269 related articles for article (PubMed ID: 14677632)
1. Real-time imaging of transcriptional activation in live cells reveals rapid up-regulation of the cyclin-dependent kinase inhibitor gene CDKN1A in replicative cellular senescence.
Herbig U; Wei W; Dutriaux A; Jobling WA; Sedivy JM
Aging Cell; 2003 Dec; 2(6):295-304. PubMed ID: 14677632
[TBL] [Abstract][Full Text] [Related]
2. Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a).
Herbig U; Jobling WA; Chen BP; Chen DJ; Sedivy JM
Mol Cell; 2004 May; 14(4):501-13. PubMed ID: 15149599
[TBL] [Abstract][Full Text] [Related]
3. [Cyclin dependent kinase inhibitors and replicative senescence].
Gerland LM; Ffrench M; Magaud JP
Pathol Biol (Paris); 2001 Dec; 49(10):830-9. PubMed ID: 11776695
[TBL] [Abstract][Full Text] [Related]
4. Telomere-based proliferative lifespan barriers in Werner-syndrome fibroblasts involve both p53-dependent and p53-independent mechanisms.
Davis T; Singhrao SK; Wyllie FS; Haughton MF; Smith PJ; Wiltshire M; Wynford-Thomas D; Jones CJ; Faragher RG; Kipling D
J Cell Sci; 2003 Apr; 116(Pt 7):1349-57. PubMed ID: 12615976
[TBL] [Abstract][Full Text] [Related]
5. Transcriptional activation of p21(WAF¹/CIP¹) is mediated by increased DNA binding activity and increased interaction between p53 and Sp1 via phosphorylation during replicative senescence of human embryonic fibroblasts.
Kim HS; Heo JI; Park SH; Shin JY; Kang HJ; Kim MJ; Kim SC; Kim J; Park JB; Lee JY
Mol Biol Rep; 2014; 41(4):2397-408. PubMed ID: 24445528
[TBL] [Abstract][Full Text] [Related]
6. Single-cell analysis of p16(INK4a) and p21(WAF1) expression suggests distinct mechanisms of senescence in normal human and Li-Fraumeni Syndrome fibroblasts.
Mirzayans R; Andrais B; Scott A; Paterson MC; Murray D
J Cell Physiol; 2010 Apr; 223(1):57-67. PubMed ID: 20039273
[TBL] [Abstract][Full Text] [Related]
7. Replicative senescence as a barrier to human cancer.
Parkinson EK; Munro J; Steeghs K; Morrison V; Ireland H; Forsyth N; Fitzsimmons S; Bryce S
Biochem Soc Trans; 2000 Feb; 28(2):226-33. PubMed ID: 10816133
[TBL] [Abstract][Full Text] [Related]
8. Interferon-gamma induces cellular senescence through p53-dependent DNA damage signaling in human endothelial cells.
Kim KS; Kang KW; Seu YB; Baek SH; Kim JR
Mech Ageing Dev; 2009 Mar; 130(3):179-88. PubMed ID: 19071156
[TBL] [Abstract][Full Text] [Related]
9. Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence.
Kortlever RM; Higgins PJ; Bernards R
Nat Cell Biol; 2006 Aug; 8(8):877-84. PubMed ID: 16862142
[TBL] [Abstract][Full Text] [Related]
10. Long-term growth arrest of PUVA-treated fibroblasts in G2/M in the absence of p16(INK4a) p21(CIP1) or p53.
Ma W; Hommel C; Brenneisen P; Peters T; Smit N; Sedivy J; Scharffetter-Kochanek K; Wlaschek M
Exp Dermatol; 2003 Oct; 12(5):629-37. PubMed ID: 14705804
[TBL] [Abstract][Full Text] [Related]
11. Hepatitis B virus-X protein upregulates the expression of p21waf1/cip1 and prolongs G1-->S transition via a p53-independent pathway in human hepatoma cells.
Park US; Park SK; Lee YI; Park JG; Lee YI
Oncogene; 2000 Jul; 19(30):3384-94. PubMed ID: 10918595
[TBL] [Abstract][Full Text] [Related]
12. The PPARγ-SETD8 axis constitutes an epigenetic, p53-independent checkpoint on p21-mediated cellular senescence.
Shih CT; Chang YF; Chen YT; Ma CP; Chen HW; Yang CC; Lu JC; Tsai YS; Chen HC; Tan BC
Aging Cell; 2017 Aug; 16(4):797-813. PubMed ID: 28514051
[TBL] [Abstract][Full Text] [Related]
13. p21Waf1/Cip1/Sdi1 induces permanent growth arrest with markers of replicative senescence in human tumor cells lacking functional p53.
Fang L; Igarashi M; Leung J; Sugrue MM; Lee SW; Aaronson SA
Oncogene; 1999 May; 18(18):2789-97. PubMed ID: 10362249
[TBL] [Abstract][Full Text] [Related]
14. Replicative senescence revisited.
Marcotte R; Wang E
J Gerontol A Biol Sci Med Sci; 2002 Jul; 57(7):B257-69. PubMed ID: 12084796
[TBL] [Abstract][Full Text] [Related]
15. The molecular scaffold kinase suppressor of Ras 1 is a modifier of RasV12-induced and replicative senescence.
Kortum RL; Johnson HJ; Costanzo DL; Volle DJ; Razidlo GL; Fusello AM; Shaw AS; Lewis RE
Mol Cell Biol; 2006 Mar; 26(6):2202-14. PubMed ID: 16507997
[TBL] [Abstract][Full Text] [Related]
16. ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase.
Vaziri H; West MD; Allsopp RC; Davison TS; Wu YS; Arrowsmith CH; Poirier GG; Benchimol S
EMBO J; 1997 Oct; 16(19):6018-33. PubMed ID: 9312059
[TBL] [Abstract][Full Text] [Related]
17. UCN-01-induced cell cycle arrest requires the transcriptional induction of p21(waf1/cip1) by activation of mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase pathway.
Facchinetti MM; De Siervi A; Toskos D; Senderowicz AM
Cancer Res; 2004 May; 64(10):3629-37. PubMed ID: 15150122
[TBL] [Abstract][Full Text] [Related]
18. Cdk4 disruption renders primary mouse cells resistant to oncogenic transformation, leading to Arf/p53-independent senescence.
Zou X; Ray D; Aziyu A; Christov K; Boiko AD; Gudkov AV; Kiyokawa H
Genes Dev; 2002 Nov; 16(22):2923-34. PubMed ID: 12435633
[TBL] [Abstract][Full Text] [Related]
19. Role of p14(ARF) in replicative and induced senescence of human fibroblasts.
Wei W; Hemmer RM; Sedivy JM
Mol Cell Biol; 2001 Oct; 21(20):6748-57. PubMed ID: 11564860
[TBL] [Abstract][Full Text] [Related]
20. Radiation-induced senescence-like growth arrest requires TP53 function but not telomere shortening.
Suzuki K; Mori I; Nakayama Y; Miyakoda M; Kodama S; Watanabe M
Radiat Res; 2001 Jan; 155(1 Pt 2):248-253. PubMed ID: 11121242
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]