BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 14684318)

  • 21. Steroid sulfatase: a pivotal player in estrogen synthesis and metabolism.
    Purohit A; Woo LW; Potter BV
    Mol Cell Endocrinol; 2011 Jul; 340(2):154-60. PubMed ID: 21693170
    [TBL] [Abstract][Full Text] [Related]  

  • 22. 2-difluoromethyloestrone 3-O-sulphamate, a highly potent steroid sulphatase inhibitor.
    Reed JE; Woo LW; Robinson JJ; Leblond B; Leese MP; Purohit A; Reed MJ; Potter BV
    Biochem Biophys Res Commun; 2004 Apr; 317(1):169-75. PubMed ID: 15047163
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Estrone 3-sulfate mimics, inhibitors of estrone sulfatase activity: homology model construction and docking studies.
    Howarth NM; Purohit A; Robinson JJ; Vicker N; Reed MJ; Potter BV
    Biochemistry; 2002 Dec; 41(50):14801-14. PubMed ID: 12475228
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Development of novel steroid sulfatase inhibitors; II. TZS-8478 potently inhibits the growth of breast tumors in postmenopausal breast cancer model rats.
    Saito T; Kinoshita S; Fujii T; Bandoh K; Fuse S; Yamauchi Y; Koizumi N; Horiuchi T
    J Steroid Biochem Mol Biol; 2004 Feb; 88(2):167-73. PubMed ID: 15084348
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Inactivation of recombinant human steroid sulfatase by KW-2581.
    Ishida H; Sato N; Hosogi J; Tanaka H; Kuwabara T
    J Steroid Biochem Mol Biol; 2008 Jan; 108(1-2):17-22. PubMed ID: 17945483
    [TBL] [Abstract][Full Text] [Related]  

  • 26. 17Alpha-alkan (or alkyn) amide derivatives of estradiol as inhibitors of steroid-sulfatase activity.
    Boivin RP; Labrie F; Poirier D
    Steroids; 1999 Dec; 64(12):825-33. PubMed ID: 10576217
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Stimulation of MCF-7 breast cancer cell proliferation by estrone sulfate and dehydroepiandrosterone sulfate: inhibition by novel non-steroidal steroid sulfatase inhibitors.
    Billich A; Nussbaumer P; Lehr P
    J Steroid Biochem Mol Biol; 2000; 73(5):225-35. PubMed ID: 11070351
    [TBL] [Abstract][Full Text] [Related]  

  • 28. 17 alpha-alkyl- or 17 alpha-substituted benzyl-17 beta-estradiols: a new family of estrone-sulfatase inhibitors.
    Poirier D; Boivin RP
    Bioorg Med Chem Lett; 1998 Jul; 8(14):1891-6. PubMed ID: 9873454
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Design and synthesis of dansyl-labeled inhibitors of steroid sulfatase for optical imaging.
    Maltais R; Ngueta Djiemeny A; Roy J; Barbeau X; Lambert JP; Poirier D
    Bioorg Med Chem; 2020 Apr; 28(7):115368. PubMed ID: 32122754
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Solid-phase parallel synthesis of 17alpha-substituted estradiol sulfamate and phenol libraries using the multidetachable sulfamate linker.
    Ciobanu LC; Poirier D
    J Comb Chem; 2003; 5(4):429-40. PubMed ID: 12857111
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Phase I study of STX 64 (667 Coumate) in breast cancer patients: the first study of a steroid sulfatase inhibitor.
    Stanway SJ; Purohit A; Woo LW; Sufi S; Vigushin D; Ward R; Wilson RH; Stanczyk FZ; Dobbs N; Kulinskaya E; Elliott M; Potter BV; Reed MJ; Coombes RC
    Clin Cancer Res; 2006 Mar; 12(5):1585-92. PubMed ID: 16533785
    [TBL] [Abstract][Full Text] [Related]  

  • 32. A novel dual-target steroid sulfatase inhibitor and antiestrogen: SR 16157, a promising agent for the therapy of breast cancer.
    Rasmussen LM; Zaveri NT; Stenvang J; Peters RH; Lykkesfeldt AE
    Breast Cancer Res Treat; 2007 Dec; 106(2):191-203. PubMed ID: 17268816
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Steroid sulfatase inhibitors: promising new tools for breast cancer therapy?
    Geisler J; Sasano H; Chen S; Purohit A
    J Steroid Biochem Mol Biol; 2011 May; 125(1-2):39-45. PubMed ID: 21356310
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Synthesis and Biological Evaluation of Fluorinated 3-Phenylcoumarin-7-O-Sulfamate Derivatives as Steroid Sulfatase Inhibitors.
    Demkowicz S; Daśko M; Kozak W; Krawczyk K; Witt D; Masłyk M; Kubiński K; Rachon J
    Chem Biol Drug Des; 2016 Feb; 87(2):233-8. PubMed ID: 26280898
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Steroid sulfatase inhibitor alters blood pressure and steroid profiles in hypertensive rats.
    Valigora SD; Lib PK; Dunphy G; Turner M; Ely DL
    J Steroid Biochem Mol Biol; 2000 Jun; 73(3-4):113-22. PubMed ID: 10925210
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Design and synthesis of silicon-containing steroid sulfatase inhibitors possessing pro-estrogen antagonistic character.
    Kajita D; Nakamura M; Matsumoto Y; Makishima M; Hashimoto Y
    Bioorg Med Chem; 2014 Apr; 22(7):2244-52. PubMed ID: 24630694
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Steroid sulfatase: a new target for the endocrine therapy of breast cancer.
    Stanway SJ; Delavault P; Purohit A; Woo LW; Thurieau C; Potter BV; Reed MJ
    Oncologist; 2007 Apr; 12(4):370-4. PubMed ID: 17470679
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Synthesis and biological activity of the superestrogen (E)-17-oximino-3-O-sulfamoyl-1,3,5(10)-estratriene: x-ray crystal structure of (E)-17-oximino-3-hydroxy-1,3,5(10)-estratriene.
    Hejaz HA; Purohit A; Mahon MF; Reed MJ; Potter BV
    J Med Chem; 1999 Aug; 42(16):3188-92. PubMed ID: 10447965
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Inactivation of steroid sulfatase by an active site-directed inhibitor, estrone-3-O-sulfamate.
    Purohit A; Williams GJ; Howarth NM; Potter BV; Reed MJ
    Biochemistry; 1995 Sep; 34(36):11508-14. PubMed ID: 7547880
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Potent inhibition of steroid sulfatase activity by 3-O-sulfamate 17alpha-benzyl(or 4'-tert-butylbenzyl)estra-1,3,5(10)-trienes: combination of two substituents at positions C3 and c17alpha of estradiol.
    Ciobanu LC; Boivin RP; Luu-The V; Labrie F; Poirier D
    J Med Chem; 1999 Jun; 42(12):2280-6. PubMed ID: 10377235
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.