BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

179 related articles for article (PubMed ID: 14690453)

  • 1. Critical cysteine residues for regulation of integrin alphaIIbbeta3 are clustered in the epidermal growth factor domains of the beta3 subunit.
    Kamata T; Ambo H; Puzon-McLaughlin W; Tieu KK; Handa M; Ikeda Y; Takada Y
    Biochem J; 2004 Mar; 378(Pt 3):1079-82. PubMed ID: 14690453
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Unique disulfide bonds in epidermal growth factor (EGF) domains of β3 affect structure and function of αIIbβ3 and αvβ3 integrins in different manner.
    Mor-Cohen R; Rosenberg N; Einav Y; Zelzion E; Landau M; Mansour W; Averbukh Y; Seligsohn U
    J Biol Chem; 2012 Mar; 287(12):8879-91. PubMed ID: 22308022
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Specific cysteines in beta3 are involved in disulfide bond exchange-dependent and -independent activation of alphaIIbbeta3.
    Mor-Cohen R; Rosenberg N; Landau M; Lahav J; Seligsohn U
    J Biol Chem; 2008 Jul; 283(28):19235-44. PubMed ID: 18458089
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The role of protein disulfide isomerase in the post-ligation phase of β3 integrin-dependent cell adhesion.
    Leader A; Mor-Cohen R; Ram R; Sheptovitsky V; Seligsohn U; Rosenberg N; Lahav J
    Thromb Res; 2015 Dec; 136(6):1259-65. PubMed ID: 26514956
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The novel S527F mutation in the integrin beta3 chain induces a high affinity alphaIIbbeta3 receptor by hindering adoption of the bent conformation.
    Vanhoorelbeke K; De Meyer SF; Pareyn I; Melchior C; Plançon S; Margue C; Pradier O; Fondu P; Kieffer N; Springer TA; Deckmyn H
    J Biol Chem; 2009 May; 284(22):14914-20. PubMed ID: 19329429
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A mutation in the extracellular cysteine-rich repeat region of the beta3 subunit activates integrins alphaIIbbeta3 and alphaVbeta3.
    Kashiwagi H; Tomiyama Y; Tadokoro S; Honda S; Shiraga M; Mizutani H; Handa M; Kurata Y; Matsuzawa Y; Shattil SJ
    Blood; 1999 Apr; 93(8):2559-68. PubMed ID: 10194435
    [TBL] [Abstract][Full Text] [Related]  

  • 7. β-Subunit Binding Is Sufficient for Ligands to Open the Integrin αIIbβ3 Headpiece.
    Lin FY; Zhu J; Eng ET; Hudson NE; Springer TA
    J Biol Chem; 2016 Feb; 291(9):4537-46. PubMed ID: 26631735
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A variant thrombasthenic phenotype associated with compound heterozygosity of integrin beta3-subunit: (Met124Val)beta3 alters the subunit dimerization rendering a decreased number of constitutive active alphaIIbbeta3 receptors.
    González-Manchón C; Butta N; Larrucea S; Arias-Salgado EG; Alonso S; López A; Parrilla R
    Thromb Haemost; 2004 Dec; 92(6):1377-86. PubMed ID: 15583747
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of critical residues for ligand binding in the integrin beta3 I-domain by site-directed mutagenesis.
    Yamanouchi J; Hato T; Tamura T; Fujita S
    Thromb Haemost; 2002 Apr; 87(4):756-62. PubMed ID: 12008962
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Abnormal cytoplasmic extensions associated with active αIIbβ3 are probably the cause for macrothrombocytopenia in Glanzmann thrombasthenia-like syndrome.
    Hauschner H; Mor-Cohen R; Messineo S; Mansour W; Seligsohn U; Savoia A; Rosenberg N
    Blood Coagul Fibrinolysis; 2015 Apr; 26(3):302-8. PubMed ID: 25806962
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A unique interaction between alphaIIb and beta3 in the head region is essential for outside-in signaling-related functions of alphaIIbbeta3 integrin.
    Hauschner H; Landau M; Seligsohn U; Rosenberg N
    Blood; 2010 Jun; 115(22):4542-50. PubMed ID: 20308600
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A naturally occurring point mutation in the beta3 integrin MIDAS-like domain affects differently alphavbeta3 and alphaIIIbbeta3 receptor function.
    Morel-Kopp MC; Melchior C; Chen P; Ammerlaan W; Lecompte T; Kaplan C; Kieffer N
    Thromb Haemost; 2001 Dec; 86(6):1425-34. PubMed ID: 11776310
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Study of signal transduction mediated by integrin alphaIIbbeta3 using a dominant negative model].
    Lu YJ; Su XY; Ruan Z; Xi XD
    Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2009 Aug; 17(4):1026-31. PubMed ID: 19698252
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The importance of N-glycosylation on β
    Cai X; Thinn AMM; Wang Z; Shan H; Zhu J
    Sci Rep; 2017 Jul; 7(1):4656. PubMed ID: 28680094
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Beta3 tyrosine phosphorylation in alphaIIbbeta3 (platelet membrane GP IIb-IIIa) outside-in integrin signaling.
    Phillips DR; Nannizzi-Alaimo L; Prasad KS
    Thromb Haemost; 2001 Jul; 86(1):246-58. PubMed ID: 11487013
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Roles of integrin β3 cytoplasmic tail in bidirectional signal transduction in a trans-dominant inhibition model.
    Huang J; Zhou Y; Su X; Lyu Y; Tao L; Shi X; Liu P; Long Z; Ruan Z; Xiao B; Xi W; Zhou Q; Mao J; Xi X
    Front Med; 2016 Sep; 10(3):311-9. PubMed ID: 27527361
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cooperative role of the membrane-proximal and -distal residues of the integrin beta3 cytoplasmic domain in regulation of talin-mediated alpha IIb beta3 activation.
    Hato T; Yamanouchi J; Tamura T; Yakushijin Y; Sakai I; Yasukawa M
    J Biol Chem; 2008 Feb; 283(9):5662-8. PubMed ID: 18174155
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tyr178 of beta3 is critical for alphaIIb maturation and macromolecular ligand binding to alphaIIbbeta3.
    Sun CX; Chen P; Lu W; Liu JN
    Thromb Res; 2008; 122(2):203-10. PubMed ID: 18201749
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Epigallocatechin gallate has pleiotropic effects on transmembrane signaling by altering the embedding of transmembrane domains.
    Ye F; Yang C; Kim J; MacNevin CJ; Hahn KM; Park D; Ginsberg MH; Kim C
    J Biol Chem; 2017 Jun; 292(24):9858-9864. PubMed ID: 28487468
    [TBL] [Abstract][Full Text] [Related]  

  • 20. An alternate covalent form of platelet αIIbβ3 integrin that resides in focal adhesions and has altered function.
    Pijning AE; Blyth MT; Coote ML; Passam F; Chiu J; Hogg PJ
    Blood; 2021 Oct; 138(15):1359-1372. PubMed ID: 34375384
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.