66 related articles for article (PubMed ID: 14667236)
1. 2-arylureidobenzoic acids: selective noncompetitive antagonists for the homomeric kainate receptor subtype GluR5.
Valgeirsson J; Nielsen EØ; Peters D; Varming T; Mathiesen C; Kristensen AS; Madsen U
J Med Chem; 2003 Dec; 46(26):5834-43. PubMed ID: 14667236
[TBL] [Abstract][Full Text] [Related]
2. Bioisosteric modifications of 2-arylureidobenzoic acids: selective noncompetitive antagonists for the homomeric kainate receptor subtype GluR5.
Valgeirsson J; Nielsen EO; Peters D; Mathiesen C; Kristensen AS; Madsen U
J Med Chem; 2004 Dec; 47(27):6948-57. PubMed ID: 15615543
[TBL] [Abstract][Full Text] [Related]
3. Pharmacological characterization of glutamatergic agonists and antagonists at recombinant human homomeric and heteromeric kainate receptors in vitro.
Alt A; Weiss B; Ogden AM; Knauss JL; Oler J; Ho K; Large TH; Bleakman D
Neuropharmacology; 2004 May; 46(6):793-806. PubMed ID: 15033339
[TBL] [Abstract][Full Text] [Related]
4. (S)-2-Amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid, a potent and selective agonist at the GluR5 subtype of ionotropic glutamate receptors. Synthesis, modeling, and molecular pharmacology.
Brehm L; Greenwood JR; Hansen KB; Nielsen B; Egebjerg J; Stensbøl TB; Bräuner-Osborne H; Sløk FA; Kronborg TT; Krogsgaard-Larsen P
J Med Chem; 2003 Apr; 46(8):1350-8. PubMed ID: 12672235
[TBL] [Abstract][Full Text] [Related]
5. Tetrazolyl isoxazole amino acids as ionotropic glutamate receptor antagonists: synthesis, modelling and molecular pharmacology.
Frølund B; Greenwood JR; Holm MM; Egebjerg J; Madsen U; Nielsen B; Bräuner-Osborne H; Stensbøl TB; Krogsgaard-Larsen P
Bioorg Med Chem; 2005 Sep; 13(18):5391-8. PubMed ID: 16043357
[TBL] [Abstract][Full Text] [Related]
6. Synthesis of willardiine and 6-azawillardiine analogs: pharmacological characterization on cloned homomeric human AMPA and kainate receptor subtypes.
Jane DE; Hoo K; Kamboj R; Deverill M; Bleakman D; Mandelzys A
J Med Chem; 1997 Oct; 40(22):3645-50. PubMed ID: 9357531
[TBL] [Abstract][Full Text] [Related]
7. A hippocampal GluR5 kainate receptor regulating inhibitory synaptic transmission.
Clarke VR; Ballyk BA; Hoo KH; Mandelzys A; Pellizzari A; Bath CP; Thomas J; Sharpe EF; Davies CH; Ornstein PL; Schoepp DD; Kamboj RK; Collingridge GL; Lodge D; Bleakman D
Nature; 1997 Oct; 389(6651):599-603. PubMed ID: 9335499
[TBL] [Abstract][Full Text] [Related]
8. In vitro characterization of 5-carboxyl-2,4-di-benzamidobenzoic acid (NS3763), a noncompetitive antagonist of GLUK5 receptors.
Christensen JK; Varming T; Ahring PK; Jørgensen TD; Nielsen EØ
J Pharmacol Exp Ther; 2004 Jun; 309(3):1003-10. PubMed ID: 14985418
[TBL] [Abstract][Full Text] [Related]
9. Heteromeric kainate receptors formed by the coassembly of GluR5, GluR6, and GluR7.
Cui C; Mayer ML
J Neurosci; 1999 Oct; 19(19):8281-91. PubMed ID: 10493729
[TBL] [Abstract][Full Text] [Related]
10. 4-Alkylated homoibotenic acid (HIBO) analogues: versatile pharmacological agents with diverse selectivity profiles towards metabotropic and ionotropic glutamate receptor subtypes.
