176 related articles for article (PubMed ID: 14661061)
1. SU11752 inhibits the DNA-dependent protein kinase and DNA double-strand break repair resulting in ionizing radiation sensitization.
Ismail IH; Mårtensson S; Moshinsky D; Rice A; Tang C; Howlett A; McMahon G; Hammarsten O
Oncogene; 2004 Jan; 23(4):873-82. PubMed ID: 14661061
[TBL] [Abstract][Full Text] [Related]
2. Wortmannin sensitizes mammalian cells to radiation by inhibiting the DNA-dependent protein kinase-mediated rejoining of double-strand breaks.
Chernikova SB; Wells RL; Elkind MM
Radiat Res; 1999 Feb; 151(2):159-66. PubMed ID: 9952300
[TBL] [Abstract][Full Text] [Related]
3. A targeted inhibition of DNA-dependent protein kinase sensitizes breast cancer cells following ionizing radiation.
Kim CH; Park SJ; Lee SH
J Pharmacol Exp Ther; 2002 Nov; 303(2):753-9. PubMed ID: 12388662
[TBL] [Abstract][Full Text] [Related]
4. Radiosensitization and DNA repair inhibition by the combined use of novel inhibitors of DNA-dependent protein kinase and poly(ADP-ribose) polymerase-1.
Veuger SJ; Curtin NJ; Richardson CJ; Smith GC; Durkacz BW
Cancer Res; 2003 Sep; 63(18):6008-15. PubMed ID: 14522929
[TBL] [Abstract][Full Text] [Related]
5. Interactive competition between homologous recombination and non-homologous end joining.
Allen C; Halbrook J; Nickoloff JA
Mol Cancer Res; 2003 Oct; 1(12):913-20. PubMed ID: 14573792
[TBL] [Abstract][Full Text] [Related]
6. [DNA-dependent protein kinase: a major protein involved in the cellular response to ionizing radiation].
Muller C; Rodrigo G; Calsou P; Salles B
Bull Cancer; 1999 Dec; 86(12):977-83. PubMed ID: 10660692
[TBL] [Abstract][Full Text] [Related]
7. Nonhomologous end-joining of ionizing radiation-induced DNA double-stranded breaks in human tumor cells deficient in BRCA1 or BRCA2.
Wang H; Zeng ZC; Bui TA; DiBiase SJ; Qin W; Xia F; Powell SN; Iliakis G
Cancer Res; 2001 Jan; 61(1):270-7. PubMed ID: 11196174
[TBL] [Abstract][Full Text] [Related]
8. DNA-dependent protein kinase is a molecular target for the development of noncytotoxic radiation-sensitizing drugs.
Shinohara ET; Geng L; Tan J; Chen H; Shir Y; Edwards E; Halbrook J; Kesicki EA; Kashishian A; Hallahan DE
Cancer Res; 2005 Jun; 65(12):4987-92. PubMed ID: 15958537
[TBL] [Abstract][Full Text] [Related]
9. Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin.
Sarkaria JN; Tibbetts RS; Busby EC; Kennedy AP; Hill DE; Abraham RT
Cancer Res; 1998 Oct; 58(19):4375-82. PubMed ID: 9766667
[TBL] [Abstract][Full Text] [Related]
10. Threonines 2638/2647 in DNA-PK are essential for cellular resistance to ionizing radiation.
Soubeyrand S; Pope L; Pakuts B; Haché RJ
Cancer Res; 2003 Mar; 63(6):1198-201. PubMed ID: 12649176
[TBL] [Abstract][Full Text] [Related]
11. Potentiation of chlorambucil cytotoxicity in B-cell chronic lymphocytic leukemia by inhibition of DNA-dependent protein kinase activity using wortmannin.
Christodoulopoulos G; Muller C; Salles B; Kazmi R; Panasci L
Cancer Res; 1998 May; 58(9):1789-92. PubMed ID: 9581813
[TBL] [Abstract][Full Text] [Related]
12. Selective inactivation of DNA-dependent protein kinase with antisense oligodeoxynucleotides: consequences for the rejoining of radiation-induced DNA double-strand breaks and radiosensitivity of human cancer cell lines.
Sak A; Stuschke M; Wurm R; Schroeder G; Sinn B; Wolf G; Budach V
Cancer Res; 2002 Nov; 62(22):6621-4. PubMed ID: 12438258
[TBL] [Abstract][Full Text] [Related]
13. Interaction of DNA-dependent protein kinase and poly(ADP-ribose) polymerase with radiation-induced DNA strand breaks.
Weinfeld M; Chaudhry MA; D'Amours D; Pelletier JD; Poirier GG; Povirk LF; Lees-Miller SP
Radiat Res; 1997 Jul; 148(1):22-8. PubMed ID: 9216614
[TBL] [Abstract][Full Text] [Related]
14. Backup pathways of NHEJ are suppressed by DNA-PK.
Perrault R; Wang H; Wang M; Rosidi B; Iliakis G
J Cell Biochem; 2004 Jul; 92(4):781-94. PubMed ID: 15211575
[TBL] [Abstract][Full Text] [Related]
15. Trifluoperazine stimulates ionizing radiation induced cell killing through inhibition of DNA repair.
Gangopadhyay S; Karmakar P; Dasgupta U; Chakraborty A
Mutat Res; 2007 Oct; 633(2):117-25. PubMed ID: 17627868
[TBL] [Abstract][Full Text] [Related]
16. The DNA repair complex DNA-PK, a pharmacological target in cancer chemotherapy and radiotherapy.
Salles B; Calsou P; Frit P; Muller C
Pathol Biol (Paris); 2006 May; 54(4):185-93. PubMed ID: 16563661
[TBL] [Abstract][Full Text] [Related]
17. [Repair of ionizing radiation induced DNA double strand breaks].
Widłak P
Postepy Hig Med Dosw; 2000; 54(2):133-48. PubMed ID: 10857377
[TBL] [Abstract][Full Text] [Related]
18. Identification of a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (NU7441) by screening of chromenone libraries.
Leahy JJ; Golding BT; Griffin RJ; Hardcastle IR; Richardson C; Rigoreau L; Smith GC
Bioorg Med Chem Lett; 2004 Dec; 14(24):6083-7. PubMed ID: 15546735
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of hsp90 compromises the DNA damage response to radiation.
Dote H; Burgan WE; Camphausen K; Tofilon PJ
Cancer Res; 2006 Sep; 66(18):9211-20. PubMed ID: 16982765
[TBL] [Abstract][Full Text] [Related]
20. Wortmannin inhibits repair of DNA double-strand breaks in irradiated normal human cells.
Okayasu R; Suetomi K; Ullrich RL
Radiat Res; 1998 May; 149(5):440-5. PubMed ID: 9588354
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
