BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

191 related articles for article (PubMed ID: 14695178)

  • 1. Switching mechanisms of cell death in mdm2- and mdm4-null mice by deletion of p53 downstream targets.
    Chavez-Reyes A; Parant JM; Amelse LL; de Oca Luna RM; Korsmeyer SJ; Lozano G
    Cancer Res; 2003 Dec; 63(24):8664-9. PubMed ID: 14695178
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53.
    Parant J; Chavez-Reyes A; Little NA; Yan W; Reinke V; Jochemsen AG; Lozano G
    Nat Genet; 2001 Sep; 29(1):92-5. PubMed ID: 11528400
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutation at p53 serine 389 does not rescue the embryonic lethality in mdm2 or mdm4 null mice.
    Iwakuma T; Parant JM; Fasulo M; Zwart E; Jacks T; de Vries A; Lozano G
    Oncogene; 2004 Oct; 23(46):7644-50. PubMed ID: 15361844
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mdm4 (Mdmx) regulates p53-induced growth arrest and neuronal cell death during early embryonic mouse development.
    Migliorini D; Lazzerini Denchi E; Danovi D; Jochemsen A; Capillo M; Gobbi A; Helin K; Pelicci PG; Marine JC
    Mol Cell Biol; 2002 Aug; 22(15):5527-38. PubMed ID: 12101245
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Rescue of Mdm4-deficient mice by Mdm2 reveals functional overlap of Mdm2 and Mdm4 in development.
    Steinman HA; Hoover KM; Keeler ML; Sands AT; Jones SN
    Oncogene; 2005 Nov; 24(53):7935-40. PubMed ID: 16027727
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synergistic roles of Mdm2 and Mdm4 for p53 inhibition in central nervous system development.
    Xiong S; Van Pelt CS; Elizondo-Fraire AC; Liu G; Lozano G
    Proc Natl Acad Sci U S A; 2006 Feb; 103(9):3226-31. PubMed ID: 16492743
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tissue-specific differences of p53 inhibition by Mdm2 and Mdm4.
    Grier JD; Xiong S; Elizondo-Fraire AC; Parant JM; Lozano G
    Mol Cell Biol; 2006 Jan; 26(1):192-8. PubMed ID: 16354690
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The loss of mdm2 induces p53-mediated apoptosis.
    de Rozieres S; Maya R; Oren M; Lozano G
    Oncogene; 2000 Mar; 19(13):1691-7. PubMed ID: 10763826
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Absence of p21 partially rescues Mdm4 loss and uncovers an antiproliferative effect of Mdm4 on cell growth.
    Steinman HA; Sluss HK; Sands AT; Pihan G; Jones SN
    Oncogene; 2004 Jan; 23(1):303-6. PubMed ID: 14712235
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The p53 targets mdm2 and Fas are not required as mediators of apoptosis in vivo.
    Reinke V; Lozano G
    Oncogene; 1997 Sep; 15(13):1527-34. PubMed ID: 9380404
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mdm2 and Mdm4 loss regulates distinct p53 activities.
    Barboza JA; Iwakuma T; Terzian T; El-Naggar AK; Lozano G
    Mol Cancer Res; 2008 Jun; 6(6):947-54. PubMed ID: 18567799
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Haploinsufficiency of Mdm2 and Mdm4 in tumorigenesis and development.
    Terzian T; Wang Y; Van Pelt CS; Box NF; Travis EL; Lozano G
    Mol Cell Biol; 2007 Aug; 27(15):5479-85. PubMed ID: 17526734
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53.
    Montes de Oca Luna R; Wagner DS; Lozano G
    Nature; 1995 Nov; 378(6553):203-6. PubMed ID: 7477326
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mouse models of Mdm2 and Mdm4 and their clinical implications.
    Xiong S
    Chin J Cancer; 2013 Jul; 32(7):371-5. PubMed ID: 23327795
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A mouse p53 mutant lacking the proline-rich domain rescues Mdm4 deficiency and provides insight into the Mdm2-Mdm4-p53 regulatory network.
    Toledo F; Krummel KA; Lee CJ; Liu CW; Rodewald LW; Tang M; Wahl GM
    Cancer Cell; 2006 Apr; 9(4):273-85. PubMed ID: 16616333
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Genotoxic stress induces coordinately regulated alternative splicing of the p53 modulators MDM2 and MDM4.
    Chandler DS; Singh RK; Caldwell LC; Bitler JL; Lozano G
    Cancer Res; 2006 Oct; 66(19):9502-8. PubMed ID: 17018606
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Modulation of wild-type p53 activity by mutant p53 R273H depends on the p53 responsive element (p53RE). A comparative study between the p53REs of the MDM2, WAFI/Cip1 and Bax genes in the lung cancer environment. WAFI/Cip1 = WAF1/Cip1.
    Zacharatos PV; Gorgoulis VG; Kotsinas A; Manolis EN; Liloglou T; Rassidakis AN; Kanavaros P; Field JD; Halazonetis T; Kittas C
    Anticancer Res; 1999; 19(1A):579-87. PubMed ID: 10226602
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synergistic regulation of p53 by Mdm2 and Mdm4 is critical in cardiac endocardial cushion morphogenesis during heart development.
    Zhang Q; He X; Chen L; Zhang C; Gao X; Yang Z; Liu G
    J Pathol; 2012 Nov; 228(3):416-28. PubMed ID: 22821713
    [TBL] [Abstract][Full Text] [Related]  

  • 19. MDM4 (MDMX) overexpression enhances stabilization of stress-induced p53 and promotes apoptosis.
    Mancini F; Gentiletti F; D'Angelo M; Giglio S; Nanni S; D'Angelo C; Farsetti A; Citro G; Sacchi A; Pontecorvi A; Moretti F
    J Biol Chem; 2004 Feb; 279(9):8169-80. PubMed ID: 14660608
    [TBL] [Abstract][Full Text] [Related]  

  • 20. MDM2 expression during mouse embryogenesis and the requirement of p53.
    LĂ©veillard T; Gorry P; Niederreither K; Wasylyk B
    Mech Dev; 1998 Jun; 74(1-2):189-93. PubMed ID: 9651526
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.