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase.
    Stojic L; Mojas N; Cejka P; Di Pietro M; Ferrari S; Marra G; Jiricny J
    Genes Dev; 2004 Jun; 18(11):1331-44. PubMed ID: 15175264
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Methylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2.
    Adamson AW; Beardsley DI; Kim WJ; Gao Y; Baskaran R; Brown KD
    Mol Biol Cell; 2005 Mar; 16(3):1513-26. PubMed ID: 15647386
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The mismatch repair system is required for S-phase checkpoint activation.
    Brown KD; Rathi A; Kamath R; Beardsley DI; Zhan Q; Mannino JL; Baskaran R
    Nat Genet; 2003 Jan; 33(1):80-4. PubMed ID: 12447371
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphorylation of serines 635 and 645 of human Rad17 is cell cycle regulated and is required for G(1)/S checkpoint activation in response to DNA damage.
    Post S; Weng YC; Cimprich K; Chen LB; Xu Y; Lee EY
    Proc Natl Acad Sci U S A; 2001 Nov; 98(23):13102-7. PubMed ID: 11687627
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Interactions of human mismatch repair proteins MutSalpha and MutLalpha with proteins of the ATR-Chk1 pathway.
    Liu Y; Fang Y; Shao H; Lindsey-Boltz L; Sancar A; Modrich P
    J Biol Chem; 2010 Feb; 285(8):5974-82. PubMed ID: 20029092
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ATR regulates hexavalent chromium-induced S-phase checkpoint through phosphorylation of SMC1.
    Wakeman TP; Xu B
    Mutat Res; 2006 Nov; 610(1-2):14-20. PubMed ID: 16876463
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ATR-CHK1-E2F3 signaling transactivates human ribonucleotide reductase small subunit M2 for DNA repair induced by the chemical carcinogen MNNG.
    Gong C; Liu H; Song R; Zhong T; Lou M; Wang T; Qi H; Shen J; Zhu L; Shao J
    Biochim Biophys Acta; 2016 Apr; 1859(4):612-26. PubMed ID: 26921499
    [TBL] [Abstract][Full Text] [Related]  

  • 10. MLH1- and ATM-dependent MAPK signaling is activated through c-Abl in response to the alkylator N-methyl-N'-nitro-N'-nitrosoguanidine.
    Kim WJ; Rajasekaran B; Brown KD
    J Biol Chem; 2007 Nov; 282(44):32021-31. PubMed ID: 17804421
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phosphorylation of nucleotide excision repair factor xeroderma pigmentosum group A by ataxia telangiectasia mutated and Rad3-related-dependent checkpoint pathway promotes cell survival in response to UV irradiation.
    Wu X; Shell SM; Yang Z; Zou Y
    Cancer Res; 2006 Mar; 66(6):2997-3005. PubMed ID: 16540648
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Human Rad9 is required for the activation of S-phase checkpoint and the maintenance of chromosomal stability.
    Dang T; Bao S; Wang XF
    Genes Cells; 2005 Apr; 10(4):287-95. PubMed ID: 15773892
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Replication protein A2 phosphorylation after DNA damage by the coordinated action of ataxia telangiectasia-mutated and DNA-dependent protein kinase.
    Wang H; Guan J; Wang H; Perrault AR; Wang Y; Iliakis G
    Cancer Res; 2001 Dec; 61(23):8554-63. PubMed ID: 11731442
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The ATM-dependent DNA damage signaling pathway.
    Kitagawa R; Kastan MB
    Cold Spring Harb Symp Quant Biol; 2005; 70():99-109. PubMed ID: 16869743
    [TBL] [Abstract][Full Text] [Related]  

  • 15. hMSH2 recruits ATR to DNA damage sites for activation during DNA damage-induced apoptosis.
    Pabla N; Ma Z; McIlhatton MA; Fishel R; Dong Z
    J Biol Chem; 2011 Mar; 286(12):10411-8. PubMed ID: 21285353
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin.
    Zou L; Cortez D; Elledge SJ
    Genes Dev; 2002 Jan; 16(2):198-208. PubMed ID: 11799063
    [TBL] [Abstract][Full Text] [Related]  

  • 17. N-methyl-N'-nitro-N-nitrosoguanidine activates cell-cycle arrest through distinct mechanisms activated in a dose-dependent manner.
    Beardsley DI; Kim WJ; Brown KD
    Mol Pharmacol; 2005 Oct; 68(4):1049-60. PubMed ID: 15994368
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Exonuclease 1 (Exo1) is required for activating response to S(N)1 DNA methylating agents.
    Izumchenko E; Saydi J; Brown KD
    DNA Repair (Amst); 2012 Dec; 11(12):951-64. PubMed ID: 23062884
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ATR-dependent phosphorylation of DNA-dependent protein kinase catalytic subunit in response to UV-induced replication stress.
    Yajima H; Lee KJ; Chen BP
    Mol Cell Biol; 2006 Oct; 26(20):7520-8. PubMed ID: 16908529
    [TBL] [Abstract][Full Text] [Related]  

  • 20. ATR and ATRIP: partners in checkpoint signaling.
    Cortez D; Guntuku S; Qin J; Elledge SJ
    Science; 2001 Nov; 294(5547):1713-6. PubMed ID: 11721054
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.