These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
4. Chemical complementation: a definitive phenotypic strategy for identifying small molecule inhibitors of elusive cellular targets. Vogt A; Lazo JS Pharmacol Ther; 2005 Aug; 107(2):212-21. PubMed ID: 15925410 [TBL] [Abstract][Full Text] [Related]
5. Use of multicomponent, domino, and other one-pot syntheses on solid phase: powerful tools for the generation of libraries of diverse and complex compounds. Pulici M; Cervi G; Martina K; Quartieri F Comb Chem High Throughput Screen; 2003 Nov; 6(7):693-727. PubMed ID: 14683495 [TBL] [Abstract][Full Text] [Related]
6. Forward chemical genetics: progress and obstacles on the path to a new pharmacopoeia. Lokey RS Curr Opin Chem Biol; 2003 Feb; 7(1):91-6. PubMed ID: 12547432 [TBL] [Abstract][Full Text] [Related]
7. Discovery and use of small molecules for probing biological processes in zebrafish. Peterson RT; Fishman MC Methods Cell Biol; 2004; 76():569-91. PubMed ID: 15602893 [No Abstract] [Full Text] [Related]
8. Forecasting roles of combinatorial chemistry in the age of genomically derived drug discovery targets. Thorpe DS Comb Chem High Throughput Screen; 2000 Oct; 3(5):421-36. PubMed ID: 11032958 [TBL] [Abstract][Full Text] [Related]
9. Target-oriented and diversity-oriented organic synthesis in drug discovery. Schreiber SL Science; 2000 Mar; 287(5460):1964-9. PubMed ID: 10720315 [TBL] [Abstract][Full Text] [Related]
10. Combinatorial chemistry as a tool for drug discovery. Floyd CD; Leblanc C; Whittaker M Prog Med Chem; 1999; 36():91-168. PubMed ID: 10818672 [TBL] [Abstract][Full Text] [Related]
11. State-of-the-art genomics approaches in toxicology. Van Hummelen P; Sasaki J Mutat Res; 2010 Dec; 705(3):165-71. PubMed ID: 20466069 [TBL] [Abstract][Full Text] [Related]
12. Establishment of the platform for reverse chemical genetics targeting novel protein-protein interactions. Koga H Mol Biosyst; 2006 Mar; 2(3-4):159-64. PubMed ID: 16880933 [TBL] [Abstract][Full Text] [Related]
13. Key aspects of the Novartis compound collection enhancement project for the compilation of a comprehensive chemogenomics drug discovery screening collection. Jacoby E; Schuffenhauer A; Popov M; Azzaoui K; Havill B; Schopfer U; Engeloch C; Stanek J; Acklin P; Rigollier P; Stoll F; Koch G; Meier P; Orain D; Giger R; Hinrichs J; Malagu K; Zimmermann J; Roth HJ Curr Top Med Chem; 2005; 5(4):397-411. PubMed ID: 15892682 [TBL] [Abstract][Full Text] [Related]
15. Chemical genomics as an emerging paradigm for postgenomic drug discovery. Salemme FR Pharmacogenomics; 2003 May; 4(3):257-67. PubMed ID: 12718717 [TBL] [Abstract][Full Text] [Related]
16. Natural product-like and other biologically active heterocyclic libraries using solid-phase techniques in the post-genomic era. Knepper K; Gil C; Bräse S Comb Chem High Throughput Screen; 2003 Nov; 6(7):673-91. PubMed ID: 14683494 [TBL] [Abstract][Full Text] [Related]
17. Chemical genetics: an evolving toolbox for target identification and lead optimization. Boshoff HI; Dowd CS Prog Drug Res; 2007; 64():49, 51-77. PubMed ID: 17195471 [TBL] [Abstract][Full Text] [Related]
18. [Applications of chemical genetics in biomedical research]. Jing Q; Zhao J; Zhao B; Zhang S; Miao J Sheng Wu Yi Xue Gong Cheng Xue Za Zhi; 2009 Apr; 26(2):448-51. PubMed ID: 19499823 [TBL] [Abstract][Full Text] [Related]
19. Characterization of soluble polymer supported organic compounds by LC/electrospray ionization MS toward a complete automation of the liquid-phase process in combinatorial chemistry. Enjalbal C; Lamaty F; Sanchez P; Suberchicot E; Ribière P; Varray S; Lazaro R; Yadav-Bhatnagar N; Martinez J; Aubagna JL Anal Chem; 2003 Jan; 75(2):175-84. PubMed ID: 12553749 [TBL] [Abstract][Full Text] [Related]