These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. A new modular polyketide synthase in the erythromycin producer Saccharopolyspora erythraea. Boakes S; Oliynyk M; Cortés J; Böhm I; Rudd BA; Revill WP; Staunton J; Leadlay PF J Mol Microbiol Biotechnol; 2004; 8(2):73-80. PubMed ID: 15925898 [TBL] [Abstract][Full Text] [Related]
4. An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea. Cortes J; Haydock SF; Roberts GA; Bevitt DJ; Leadlay PF Nature; 1990 Nov; 348(6297):176-8. PubMed ID: 2234082 [TBL] [Abstract][Full Text] [Related]
5. Glycosylation engineering of spinosyn analogues containing an L-olivose moiety. Gaisser S; Carletti I; Schell U; Graupner PR; Sparks TC; Martin CJ; Wilkinson B Org Biomol Chem; 2009 Apr; 7(8):1705-8. PubMed ID: 19343260 [TBL] [Abstract][Full Text] [Related]
6. The molecular basis of Celmer's rules: the stereochemistry of the condensation step in chain extension on the erythromycin polyketide synthase. Weissman KJ; Timoney M; Bycroft M; Grice P; Hanefeld U; Staunton J; Leadlay PF Biochemistry; 1997 Nov; 36(45):13849-55. PubMed ID: 9374862 [TBL] [Abstract][Full Text] [Related]
11. Expression and kinetic analysis of the substrate specificity of modules 5 and 6 of the picromycin/methymycin polyketide synthase. Yin Y; Lu H; Khosla C; Cane DE J Am Chem Soc; 2003 May; 125(19):5671-6. PubMed ID: 12733905 [TBL] [Abstract][Full Text] [Related]
12. Spontaneous priming of a downstream module in 6-deoxyerythronolide B synthase leads to polyketide biosynthesis. Jacobsen JR; Cane DE; Khosla C Biochemistry; 1998 Apr; 37(14):4928-34. PubMed ID: 9538011 [TBL] [Abstract][Full Text] [Related]
13. Biosynthesis of the erythromycin macrolactone and a rational approach for producing hybrid macrolides. Donadio S; Staver MJ; McAlpine JB; Swanson SJ; Katz L Gene; 1992 Jun; 115(1-2):97-103. PubMed ID: 1612455 [TBL] [Abstract][Full Text] [Related]
14. New erythromycin derivatives from Saccharopolyspora erythraea using sugar O-methyltransferases from the spinosyn biosynthetic gene cluster. Gaisser S; Lill R; Wirtz G; Grolle F; Staunton J; Leadlay PF Mol Microbiol; 2001 Sep; 41(5):1223-31. PubMed ID: 11555300 [TBL] [Abstract][Full Text] [Related]
15. Repositioning of a domain in a modular polyketide synthase to promote specific chain cleavage. Cortes J; Wiesmann KE; Roberts GA; Brown MJ; Staunton J; Leadlay PF Science; 1995 Jun; 268(5216):1487-9. PubMed ID: 7770773 [TBL] [Abstract][Full Text] [Related]
16. An unexpected interaction between the modular polyketide synthases, erythromycin DEBS1 and pikromycin PikAIV, leads to efficient triketide lactone synthesis. Kim BS; Cropp TA; Florova G; Lindsay Y; Sherman DH; Reynolds KA Biochemistry; 2002 Sep; 41(35):10827-33. PubMed ID: 12196022 [TBL] [Abstract][Full Text] [Related]
17. Heterologous expression in Escherichia coli of an intact multienzyme component of the erythromycin-producing polyketide synthase. Roberts GA; Staunton J; Leadlay PF Eur J Biochem; 1993 May; 214(1):305-11. PubMed ID: 8508800 [TBL] [Abstract][Full Text] [Related]
18. Genes for the biosynthesis of spinosyns: applications for yield improvement in Saccharopolyspora spinosa. Madduri K; Waldron C; Matsushima P; Broughton MC; Crawford K; Merlo DJ; Baltz RH J Ind Microbiol Biotechnol; 2001 Dec; 27(6):399-402. PubMed ID: 11774006 [TBL] [Abstract][Full Text] [Related]
19. Biosynthesis of complex polyketides in a metabolically engineered strain of E. coli. Pfeifer BA; Admiraal SJ; Gramajo H; Cane DE; Khosla C Science; 2001 Mar; 291(5509):1790-2. PubMed ID: 11230695 [TBL] [Abstract][Full Text] [Related]