467 related articles for article (PubMed ID: 14668798)
1. Stability of the Peutz-Jeghers syndrome kinase LKB1 requires its binding to the molecular chaperones Hsp90/Cdc37.
Nony P; Gaude H; Rossel M; Fournier L; Rouault JP; Billaud M
Oncogene; 2003 Dec; 22(57):9165-75. PubMed ID: 14668798
[TBL] [Abstract][Full Text] [Related]
2. Heat-shock protein 90 and Cdc37 interact with LKB1 and regulate its stability.
Boudeau J; Deak M; Lawlor MA; Morrice NA; Alessi DR
Biochem J; 2003 Mar; 370(Pt 3):849-57. PubMed ID: 12489981
[TBL] [Abstract][Full Text] [Related]
3. Cdk2: a genuine protein kinase client of Hsp90 and Cdc37.
Prince T; Sun L; Matts RL
Biochemistry; 2005 Nov; 44(46):15287-95. PubMed ID: 16285732
[TBL] [Abstract][Full Text] [Related]
4. Molecular chaperone complexes with antagonizing activities regulate stability and activity of the tumor suppressor LKB1.
Gaude H; Aznar N; Delay A; Bres A; Buchet-Poyau K; Caillat C; Vigouroux A; Rogon C; Woods A; Vanacker JM; Höhfeld J; Perret C; Meyer P; Billaud M; Forcet C
Oncogene; 2012 Mar; 31(12):1582-91. PubMed ID: 21860411
[TBL] [Abstract][Full Text] [Related]
5. Differential effects of Hsp90 inhibition on protein kinases regulating signal transduction pathways required for myoblast differentiation.
Yun BG; Matts RL
Exp Cell Res; 2005 Jul; 307(1):212-23. PubMed ID: 15922741
[TBL] [Abstract][Full Text] [Related]
6. Functional analysis of Peutz-Jeghers mutations reveals that the LKB1 C-terminal region exerts a crucial role in regulating both the AMPK pathway and the cell polarity.
Forcet C; Etienne-Manneville S; Gaude H; Fournier L; Debilly S; Salmi M; Baas A; Olschwang S; Clevers H; Billaud M
Hum Mol Genet; 2005 May; 14(10):1283-92. PubMed ID: 15800014
[TBL] [Abstract][Full Text] [Related]
7. L347P PINK1 mutant that fails to bind to Hsp90/Cdc37 chaperones is rapidly degraded in a proteasome-dependent manner.
Moriwaki Y; Kim YJ; Ido Y; Misawa H; Kawashima K; Endo S; Takahashi R
Neurosci Res; 2008 May; 61(1):43-8. PubMed ID: 18359116
[TBL] [Abstract][Full Text] [Related]
8. LKB1 interacts with and phosphorylates PTEN: a functional link between two proteins involved in cancer predisposing syndromes.
Mehenni H; Lin-Marq N; Buchet-Poyau K; Reymond A; Collart MA; Picard D; Antonarakis SE
Hum Mol Genet; 2005 Aug; 14(15):2209-19. PubMed ID: 15987703
[TBL] [Abstract][Full Text] [Related]
9. Loss of cytoplasmic retention ability of mutant LKB1 found in Peutz-Jeghers syndrome patients.
Nezu J; Oku A; Shimane M
Biochem Biophys Res Commun; 1999 Aug; 261(3):750-5. PubMed ID: 10441497
[TBL] [Abstract][Full Text] [Related]
10. Somatic mutations of LKB1 and beta-catenin genes in gastrointestinal polyps from patients with Peutz-Jeghers syndrome.
Miyaki M; Iijima T; Hosono K; Ishii R; Yasuno M; Mori T; Toi M; Hishima T; Shitara N; Tamura K; Utsunomiya J; Kobayashi N; Kuroki T; Iwama T
Cancer Res; 2000 Nov; 60(22):6311-3. PubMed ID: 11103790
[TBL] [Abstract][Full Text] [Related]
11. LKB1, a novel serine/threonine protein kinase and potential tumour suppressor, is phosphorylated by cAMP-dependent protein kinase (PKA) and prenylated in vivo.
Collins SP; Reoma JL; Gamm DM; Uhler MD
Biochem J; 2000 Feb; 345 Pt 3(Pt 3):673-80. PubMed ID: 10642527
[TBL] [Abstract][Full Text] [Related]
12. De novo germline mutation in the serine-threonine kinase STK11/LKB1 gene associated with Peutz-Jeghers syndrome.
Hernan I; Roig I; Martin B; Gamundi MJ; Martinez-Gimeno M; Carballo M
Clin Genet; 2004 Jul; 66(1):58-62. PubMed ID: 15200509
[TBL] [Abstract][Full Text] [Related]
13. Biochemical and structural studies of the interaction of Cdc37 with Hsp90.
Zhang W; Hirshberg M; McLaughlin SH; Lazar GA; Grossmann JG; Nielsen PR; Sobott F; Robinson CV; Jackson SE; Laue ED
J Mol Biol; 2004 Jul; 340(4):891-907. PubMed ID: 15223329
[TBL] [Abstract][Full Text] [Related]
14. Domain-mediated dimerization of the Hsp90 cochaperones Harc and Cdc37.
Roiniotis J; Masendycz P; Ho S; Scholz GM
Biochemistry; 2005 May; 44(17):6662-9. PubMed ID: 15850399
[TBL] [Abstract][Full Text] [Related]
15. Blocking the chaperone kinome pathway: mechanistic insights into a novel dual inhibition approach for supra-additive suppression of malignant tumors.
Grover A; Shandilya A; Agrawal V; Pratik P; Bhasme D; Bisaria VS; Sundar D
Biochem Biophys Res Commun; 2011 Jan; 404(1):498-503. PubMed ID: 21144839
[TBL] [Abstract][Full Text] [Related]
16. Somatic mutation of the Peutz-Jeghers syndrome gene, LKB1/STK11, in malignant melanoma.
Guldberg P; thor Straten P; Ahrenkiel V; Seremet T; Kirkin AF; Zeuthen J
Oncogene; 1999 Mar; 18(9):1777-80. PubMed ID: 10208439
[TBL] [Abstract][Full Text] [Related]
17. Specific association of a set of molecular chaperones including HSP90 and Cdc37 with MOK, a member of the mitogen-activated protein kinase superfamily.
Miyata Y; Ikawa Y; Shibuya M; Nishida E
J Biol Chem; 2001 Jun; 276(24):21841-8. PubMed ID: 11278794
[TBL] [Abstract][Full Text] [Related]
18. Hsp90 functions to balance the phosphorylation state of Akt during C2C12 myoblast differentiation.
Yun BG; Matts RL
Cell Signal; 2005 Dec; 17(12):1477-85. PubMed ID: 15935620
[TBL] [Abstract][Full Text] [Related]
19. Functional analysis of LKB1/STK11 mutants and two aberrant isoforms found in Peutz-Jeghers Syndrome patients.
Boudeau J; Kieloch A; Alessi DR; Stella A; Guanti G; Resta N
Hum Mutat; 2003 Feb; 21(2):172. PubMed ID: 12552571
[TBL] [Abstract][Full Text] [Related]
20. A novel germline mutation of the LKB1 gene in a patient with Peutz-Jeghers syndrome with early-onset gastric cancer.
Takahashi M; Sakayori M; Takahashi S; Kato T; Kaji M; Kawahara M; Suzuki T; Kato S; Kato S; Shibata H; Murakawa Y; Yoshioka T; Ishioka C
J Gastroenterol; 2004 Dec; 39(12):1210-4. PubMed ID: 15622488
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]