These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

143 related articles for article (PubMed ID: 14679120)

  • 1. Lack of correlation between immunohistochemical expression of E2F-1, thymidylate synthase expression and clinical response to 5-fluorouracil in advanced colorectal cancer.
    Belvedere O; Puglisi F; Di Loreto C; Cataldi P; Guglielmi A; Aschele C; Sobrero A
    Ann Oncol; 2004 Jan; 15(1):55-8. PubMed ID: 14679120
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dihydropyrimidine dehydrogenase but not thymidylate synthase expression is associated with resistance to 5-fluorouracil in colorectal cancer.
    Nita ME; Tominaga O; Nagawa H; Tsuruo T; Muto T
    Hepatogastroenterology; 1998; 45(24):2117-22. PubMed ID: 9951876
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of retinoblastoma protein and E2F-1 transcription factor in the acquisition of 5-fluorouracil resistance by colon cancer cells.
    Obama K; Kanai M; Kawai Y; Fukushima M; Takabayashi A
    Int J Oncol; 2002 Aug; 21(2):309-14. PubMed ID: 12118326
    [TBL] [Abstract][Full Text] [Related]  

  • 4. [The correlation between thymidylate synthase expression and cytotoxicity of 5-fluorouracil in human cancer cell lines: study using polyclonal antibody against recombinant human thymidylate synthase].
    Okabe H; Tsujimoto H; Fukushima M
    Gan To Kagaku Ryoho; 1997 Apr; 24(6):705-12. PubMed ID: 9126308
    [TBL] [Abstract][Full Text] [Related]  

  • 5. UCN-01 suppresses thymidylate synthase gene expression and enhances 5-fluorouracil-induced apoptosis in a sequence-dependent manner.
    Hsueh CT; Kelsen D; Schwartz GK
    Clin Cancer Res; 1998 Sep; 4(9):2201-6. PubMed ID: 9748140
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel aspects of resistance to drugs targeted to dihydrofolate reductase and thymidylate synthase.
    Banerjee D; Mayer-Kuckuk P; Capiaux G; Budak-Alpdogan T; Gorlick R; Bertino JR
    Biochim Biophys Acta; 2002 Jul; 1587(2-3):164-73. PubMed ID: 12084458
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dynamic modulation of thymidylate synthase gene expression and fluorouracil sensitivity in human colorectal cancer cells.
    Wakasa K; Kawabata R; Nakao S; Hattori H; Taguchi K; Uchida J; Yamanaka T; Maehara Y; Fukushima M; Oda S
    PLoS One; 2015; 10(4):e0123076. PubMed ID: 25881233
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Real-time RT-PCR (TaqMan) of tumor mRNA to predict sensitivity of specimens to 5-fluorouracil.
    Kubota T
    Methods Mol Med; 2005; 111():257-65. PubMed ID: 15911984
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Overexpression of thymidylate synthase mediates desensitization for 5-fluorouracil of tumor cells.
    Saga Y; Suzuki M; Mizukami H; Kohno T; Takei Y; Fukushima M; Ozawa K
    Int J Cancer; 2003 Sep; 106(3):324-6. PubMed ID: 12845668
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Thymidylate synthase gene and protein expression correlate and are associated with response to 5-fluorouracil in human colorectal and gastric tumors.
    Johnston PG; Lenz HJ; Leichman CG; Danenberg KD; Allegra CJ; Danenberg PV; Leichman L
    Cancer Res; 1995 Apr; 55(7):1407-12. PubMed ID: 7882343
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Predictive role of thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase expression in colorectal cancer patients receiving adjuvant 5-fluorouracil.
    Ciaparrone M; Quirino M; Schinzari G; Zannoni G; Corsi DC; Vecchio FM; Cassano A; La Torre G; Barone C
    Oncology; 2006; 70(5):366-77. PubMed ID: 17179731
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Thymidylate synthase protein expression in primary colorectal cancer: lack of correlation with outcome and response to fluorouracil in metastatic disease sites.
    Johnston PG; Benson AB; Catalano P; Rao MS; O'Dwyer PJ; Allegra CJ
    J Clin Oncol; 2003 Mar; 21(5):815-9. PubMed ID: 12610179
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Intratumoural thymidylate synthase and dihydropyrimidine dehydrogenase activities are good predictors of 5-fluorouracil sensitivity in colorectal cancer.
    Ishibiki Y; Kitajima M; Sakamoto K; Tomiki Y; Sakamoto S; Kamano T
    J Int Med Res; 2003; 31(3):181-7. PubMed ID: 12870370
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Correlation of thymidylate synthase, thymidine phosphorylase and dihydropyrimidine dehydrogenase with sensitivity of gastrointestinal cancer cells to 5-fluorouracil and 5-fluoro-2'-deoxyuridine.
    Ma T; Zhu ZG; Ji YB; Zhang Y; Yu YY; Liu BY; Yin HR; Lin YZ
    World J Gastroenterol; 2004 Jan; 10(2):172-6. PubMed ID: 14716816
    [TBL] [Abstract][Full Text] [Related]  

  • 15. mRNA expression levels of E2F transcription factors correlate with dihydrofolate reductase, reduced folate carrier, and thymidylate synthase mRNA expression in osteosarcoma.
    Sowers R; Toguchida J; Qin J; Meyers PA; Healey JH; Huvos A; Banerjee D; Bertino JR; Gorlick R
    Mol Cancer Ther; 2003 Jun; 2(6):535-41. PubMed ID: 12813132
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CDK inhibitor enhances the sensitivity to 5-fluorouracil in colorectal cancer cells.
    Takagi K; Sowa Y; Cevik OM; Nakanishi R; Sakai T
    Int J Oncol; 2008 May; 32(5):1105-10. PubMed ID: 18425338
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Relationships between the expression of thymidylate synthase, dihydropyrimidine dehydrogenase, and orotate phosphoribosyltransferase and cell proliferative activity and 5-fluorouracil sensitivity in colorectal carcinoma.
    Fujii R; Seshimo A; Kameoka S
    Int J Clin Oncol; 2003 Apr; 8(2):72-8. PubMed ID: 12720098
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Thymidylate synthase and microsatellite instability in colorectal cancer: implications for disease free survival, treatment response and survival with metastases.
    Bendardaf R; Lamlum H; Ristamäki R; Korkeila E; Syrjänen K; Pyrhönen S
    Acta Oncol; 2008; 47(6):1046-53. PubMed ID: 17943475
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Single nucleotide polymorphism in the 5' tandem repeat sequences of thymidylate synthase gene predicts for response to fluorouracil-based chemotherapy in advanced colorectal cancer patients.
    Marcuello E; Altés A; del Rio E; César A; Menoyo A; Baiget M
    Int J Cancer; 2004 Dec; 112(5):733-7. PubMed ID: 15386371
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Predicting 5-fluorouracil chemosensitivity of liver metastases from colorectal cancer using primary tumor specimens: three-gene expression model predicts clinical response.
    Matsuyama R; Togo S; Shimizu D; Momiyama N; Ishikawa T; Ichikawa Y; Endo I; Kunisaki C; Suzuki H; Hayasizaki Y; Shimada H
    Int J Cancer; 2006 Jul; 119(2):406-13. PubMed ID: 16477629
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.