BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

312 related articles for article (PubMed ID: 14684331)

  • 1. Carbonic anhydrase inhibitors: E7070, a sulfonamide anticancer agent, potently inhibits cytosolic isozymes I and II, and transmembrane, tumor-associated isozyme IX.
    Abbate F; Casini A; Owa T; Scozzafava A; Supuran CT
    Bioorg Med Chem Lett; 2004 Jan; 14(1):217-23. PubMed ID: 14684331
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Carbonic anhydrase inhibitors. Synthesis, and molecular structure of novel series N-substituted N'-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)guanidines and their inhibition of human cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII.
    Żołnowska B; Sławiński J; Pogorzelska A; Chojnacki J; Vullo D; Supuran CT
    Eur J Med Chem; 2014 Jan; 71():135-47. PubMed ID: 24291567
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Carbonic anhydrase inhibitors. Inhibition of cytosolic isozymes I and II and transmembrane, cancer-associated isozyme IX with lipophilic sulfonamides.
    Franchi M; Vullo D; Gallori E; Pastorek J; Russo A; Scozzafava A; Pastorekova S; Supuran CT
    J Enzyme Inhib Med Chem; 2003 Aug; 18(4):333-8. PubMed ID: 14567548
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Carbonic anhydrase inhibitors: novel sulfonamides incorporating 1,3,5-triazine moieties as inhibitors of the cytosolic and tumour-associated carbonic anhydrase isozymes I, II and IX.
    Garaj V; Puccetti L; Fasolis G; Winum JY; Montero JL; Scozzafava A; Vullo D; Innocenti A; Supuran CT
    Bioorg Med Chem Lett; 2005 Jun; 15(12):3102-8. PubMed ID: 15905091
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Carbonic anhydrase inhibitors. Inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, IX, and XII with Schiff's bases incorporating chromone and aromatic sulfonamide moieties, and their zinc complexes.
    Puccetti L; Fasolis G; Vullo D; Chohan ZH; Scozzafava A; Supuran CT
    Bioorg Med Chem Lett; 2005 Jun; 15(12):3096-101. PubMed ID: 15908204
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Carbonic anhydrase inhibitors. Inhibition of the cytosolic and tumor-associated carbonic anhydrase isozymes I, II, and IX with a series of 1,3,4-thiadiazole- and 1,2,4-triazole-thiols.
    Almajan GL; Innocenti A; Puccetti L; Manole G; Barbuceanu S; Saramet I; Scozzafava A; Supuran CT
    Bioorg Med Chem Lett; 2005 May; 15(9):2347-52. PubMed ID: 15837323
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating thioureido-sulfanilyl scaffolds.
    Puccetti L; Fasolis G; Cecchi A; Winum JY; Gamberi A; Montero JL; Scozzafava A; Supuran CT
    Bioorg Med Chem Lett; 2005 May; 15(9):2359-64. PubMed ID: 15837325
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Carbonic anhydrase inhibitors: synthesis and inhibition of the human cytosolic isozymes I and II and transmembrane isozymes IX, XII (cancer-associated) and XIV with 4-substituted 3-pyridinesulfonamides.
    Brzozowski Z; Sławiński J; Saczewski F; Innocenti A; Supuran CT
    Eur J Med Chem; 2010 Jun; 45(6):2396-404. PubMed ID: 20202722
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Carbonic anhydrase inhibitors: X-ray crystal structure of a benzenesulfonamide strong CA II and CA IX inhibitor bearing a pentafluorophenylaminothioureido tail in complex with isozyme II.
    Di Fiore A; De Simone G; Menchise V; Pedone C; Casini A; Scozzafava A; Supuran CT
    Bioorg Med Chem Lett; 2005 Apr; 15(7):1937-42. PubMed ID: 15780637
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, IX, and XII with N-hydroxysulfamides--a new zinc-binding function in the design of inhibitors.
