BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

472 related articles for article (PubMed ID: 14673996)

  • 1. Gene deletion of either interleukin-1beta, interleukin-1beta-converting enzyme, inducible nitric oxide synthase, or stromelysin 1 accelerates the development of knee osteoarthritis in mice after surgical transection of the medial collateral ligament and partial medial meniscectomy.
    Clements KM; Price JS; Chambers MG; Visco DM; Poole AR; Mason RM
    Arthritis Rheum; 2003 Dec; 48(12):3452-63. PubMed ID: 14673996
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Matrix metalloproteinases and aggrecanases cleave aggrecan in different zones of normal cartilage but colocalize in the development of osteoarthritic lesions in STR/ort mice.
    Chambers MG; Cox L; Chong L; Suri N; Cover P; Bayliss MT; Mason RM
    Arthritis Rheum; 2001 Jun; 44(6):1455-65. PubMed ID: 11407708
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cleavage of aggrecan at the Asn341-Phe342 site coincides with the initiation of collagen damage in murine antigen-induced arthritis: a pivotal role for stromelysin 1 in matrix metalloproteinase activity.
    van Meurs J; van Lent P; Stoop R; Holthuysen A; Singer I; Bayne E; Mudgett J; Poole R; Billinghurst C; van der Kraan P; Buma P; van den Berg W
    Arthritis Rheum; 1999 Oct; 42(10):2074-84. PubMed ID: 10524678
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Chondrocyte apoptosis and regional differential expression of nitric oxide in the medial meniscus following partial meniscectomy.
    Kobayashi K; Mishima H; Hashimoto S; Goomer RS; Harwood FL; Lotz M; Moriya H; Amiel D
    J Orthop Res; 2001 Sep; 19(5):802-8. PubMed ID: 11562124
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Detection of aggrecanase- and MMP-generated catabolic neoepitopes in the rat iodoacetate model of cartilage degeneration.
    Janusz MJ; Little CB; King LE; Hookfin EB; Brown KK; Heitmeyer SA; Caterson B; Poole AR; Taiwo YO
    Osteoarthritis Cartilage; 2004 Sep; 12(9):720-8. PubMed ID: 15325638
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Aggrecan degradation in human cartilage. Evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid joints.
    Lark MW; Bayne EK; Flanagan J; Harper CF; Hoerrner LA; Hutchinson NI; Singer II; Donatelli SA; Weidner JR; Williams HR; Mumford RA; Lohmander LS
    J Clin Invest; 1997 Jul; 100(1):93-106. PubMed ID: 9202061
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Relative messenger RNA expression profiling of collagenases and aggrecanases in human articular chondrocytes in vivo and in vitro.
    Bau B; Gebhard PM; Haag J; Knorr T; Bartnik E; Aigner T
    Arthritis Rheum; 2002 Oct; 46(10):2648-57. PubMed ID: 12384923
    [TBL] [Abstract][Full Text] [Related]  

  • 8. An aggrecanase and osteoarthritis.
    Karsenty G
    N Engl J Med; 2005 Aug; 353(5):522-3. PubMed ID: 16079379
    [No Abstract]   [Full Text] [Related]  

  • 9. Contribution of runt-related transcription factor 2 to the pathogenesis of osteoarthritis in mice after induction of knee joint instability.
    Kamekura S; Kawasaki Y; Hoshi K; Shimoaka T; Chikuda H; Maruyama Z; Komori T; Sato S; Takeda S; Karsenty G; Nakamura K; Chung UI; Kawaguchi H
    Arthritis Rheum; 2006 Aug; 54(8):2462-70. PubMed ID: 16868966
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Osteoprotegerin inhibits cartilage degradation through an effect on trabecular bone in murine experimental osteoarthritis.
    Kadri A; Ea HK; Bazille C; Hannouche D; Lioté F; Cohen-Solal ME
    Arthritis Rheum; 2008 Aug; 58(8):2379-86. PubMed ID: 18668550
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The pathobiology of focal lesion development in aging human articular cartilage and molecular matrix changes characteristic of osteoarthritis.
    Squires GR; Okouneff S; Ionescu M; Poole AR
    Arthritis Rheum; 2003 May; 48(5):1261-70. PubMed ID: 12746899
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The in situ up-regulation of chondrocyte interleukin-1-converting enzyme and interleukin-18 levels in experimental osteoarthritis is mediated by nitric oxide.
    Boileau C; Martel-Pelletier J; Moldovan F; Jouzeau JY; Netter P; Manning PT; Pelletier JP
    Arthritis Rheum; 2002 Oct; 46(10):2637-47. PubMed ID: 12384922
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Expression of collagen and aggrecan genes in normal and osteoarthritic murine knee joints.
    Chambers MG; Kuffner T; Cowan SK; Cheah KS; Mason RM
    Osteoarthritis Cartilage; 2002 Jan; 10(1):51-61. PubMed ID: 11795983
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Aggrecanase versus matrix metalloproteinases in the catabolism of the interglobular domain of aggrecan in vitro.
    Little CB; Flannery CR; Hughes CE; Mort JS; Roughley PJ; Dent C; Caterson B
    Biochem J; 1999 Nov; 344 Pt 1(Pt 1):61-8. PubMed ID: 10548534
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Selective inhibition of inducible nitric oxide synthase in experimental osteoarthritis is associated with reduction in tissue levels of catabolic factors.
    Pelletier JP; Lascau-Coman V; Jovanovic D; Fernandes JC; Manning P; Connor JR; Currie MG; Martel-Pelletier J
    J Rheumatol; 1999 Sep; 26(9):2002-14. PubMed ID: 10493683
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Role of aggrecanase and MMP in cartilage degradation].
    Ishiguro N; Kojima T
    Clin Calcium; 2004 Jul; 14(7):38-44. PubMed ID: 15577074
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization of and osteoarthritis susceptibility in ADAMTS-4-knockout mice.
    Glasson SS; Askew R; Sheppard B; Carito BA; Blanchet T; Ma HL; Flannery CR; Kanki K; Wang E; Peluso D; Yang Z; Majumdar MK; Morris EA
    Arthritis Rheum; 2004 Aug; 50(8):2547-58. PubMed ID: 15334469
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Early and stable upregulation of collagen type II, collagen type I and YKL40 expression levels in cartilage during early experimental osteoarthritis occurs independent of joint location and histological grading.
    Lorenz H; Wenz W; Ivancic M; Steck E; Richter W
    Arthritis Res Ther; 2005; 7(1):R156-65. PubMed ID: 15642136
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Expression of Sox9 and type IIA procollagen during attempted repair of articular cartilage damage in a transgenic mouse model of osteoarthritis.
    Salminen H; Vuorio E; Säämänen AM
    Arthritis Rheum; 2001 Apr; 44(4):947-55. PubMed ID: 11315934
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of ADAM-TS4 and ADAM-TS5 prevents aggrecan degradation in osteoarthritic cartilage.
    Malfait AM; Liu RQ; Ijiri K; Komiya S; Tortorella MD
    J Biol Chem; 2002 Jun; 277(25):22201-8. PubMed ID: 11956193
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.