BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

125 related articles for article (PubMed ID: 14661983)

  • 1. Interstrand cross-linking of DNA by FK317 and its deacetylated metabolites FR70496 and FR157471.
    Williams RM; Ducept P
    Biochemistry; 2003 Dec; 42(49):14696-701. PubMed ID: 14661983
    [TBL] [Abstract][Full Text] [Related]  

  • 2. FR900482, a close cousin of mitomycin C that exploits mitosene-based DNA cross-linking.
    Williams RM; Rajski SR; Rollins SB
    Chem Biol; 1997 Feb; 4(2):127-37. PubMed ID: 9190287
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Interstrand DNA-DNA and DNA-protein cross-links by a new antitumor antibiotic, FK973, in L1210 cells.
    Masuda K; Nakamura T; Mizota T; Mori J; Shimomura K
    Cancer Res; 1988 Sep; 48(18):5172-7. PubMed ID: 3409243
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Highly efficient sequence-specific DNA interstrand cross-linking by pyrrole/imidazole CPI conjugates.
    Bando T; Narita A; Saito I; Sugiyama H
    J Am Chem Soc; 2003 Mar; 125(12):3471-85. PubMed ID: 12643709
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Unique properties of DNA interstrand cross-links of antitumor oxaliplatin and the effect of chirality of the carrier ligand.
    Kasparkova J; Vojtiskova M; Natile G; Brabec V
    Chemistry; 2008; 14(4):1330-41. PubMed ID: 18022972
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cytotoxic mechanisms of FK317, a new class of bioreductive agent with potent antitumor activity.
    Naoe Y; Inami M; Kawamura I; Nishigaki F; Tsujimoto S; Matsumoto S; Manda T; Shimomura K
    Jpn J Cancer Res; 1998 Jun; 89(6):666-72. PubMed ID: 9703365
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Reaching for the other side: generating sequence-dependent interstrand cross-links with 5-bromodeoxyuridine and gamma-rays.
    Dextraze ME; Cecchini S; Bergeron F; Girouard S; Turcotte K; Wagner JR; Hunting DJ
    Biochemistry; 2009 Mar; 48(9):2005-11. PubMed ID: 19216505
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DNA interstrand cross-links from modified nucleotides: mechanism and application.
    Greenberg MM
    Nucleic Acids Symp Ser (Oxf); 2005; (49):57-8. PubMed ID: 17150631
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure, flexibility, and repair of two different orientations of the same alkyl interstrand DNA cross-link.
    Noll DM; Webba da Silva M; Noronha AM; Wilds CJ; Colvin OM; Gamcsik MP; Miller PS
    Biochemistry; 2005 May; 44(18):6764-75. PubMed ID: 15865422
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The pyrrolobenzodiazepine dimer SJG-136 forms sequence-dependent intrastrand DNA cross-links and monoalkylated adducts in addition to interstrand cross-links.
    Rahman KM; Thompson AS; James CH; Narayanaswamy M; Thurston DE
    J Am Chem Soc; 2009 Sep; 131(38):13756-66. PubMed ID: 19725510
    [TBL] [Abstract][Full Text] [Related]  

  • 11. FR900482 class of anti-tumor drugs cross-links oncoprotein HMG I/Y to DNA in vivo.
    Beckerbauer L; Tepe JJ; Cullison J; Reeves R; Williams RM
    Chem Biol; 2000 Oct; 7(10):805-12. PubMed ID: 11033083
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DNA cross-linking patterns induced by an antitumor-active trinuclear platinum complex and comparison with its dinuclear analogue.
    Zhu J; Zhao Y; Zhu Y; Wu Z; Lin M; He W; Wang Y; Chen G; Dong L; Zhang J; Lu Y; Guo Z
    Chemistry; 2009; 15(21):5245-53. PubMed ID: 19350599
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sequence preferences of DNA interstrand crosslinking agents: quantitation of interstrand crosslink locations in DNA duplex fragments containing multiple crosslinkable sites.
    Millard JT; Weidner MF; Kirchner JJ; Ribeiro S; Hopkins PB
    Nucleic Acids Res; 1991 Apr; 19(8):1885-91. PubMed ID: 1903204
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Gamma-radiolysis and hydroxyl radical produce interstrand cross-links in DNA involving thymidine.
    Ding H; Greenberg MM
    Chem Res Toxicol; 2007 Nov; 20(11):1623-8. PubMed ID: 17939740
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Total synthesis of natural product DNA cross-linking agents.
    Coleman RS
    Curr Opin Drug Discov Devel; 2001 Jul; 4(4):435-49. PubMed ID: 11727309
    [TBL] [Abstract][Full Text] [Related]  

  • 16. SJG-136 (NSC 694501), a novel rationally designed DNA minor groove interstrand cross-linking agent with potent and broad spectrum antitumor activity: part 1: cellular pharmacology, in vitro and initial in vivo antitumor activity.
    Hartley JA; Spanswick VJ; Brooks N; Clingen PH; McHugh PJ; Hochhauser D; Pedley RB; Kelland LR; Alley MC; Schultz R; Hollingshead MG; Schweikart KM; Tomaszewski JE; Sausville EA; Gregson SJ; Howard PW; Thurston DE
    Cancer Res; 2004 Sep; 64(18):6693-9. PubMed ID: 15374986
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Sequence-selective interaction of the minor-groove interstrand cross-linking agent SJG-136 with naked and cellular DNA: footprinting and enzyme inhibition studies.
    Martin C; Ellis T; McGurk CJ; Jenkins TC; Hartley JA; Waring MJ; Thurston DE
    Biochemistry; 2005 Mar; 44(11):4135-47. PubMed ID: 15766241
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mitomycin dimers: polyfunctional cross-linkers of DNA.
    Paz MM; Kumar GS; Glover M; Waring MJ; Tomasz M
    J Med Chem; 2004 Jun; 47(12):3308-19. PubMed ID: 15163210
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural and function modification of DNA by mitomycin C. Mechanism of the DNA sequence specificity of mitomycins.
    Gargiulo D; Kumar GS; Musser SS; Tomasz M
    Nucleic Acids Symp Ser; 1995; (34):169-70. PubMed ID: 8841606
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 1,2,5,6-Diepoxyhexane and 1,2,7,8-diepoxyoctane cross-link duplex DNA at 5'-GNC sequences.
    Yunes MJ; Charnecki SE; Marden JJ; Millard JT
    Chem Res Toxicol; 1996 Sep; 9(6):994-1000. PubMed ID: 8870987
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.