121 related articles for article (PubMed ID: 14667226)
1. Parallel solid-phase synthesis and evaluation of inhibitors of Streptomyces coelicolor type II dehydroquinase.
González-Bello C; Lence E; Toscano MD; Castedo L; Coggins JR; Abell C
J Med Chem; 2003 Dec; 46(26):5735-44. PubMed ID: 14667226
[TBL] [Abstract][Full Text] [Related]
2. Nanomolar competitive inhibitors of Mycobacterium tuberculosis and Streptomyces coelicolor type II dehydroquinase.
Prazeres VF; Sánchez-Sixto C; Castedo L; Lamb H; Hawkins AR; Riboldi-Tunnicliffe A; Coggins JR; Lapthorn AJ; González-Bello C
ChemMedChem; 2007 Feb; 2(2):194-207. PubMed ID: 17245805
[TBL] [Abstract][Full Text] [Related]
3. Structure-based design, synthesis, and biological evaluation of inhibitors of Mycobacterium tuberculosis type II dehydroquinase.
Sánchez-Sixto C; Prazeres VF; Castedo L; Lamb H; Hawkins AR; González-Bello C
J Med Chem; 2005 Jul; 48(15):4871-81. PubMed ID: 16033267
[TBL] [Abstract][Full Text] [Related]
4. Competitive inhibitors of Helicobacter pylori type II dehydroquinase: synthesis, biological evaluation, and NMR studies.
Sánchez-Sixto C; Prazeres VF; Castedo L; Suh SW; Lamb H; Hawkins AR; Cañada FJ; Jiménez-Barbero J; González-Bello C
ChemMedChem; 2008 May; 3(5):756-70. PubMed ID: 18200648
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis and evaluation of bifunctional inhibitors of type II dehydroquinase.
Toscano MD; Frederickson M; Evans DP; Coggins JR; Abell C; González-Bello C
Org Biomol Chem; 2003 Jun; 1(12):2075-83. PubMed ID: 12945898
[TBL] [Abstract][Full Text] [Related]
6. Rational design of new bifunctional inhibitors of type II dehydroquinase.
Toscano MD; Stewart KA; Coggins JR; Lapthorn AJ; Abell C
Org Biomol Chem; 2005 Sep; 3(17):3102-4. PubMed ID: 16106291
[TBL] [Abstract][Full Text] [Related]
7. Crystal structures of Helicobacter pylori type II dehydroquinase inhibitor complexes: new directions for inhibitor design.
Robinson DA; Stewart KA; Price NC; Chalk PA; Coggins JR; Lapthorn AJ
J Med Chem; 2006 Feb; 49(4):1282-90. PubMed ID: 16480265
[TBL] [Abstract][Full Text] [Related]
8. Nanomolar inhibition of type II dehydroquinase based on the enolate reaction mechanism.
Toscano MD; Payne RJ; Chiba A; Kerbarh O; Abell C
ChemMedChem; 2007 Jan; 2(1):101-12. PubMed ID: 17068841
[TBL] [Abstract][Full Text] [Related]
9. Rational design, synthesis, and evaluation of nanomolar type II dehydroquinase inhibitors.
Payne RJ; Peyrot F; Kerbarh O; Abell AD; Abell C
ChemMedChem; 2007 Jul; 2(7):1015-29. PubMed ID: 17487900
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and biological evaluation of new nanomolar competitive inhibitors of Helicobacter pylori type II dehydroquinase. Structural details of the role of the aromatic moieties with essential residues.
Prazeres VF; Tizón L; Otero JM; Guardado-Calvo P; Llamas-Saiz AL; van Raaij MJ; Castedo L; Lamb H; Hawkins AR; González-Bello C
J Med Chem; 2010 Jan; 53(1):191-200. PubMed ID: 19911771
[TBL] [Abstract][Full Text] [Related]
11. Inhibitors of types I and II dehydroquinase.
Le Sann C; Gower MA; Abell AD
Mini Rev Med Chem; 2004 Sep; 4(7):747-56. PubMed ID: 15379642
[TBL] [Abstract][Full Text] [Related]
12. Understanding the key factors that control the inhibition of type II dehydroquinase by (2R)-2-benzyl-3-dehydroquinic acids.
Peón A; Otero JM; Tizón L; Prazeres VF; Llamas-Saiz AL; Fox GC; van Raaij MJ; Lamb H; Hawkins AR; Gago F; Castedo L; González-Bello C
ChemMedChem; 2010 Oct; 5(10):1726-33. PubMed ID: 20815012
[TBL] [Abstract][Full Text] [Related]
13. Evidence that the active site in type II dehydroquinase from Streptomyces coelicolor is near the single tryptophan.
Boam DJ; Price NC; Kelly SM; Krell T; Coggins JR
Biochem Soc Trans; 1997 Feb; 25(1):348; replaces 93S. PubMed ID: 9147947
[No Abstract] [Full Text] [Related]
14. Progress in type II dehydroquinase inhibitors: from concept to practice.
González-Bello C; Castedo L
Med Res Rev; 2007 Mar; 27(2):177-208. PubMed ID: 17004270
[TBL] [Abstract][Full Text] [Related]
15. Irreversible inhibition of type I dehydroquinase by substrates for type II dehydroquinase.
Bello CG; Harris JM; Manthey MK; Coggins JR; Abell C
Bioorg Med Chem Lett; 2000 Mar; 10(5):407-9. PubMed ID: 10743936
[TBL] [Abstract][Full Text] [Related]
16. The structure and mechanism of the type II dehydroquinase from Streptomyces coelicolor.
Roszak AW; Robinson DA; Krell T; Hunter IS; Fredrickson M; Abell C; Coggins JR; Lapthorn AJ
Structure; 2002 Apr; 10(4):493-503. PubMed ID: 11937054
[TBL] [Abstract][Full Text] [Related]
17. Differential inhibition of class I and class II 5-enolpyruvylshikimate-3-phosphate synthases by tetrahedral reaction intermediate analogues.
Funke T; Healy-Fried ML; Han H; Alberg DG; Bartlett PA; Schönbrunn E
Biochemistry; 2007 Nov; 46(46):13344-51. PubMed ID: 17958399
[TBL] [Abstract][Full Text] [Related]
18. 2-substituted-3-dehydroquinic acids as potent competitive inhibitors of type II dehydroquinase.
Prazeres VF; Castedo L; Lamb H; Hawkins AR; González-Bello C
ChemMedChem; 2009 Dec; 4(12):1980-4. PubMed ID: 19856378
[No Abstract] [Full Text] [Related]
19. (1R,4S,5R)-3-Fluoro-1,4,5-trihydroxy-2-cyclohexene-1-carboxylic acid: the fluoro analogue of the enolate intermediate in the reaction catalyzed by type II dehydroquinases.
Frederickson M; Roszak AW; Coggins JR; Lapthorn AJ; Abell C
Org Biomol Chem; 2004 Jun; 2(11):1592-6. PubMed ID: 15162210
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and cytotoxicity of shikimate analogues. Structure:activity studies based on 1-crotonyloxymethyl-3R,4R,5R-trihydroxycyclohex-2-enone.
Aghil O; Bibby MC; Carrington SJ; Double J; Douglas KT; Phillips RM; Shing TK
Anticancer Drug Des; 1992 Feb; 7(1):67-82. PubMed ID: 1543528
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
