BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

143 related articles for article (PubMed ID: 14686785)

  • 1. Overexpression of CYP2D6 attenuates the toxicity of MPP+ in actively dividing and differentiated PC12 cells.
    Matoh N; Tanaka S; Takehashi M; Banasik M; Stedeford T; Masliah E; Suzuki S; Nishimura Y; Ueda K
    Gene Expr; 2003; 11(3-4):117-24. PubMed ID: 14686785
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metabolism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by mitochondrion-targeted cytochrome P450 2D6: implications in Parkinson disease.
    Bajpai P; Sangar MC; Singh S; Tang W; Bansal S; Chowdhury G; Cheng Q; Fang JK; Martin MV; Guengerich FP; Avadhani NG
    J Biol Chem; 2013 Feb; 288(6):4436-51. PubMed ID: 23258538
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Toxic effects of MPP(+) and MPTP in PC12 cells independent of reactive oxygen species formation.
    Fonck C; Baudry M
    Brain Res; 2001 Jun; 905(1-2):199-206. PubMed ID: 11423095
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cytochrome P450 2D6 enzyme neuroprotects against 1-methyl-4-phenylpyridinium toxicity in SH-SY5Y neuronal cells.
    Mann A; Tyndale RF
    Eur J Neurosci; 2010 Apr; 31(7):1185-93. PubMed ID: 20345925
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Prostaglandin analogue misoprostol attenuates neurotoxin 1-methyl-4-phenylpyridinium-induced mitochondrial damage and cell death in differentiated PC12 cells.
    Choi EJ; Han JH; Lee CS
    Brain Res Bull; 2008 Nov; 77(5):293-300. PubMed ID: 18602972
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Econazole attenuates cytotoxicity of 1-methyl-4-phenylpyridinium by suppressing mitochondrial membrane permeability transition.
    Lee CS; Yim SB; Song JH; Han ES
    Brain Res Bull; 2006 May; 69(6):687-94. PubMed ID: 16716839
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Does thioredoxin-1 prevent mitochondria- and endoplasmic reticulum-mediated neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine?
    Bai J; Nakamura H; Kwon YW; Tanito M; Ueda S; Tanaka T; Hattori I; Ban S; Momoi T; Kitao Y; Ogawa S; Yodoi J
    Antioxid Redox Signal; 2007 May; 9(5):603-8. PubMed ID: 17465883
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cytotoxicity of 1-amino-4-phenyl-1,2,3,6-tetrahydropyridine and 1-amino-4-phenylpyridinium ion, 1-amino analogues of MPTP and MPP+, to clonal pheochromocytoma PC12 cells.
    Kohda K; Noda Y; Aoyama S; Umeda M; Sumino T; Kaiya T; Maruyama W; Naoi M
    Chem Res Toxicol; 1998 Nov; 11(11):1249-53. PubMed ID: 9815183
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Modulation of 1-methyl-4-phenylpyridinium-induced mitochondrial dysfunction and cell death in PC12 cells by K(ATP) channel block.
    Lee CS; Kim YJ; Ko HH; Han ES
    J Neural Transm (Vienna); 2007 Mar; 114(3):297-305. PubMed ID: 17109075
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The selective toxicity of 1-methyl-4-phenylpyridinium to dopaminergic neurons: the role of mitochondrial complex I and reactive oxygen species revisited.
    Nakamura K; Bindokas VP; Marks JD; Wright DA; Frim DM; Miller RJ; Kang UJ
    Mol Pharmacol; 2000 Aug; 58(2):271-8. PubMed ID: 10908294
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Protective effect of erythropoietin against 1-methyl-4-phenylpyridinium-induced neurodegenaration in PC12 cells.
    Wu Y; Shang Y; Sun SG; Liu RG; Yang WQ
    Neurosci Bull; 2007 May; 23(3):156-64. PubMed ID: 17612594
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Piperine inhibition of 1-methyl-4-phenylpyridinium-induced mitochondrial dysfunction and cell death in PC12 cells.
    Lee CS; Han ES; Kim YK
    Eur J Pharmacol; 2006 May; 537(1-3):37-44. PubMed ID: 16624279
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Protective effect of glycyrrhizin on 1-methyl-4-phenylpyridinium-induced mitochondrial damage and cell death in differentiated PC12 cells.
    Yim SB; Park SE; Lee CS
    J Pharmacol Exp Ther; 2007 May; 321(2):816-22. PubMed ID: 17314199
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Overexpression of TFAM, NRF-1 and myr-AKT protects the MPP(+)-induced mitochondrial dysfunctions in neuronal cells.
    Piao Y; Kim HG; Oh MS; Pak YK
    Biochim Biophys Acta; 2012 May; 1820(5):577-85. PubMed ID: 21856379
    [TBL] [Abstract][Full Text] [Related]  

  • 15. β-Naphthoflavone and Ethanol Reverse Mitochondrial Dysfunction in A Parkinsonian Model of Neurodegeneration.
    Fernandez-Abascal J; Chiaino E; Frosini M; Davey GP; Valoti M
    Int J Mol Sci; 2020 May; 21(11):. PubMed ID: 32486438
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Toxicity to PC12 cells of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
    McNaught KS; Thull U; Carrupt PA; Altomare C; Cellamare S; Carotti A; Testa B; Jenner P; Marsden CD
    Neurosci Lett; 1996 Mar; 206(1):37-40. PubMed ID: 8848276
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Antidepressants reveal differential effect against 1-methyl-4-phenylpyridinium toxicity in differentiated PC12 cells.
    Han YS; Lee CS
    Eur J Pharmacol; 2009 Feb; 604(1-3):36-44. PubMed ID: 19135049
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is N-demethylated by cytochromes P450 2D6, 1A2 and 3A4--implications for susceptibility to Parkinson's disease.
    Coleman T; Ellis SW; Martin IJ; Lennard MS; Tucker GT
    J Pharmacol Exp Ther; 1996 May; 277(2):685-90. PubMed ID: 8627546
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sex- and brain region-specific role of cytochrome c oxidase in 1-methyl-4-phenylpyridinium-mediated astrocyte vulnerability.
    Sundar Boyalla S; Barbara Victor M; Roemgens A; Beyer C; Arnold S
    J Neurosci Res; 2011 Dec; 89(12):2068-82. PubMed ID: 21598289
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Comparative aromatic hydroxylation and N-demethylation of MPTP neurotoxin and its analogs, N-methylated beta-carboline and isoquinoline alkaloids, by human cytochrome P450 2D6.
    Herraiz T; Guillén H; Arán VJ; Idle JR; Gonzalez FJ
    Toxicol Appl Pharmacol; 2006 Nov; 216(3):387-98. PubMed ID: 16870220
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.