These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

167 related articles for article (PubMed ID: 14673100)

  • 1. Ligand selectivity by seeking hydrophobicity in thyroid hormone receptor.
    Borngraeber S; Budny MJ; Chiellini G; Cunha-Lima ST; Togashi M; Webb P; Baxter JD; Scanlan TS; Fletterick RJ
    Proc Natl Acad Sci U S A; 2003 Dec; 100(26):15358-63. PubMed ID: 14673100
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Hormone selectivity in thyroid hormone receptors.
    Wagner RL; Huber BR; Shiau AK; Kelly A; Cunha Lima ST; Scanlan TS; Apriletti JW; Baxter JD; West BL; Fletterick RJ
    Mol Endocrinol; 2001 Mar; 15(3):398-410. PubMed ID: 11222741
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Conformational adaptation of nuclear receptor ligand binding domains to agonists: potential for novel approaches to ligand design.
    Togashi M; Borngraeber S; Sandler B; Fletterick RJ; Webb P; Baxter JD
    J Steroid Biochem Mol Biol; 2005 Feb; 93(2-5):127-37. PubMed ID: 15860255
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Only subtle protein conformational adaptations are required for ligand binding to thyroid hormone receptors: simulations using a novel multipoint steered molecular dynamics approach.
    Martínez L; Polikarpov I; Skaf MS
    J Phys Chem B; 2008 Aug; 112(34):10741-51. PubMed ID: 18681473
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A structural role for hormone in the thyroid hormone receptor.
    Wagner RL; Apriletti JW; McGrath ME; West BL; Baxter JD; Fletterick RJ
    Nature; 1995 Dec; 378(6558):690-7. PubMed ID: 7501015
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Two resistance to thyroid hormone mutants with impaired hormone binding.
    Huber BR; Sandler B; West BL; Cunha Lima ST; Nguyen HT; Apriletti JW; Baxter JD; Fletterick RJ
    Mol Endocrinol; 2003 Apr; 17(4):643-52. PubMed ID: 12554782
    [TBL] [Abstract][Full Text] [Related]  

  • 7. X-ray crystallographic and functional studies of thyroid hormone receptor.
    Ribeiro RC; Apriletti JW; Wagner RL; Feng W; Kushner PJ; Nilsson S; Scanlan TS; West BL; Fletterick RJ; Baxter JD
    J Steroid Biochem Mol Biol; 1998 Apr; 65(1-6):133-41. PubMed ID: 9699866
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Thyroid hormone receptor-beta mutations conferring hormone resistance and reduced corepressor release exhibit decreased stability in the N-terminal ligand-binding domain.
    Huber BR; Desclozeaux M; West BL; Cunha-Lima ST; Nguyen HT; Baxter JD; Ingraham HA; Fletterick RJ
    Mol Endocrinol; 2003 Jan; 17(1):107-16. PubMed ID: 12511610
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Thyroxine-thyroid hormone receptor interactions.
    Sandler B; Webb P; Apriletti JW; Huber BR; Togashi M; Cunha Lima ST; Juric S; Nilsson S; Wagner R; Fletterick RJ; Baxter JD
    J Biol Chem; 2004 Dec; 279(53):55801-8. PubMed ID: 15466465
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-based approach for the study of thyroid hormone receptor binding affinity and subtype selectivity.
    Wang FF; Yang W; Shi YH; Cheng XR; Le GW
    J Biomol Struct Dyn; 2016 Oct; 34(10):2251-67. PubMed ID: 26510472
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A high-affinity subtype-selective agonist ligand for the thyroid hormone receptor.
    Chiellini G; Apriletti JW; Yoshihara HA; Baxter JD; Ribeiro RC; Scanlan TS
    Chem Biol; 1998 Jun; 5(6):299-306. PubMed ID: 9653548
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Thyroid receptor ligands. 1. Agonist ligands selective for the thyroid receptor beta1.
    Ye L; Li YL; Mellström K; Mellin C; Bladh LG; Koehler K; Garg N; Garcia Collazo AM; Litten C; Husman B; Persson K; Ljunggren J; Grover G; Sleph PG; George R; Malm J
    J Med Chem; 2003 Apr; 46(9):1580-8. PubMed ID: 12699376
    [TBL] [Abstract][Full Text] [Related]  

  • 13. TR surfaces and conformations required to bind nuclear receptor corepressor.
    Marimuthu A; Feng W; Tagami T; Nguyen H; Jameson JL; Fletterick RJ; Baxter JD; West BL
    Mol Endocrinol; 2002 Feb; 16(2):271-86. PubMed ID: 11818500
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Crystallization and preliminary X-ray diffraction studies of isoform alpha1 of the human thyroid hormone receptor ligand-binding domain.
    Nunes FM; Aparicio R; Santos MA; Portugal RV; Dias SM; Neves FA; Simeoni LA; Baxter JD; Webb P; Polikarpov I
    Acta Crystallogr D Biol Crystallogr; 2004 Oct; 60(Pt 10):1867-70. PubMed ID: 15388935
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of a new hormone-binding site on the surface of thyroid hormone receptor.
    Souza PC; Puhl AC; Martínez L; Aparício R; Nascimento AS; Figueira AC; Nguyen P; Webb P; Skaf MS; Polikarpov I
    Mol Endocrinol; 2014 Apr; 28(4):534-45. PubMed ID: 24552590
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms.
    Bleicher L; Aparicio R; Nunes FM; Martinez L; Gomes Dias SM; Figueira AC; Santos MA; Venturelli WH; da Silva R; Donate PM; Neves FA; Simeoni LA; Baxter JD; Webb P; Skaf MS; Polikarpov I
    BMC Struct Biol; 2008 Jan; 8():8. PubMed ID: 18237438
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular dynamics simulations reveal multiple pathways of ligand dissociation from thyroid hormone receptors.
    Martínez L; Sonoda MT; Webb P; Baxter JD; Skaf MS; Polikarpov I
    Biophys J; 2005 Sep; 89(3):2011-23. PubMed ID: 15980170
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Helix 12 dynamics and thyroid hormone receptor activity: experimental and molecular dynamics studies of Ile280 mutants.
    Souza PC; Barra GB; Velasco LF; Ribeiro IC; Simeoni LA; Togashi M; Webb P; Neves FA; Skaf MS; Martínez L; Polikarpov I
    J Mol Biol; 2011 Oct; 412(5):882-93. PubMed ID: 21530542
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Thyroid receptor ligands. Part 2: Thyromimetics with improved selectivity for the thyroid hormone receptor beta.
    Hangeland JJ; Doweyko AM; Dejneka T; Friends TJ; Devasthale P; Mellström K; Sandberg J; Grynfarb M; Sack JS; Einspahr H; Färnegårdh M; Husman B; Ljunggren J; Koehler K; Sheppard C; Malm J; Ryono DE
    Bioorg Med Chem Lett; 2004 Jul; 14(13):3549-53. PubMed ID: 15177471
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Different configurations of specific thyroid hormone response elements mediate opposite effects of thyroid hormone and GC-1 on gene expression.
    Gloss B; Giannocco G; Swanson EA; Moriscot AS; Chiellini G; Scanlan T; Baxter JD; Dillmann WH
    Endocrinology; 2005 Nov; 146(11):4926-33. PubMed ID: 16081636
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.