Madsen U; Pickering DS; Nielsen B; Bräuner-Osborne H
Neuropharmacology; 2005; 49 Suppl 1():114-9. PubMed ID: 15996690
[TBL] [Abstract][Full Text] [Related]
11. Resolution, absolute stereochemistry, and enantiopharmacology of the GluR1-4 and GluR5 antagonist 2-amino-3-[5-tert-butyl-3-(phosphonomethoxy)-4-isoxazolyl]propionic acid.
Møller EH; Egebjerg J; Brehm L; Stensbøl TB; Johansen TN; Madsen U; Krogsgaard-Larsen P
Chirality; 1999; 11(10):752-9. PubMed ID: 10561704
[TBL] [Abstract][Full Text] [Related]
12. The selective activation of the glutamate receptor GluR5 by ATPA is controlled by serine 741.
Nielsen MM; Liljefors T; Krogsgaard-Larsen P; Egebjerg J
Mol Pharmacol; 2003 Jan; 63(1):19-25. PubMed ID: 12488532
[TBL] [Abstract][Full Text] [Related]
13. 3-Substituted phenylalanines as selective AMPA- and kainate receptor ligands.
Szymańska E; Pickering DS; Nielsen B; Johansen TN
Bioorg Med Chem; 2009 Sep; 17(17):6390-401. PubMed ID: 19656686
[TBL] [Abstract][Full Text] [Related]
14. Crystal structures of the GluR5 and GluR6 ligand binding cores: molecular mechanisms underlying kainate receptor selectivity.
Mayer ML
Neuron; 2005 Feb; 45(4):539-52. PubMed ID: 15721240
[TBL] [Abstract][Full Text] [Related]
15. The methylglutamate, SYM 2081, is a potent and highly selective agonist at kainate receptors.
Donevan SD; Beg A; Gunther JM; Twyman RE
J Pharmacol Exp Ther; 1998 May; 285(2):539-45. PubMed ID: 9580595
[TBL] [Abstract][Full Text] [Related]
16. [3H]ATPA: a high affinity ligand for GluR5 kainate receptors.
Hoo K; Legutko B; Rizkalla G; Deverill M; Hawes CR; Ellis GJ; Stensbol TB; Krogsgaard-Larsen P; Skolnick P; Bleakman D
Neuropharmacology; 1999 Dec; 38(12):1811-7. PubMed ID: 10608276
[TBL] [Abstract][Full Text] [Related]
17. Kainate receptor-mediated synaptic transmission in the adult anterior cingulate cortex.
Wu LJ; Zhao MG; Toyoda H; Ko SW; Zhuo M
J Neurophysiol; 2005 Sep; 94(3):1805-13. PubMed ID: 15928066
[TBL] [Abstract][Full Text] [Related]
18. Kainate receptors exhibit differential sensitivities to (S)-5-iodowillardiine.
Swanson GT; Green T; Heinemann SF
Mol Pharmacol; 1998 May; 53(5):942-9. PubMed ID: 9584222
[TBL] [Abstract][Full Text] [Related]
19. Antiallodynic and antihyperalgesic effects of selective competitive GLUK5 (GluR5) ionotropic glutamate receptor antagonists in the capsaicin and carrageenan models in rats.
Jones CK; Alt A; Ogden AM; Bleakman D; Simmons RM; Iyengar S; Dominguez E; Ornstein PL; Shannon HE
J Pharmacol Exp Ther; 2006 Oct; 319(1):396-404. PubMed ID: 16837561
[TBL] [Abstract][Full Text] [Related]
20. The glutamate receptor GluR5 agonist (S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid and the 8-methyl analogue: synthesis, molecular pharmacology, and biostructural characterization.
Clausen RP; Naur P; Kristensen AS; Greenwood JR; Strange M; Bräuner-Osborne H; Jensen AA; Nielsen AS; Geneser U; Ringgaard LM; Nielsen B; Pickering DS; Brehm L; Gajhede M; Krogsgaard-Larsen P; Kastrup JS
J Med Chem; 2009 Aug; 52(15):4911-22. PubMed ID: 19588945
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
