BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 14676209)

  • 1. Transforming growth factor-beta1-dependent urokinase up-regulation and promotion of invasion are involved in Src-MAPK-dependent signaling in human ovarian cancer cells.
    Tanaka Y; Kobayashi H; Suzuki M; Kanayama N; Terao T
    J Biol Chem; 2004 Mar; 279(10):8567-76. PubMed ID: 14676209
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Transforming growth factor-beta1-dependent activation of Smad2/3 and up-regulation of PAI-1 expression is negatively regulated by Src in SKOV-3 human ovarian cancer cells.
    Wakahara K; Kobayashi H; Yagyu T; Matsuzaki H; Kondo T; Kurita N; Sekino H; Inagaki K; Suzuki M; Kanayama N; Terao T
    J Cell Biochem; 2004 Oct; 93(3):437-53. PubMed ID: 15372629
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Suppression of urokinase expression and invasion by a soybean Kunitz trypsin inhibitor are mediated through inhibition of Src-dependent signaling pathways.
    Inagaki K; Kobayashi H; Yoshida R; Kanada Y; Fukuda Y; Yagyu T; Kondo T; Kurita N; Kitanaka T; Yamada Y; Sakamoto Y; Suzuki M; Kanayama N; Terao T
    J Biol Chem; 2005 Sep; 280(36):31428-37. PubMed ID: 16002410
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Genetic down-regulation of phosphoinositide 3-kinase by bikunin correlates with suppression of invasion and metastasis in human ovarian cancer HRA cells.
    Kobayashi H; Suzuki M; Kanayama N; Terao T
    J Biol Chem; 2004 Feb; 279(8):6371-9. PubMed ID: 14597629
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Transforming growth factor-beta1 produced by ovarian cancer cell line HRA stimulates attachment and invasion through an up-regulation of plasminogen activator inhibitor type-1 in human peritoneal mesothelial cells.
    Hirashima Y; Kobayashi H; Suzuki M; Tanaka Y; Kanayama N; Terao T
    J Biol Chem; 2003 Jul; 278(29):26793-802. PubMed ID: 12743121
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A Kunitz-type protease inhibitor, bikunin, inhibits ovarian cancer cell invasion by blocking the calcium-dependent transforming growth factor-beta 1 signaling cascade.
    Kobayashi H; Suzuki M; Tanaka Y; Kanayama N; Terao T
    J Biol Chem; 2003 Mar; 278(10):7790-9. PubMed ID: 12496270
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Osteopontin induces AP-1-mediated secretion of urokinase-type plasminogen activator through c-Src-dependent epidermal growth factor receptor transactivation in breast cancer cells.
    Das R; Mahabeleshwar GH; Kundu GC
    J Biol Chem; 2004 Mar; 279(12):11051-64. PubMed ID: 14704150
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A soybean Kunitz trypsin inhibitor suppresses ovarian cancer cell invasion by blocking urokinase upregulation.
    Kobayashi H; Suzuki M; Kanayama N; Terao T
    Clin Exp Metastasis; 2004; 21(2):159-66. PubMed ID: 15168733
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Lysophosphatidic acid induction of urokinase plasminogen activator secretion requires activation of the p38MAPK pathway.
    Estrella VC; Eder AM; Liu S; Pustilnik TB; Tabassam FH; Claret FX; Gallick GE; Mills GB; Wiener JR
    Int J Oncol; 2007 Aug; 31(2):441-9. PubMed ID: 17611702
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Urokinase-induced smooth muscle cell responses require distinct signaling pathways: a role for the epidermal growth factor receptor.
    Nicholl SM; Roztocil E; Davies MG
    J Vasc Surg; 2005 Apr; 41(4):672-81. PubMed ID: 15874933
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transforming growth factor-beta1 induces tissue inhibitor of metalloproteinase-1 expression via activation of extracellular signal-regulated kinase and Sp1 in human fibrosarcoma cells.
    Kwak HJ; Park MJ; Cho H; Park CM; Moon SI; Lee HC; Park IC; Kim MS; Rhee CH; Hong SI
    Mol Cancer Res; 2006 Mar; 4(3):209-20. PubMed ID: 16547158
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Plasminogen activator inhibitor type-1 gene expression and induced migration in TGF-beta1-stimulated smooth muscle cells is pp60(c-src)/MEK-dependent.
    Samarakoon R; Higgins CE; Higgins SP; Kutz SM; Higgins PJ
    J Cell Physiol; 2005 Jul; 204(1):236-46. PubMed ID: 15622520
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The Src family kinase inhibitors PP2 and PP1 block TGF-beta1-mediated cellular responses by direct and differential inhibition of type I and type II TGF-beta receptors.
    Ungefroren H; Sebens S; Groth S; Gieseler F; Fändrich F
    Curr Cancer Drug Targets; 2011 May; 11(4):524-35. PubMed ID: 21395548
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Genetic downregulation of pregnancy-associated plasma protein-A (PAPP-A) by bikunin reduces IGF-I-dependent Akt and ERK1/2 activation and subsequently reduces ovarian cancer cell growth, invasion and metastasis.
    Tanaka Y; Kobayashi H; Suzuki M; Hirashima Y; Kanayama N; Terao T
    Int J Cancer; 2004 Apr; 109(3):336-47. PubMed ID: 14961570
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Thrombospondin-1 and transforming growth factor beta-1 upregulate plasminogen activator inhibitor type 1 in pancreatic cancer.
    Albo D; Berger DH; Vogel J; Tuszynski GP
    J Gastrointest Surg; 1999; 3(4):411-7. PubMed ID: 10482694
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Src phosphorylates Tyr284 in TGF-beta type II receptor and regulates TGF-beta stimulation of p38 MAPK during breast cancer cell proliferation and invasion.
    Galliher AJ; Schiemann WP
    Cancer Res; 2007 Apr; 67(8):3752-8. PubMed ID: 17440088
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Phosphatidylinositol 3-kinase/Akt regulates the balance between plasminogen activator inhibitor-1 and urokinase to promote migration of SKOV-3 ovarian cancer cells.
    Whitley BR; Beaulieu LM; Carter JC; Church FC
    Gynecol Oncol; 2007 Feb; 104(2):470-9. PubMed ID: 17070899
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Neuroprotection by transforming growth factor-beta1 involves activation of nuclear factor-kappaB through phosphatidylinositol-3-OH kinase/Akt and mitogen-activated protein kinase-extracellular-signal regulated kinase1,2 signaling pathways.
    Zhu Y; Culmsee C; Klumpp S; Krieglstein J
    Neuroscience; 2004; 123(4):897-906. PubMed ID: 14751283
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differential regulation of membrane type 1-matrix metalloproteinase activity by ERK 1/2- and p38 MAPK-modulated tissue inhibitor of metalloproteinases 2 expression controls transforming growth factor-beta1-induced pericellular collagenolysis.
    Munshi HG; Wu YI; Mukhopadhyay S; Ottaviano AJ; Sassano A; Koblinski JE; Platanias LC; Stack MS
    J Biol Chem; 2004 Sep; 279(37):39042-50. PubMed ID: 15247230
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of tumor invasion by genomic down-regulation of matriptase through suppression of activation of receptor-bound pro-urokinase.
    Suzuki M; Kobayashi H; Kanayama N; Saga Y; Suzuki M; Lin CY; Dickson RB; Terao T
    J Biol Chem; 2004 Apr; 279(15):14899-908. PubMed ID: 14747469
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.