    Winum JY; Innocenti A; Nasr J; Montero JL; Scozzafava A; Vullo D; Supuran CT
    Bioorg Med Chem Lett; 2005 May; 15(9):2353-8. PubMed ID: 15837324
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Carbonic anhydrase inhibitors: X-ray and molecular modeling study for the interaction of a fluorescent antitumor sulfonamide with isozyme II and IX.
    Alterio V; Vitale RM; Monti SM; Pedone C; Scozzafava A; Cecchi A; De Simone G; Supuran CT
    J Am Chem Soc; 2006 Jun; 128(25):8329-35. PubMed ID: 16787097
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 5-Substituted-(1,2,3-triazol-4-yl)thiophene-2-sulfonamides strongly inhibit human carbonic anhydrases I, II, IX and XII: solution and X-ray crystallographic studies.
    Leitans J; Sprudza A; Tanc M; Vozny I; Zalubovskis R; Tars K; Supuran CT
    Bioorg Med Chem; 2013 Sep; 21(17):5130-8. PubMed ID: 23859774
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel 2-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)-1-(1,3,5-triazin-2-ylamino)guanidine derivatives: Inhibition of human carbonic anhydrase cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII, anticancer activity, and molecular modeling studies.
    Żołnowska B; Sławiński J; Szafrański K; Angeli A; Supuran CT; Kawiak A; Wieczór M; Zielińska J; Bączek T; Bartoszewska S
    Eur J Med Chem; 2018 Jan; 143():1931-1941. PubMed ID: 29146134
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Carbonic anhydrase inhibitors: inhibition of transmembrane, tumor-associated isozyme IX, and cytosolic isozymes I and II with aliphatic sulfamates.
    Winum JY; Vullo D; Casini A; Montero JL; Scozzafava A; Supuran CT
    J Med Chem; 2003 Dec; 46(25):5471-7. PubMed ID: 14640555
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Carbonic anhydrase inhibitors. Regioselective synthesis of novel 1-substituted 1,4-dihydro-4-oxo-3-pyridinesulfonamides and their inhibition of the human cytosolic isozymes I and II and transmembrane cancer-associated isozymes IX and XII.
    Brzozowski Z; Sławiński J; Innocenti A; Supuran CT
    Eur J Med Chem; 2010 Sep; 45(9):3656-61. PubMed ID: 20554082
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Fluorescent Silica Nanoparticles with Multivalent Inhibitory Effects towards Carbonic Anhydrases.
    Touisni N; Kanfar N; Ulrich S; Dumy P; Supuran CT; Mehdi A; Winum JY
    Chemistry; 2015 Jul; 21(29):10306-9. PubMed ID: 25965260
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of 3,4-Dihydroisoquinoline-2(1H)-sulfonamides as potent carbonic anhydrase inhibitors: synthesis, biological evaluation, and enzyme--ligand X-ray studies.
    Gitto R; Agnello S; Ferro S; De Luca L; Vullo D; Brynda J; Mader P; Supuran CT; Chimirri A
    J Med Chem; 2010 Mar; 53(6):2401-8. PubMed ID: 20170095
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating 1,2,4-triazine moieties.
    Garaj V; Puccetti L; Fasolis G; Winum JY; Montero JL; Scozzafava A; Vullo D; Innocenti A; Supuran CT
    Bioorg Med Chem Lett; 2004 Nov; 14(21):5427-33. PubMed ID: 15454239
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/tumor-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides derived from 4-isothiocyanato-benzolamide.
    Cecchi A; Winum JY; Innocenti A; Vullo D; Montero JL; Scozzafava A; Supuran CT
    Bioorg Med Chem Lett; 2004 Dec; 14(23):5775-80. PubMed ID: 15501039
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Carbonic anhydrase inhibitors: inhibition of the human isozymes I, II, VA, and IX with a library of substituted difluoromethanesulfonamides.
    Cecchi A; Taylor SD; Liu Y; Hill B; Vullo D; Scozzafava A; Supuran CT
    Bioorg Med Chem Lett; 2005 Dec; 15(23):5192-6. PubMed ID: 16203142
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.