These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 14695821)

  • 1. Design, synthesis, molecular modeling studies, and calpain inhibitory activity of novel alpha-ketoamides incorporating polar residues at the P1'-position.
    Donkor IO; Han J; Zheng X
    J Med Chem; 2004 Jan; 47(1):72-9. PubMed ID: 14695821
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel peptidyl alpha-keto amide inhibitors of calpains and other cysteine proteases.
    Li Z; Ortega-Vilain AC; Patil GS; Chu DL; Foreman JE; Eveleth DD; Powers JC
    J Med Chem; 1996 Sep; 39(20):4089-98. PubMed ID: 8831774
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis of cinnamoyl ketoamides as hybrid structures of antioxidants and calpain inhibitors.
    Yoo YJ; Nam DH; Jung SY; Jang JW; Kim HJ; Jin C; Pae AN; Lee YS
    Bioorg Med Chem Lett; 2011 May; 21(10):2850-4. PubMed ID: 21504847
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In-depth study of tripeptide-based alpha-ketoheterocycles as inhibitors of thrombin. Effective utilization of the S1' subsite and its implications to structure-based drug design.
    Costanzo MJ; Almond HR; Hecker LR; Schott MR; Yabut SC; Zhang HC; Andrade-Gordon P; Corcoran TW; Giardino EC; Kauffman JA; Lewis JM; de Garavilla L; Haertlein BJ; Maryanoff BE
    J Med Chem; 2005 Mar; 48(6):1984-2008. PubMed ID: 15771442
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Peptidyl alpha-ketoamides with nucleobases, methylpiperazine, and dimethylaminoalkyl substituents as calpain inhibitors.
    Ovat A; Li ZZ; Hampton CY; Asress SA; Fernández FM; Glass JD; Powers JC
    J Med Chem; 2010 Sep; 53(17):6326-36. PubMed ID: 20690647
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design and synthesis of 4-quinolinone 2-carboxamides as calpain inhibitors.
    Nam DH; Lee KS; Kim SH; Kim SM; Jung SY; Chung SH; Kim HJ; Kim ND; Jin C; Lee YS
    Bioorg Med Chem Lett; 2008 Jan; 18(1):205-9. PubMed ID: 18024028
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel peptidyl phosphorus derivatives as inhibitors of human calpain I.
    Tao M; Bihovsky R; Wells GJ; Mallamo JP
    J Med Chem; 1998 Sep; 41(20):3912-6. PubMed ID: 9748367
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Conformation of peptides constructed from achiral amino acid residues Aib and DeltaZPhe: computational study of the effect of L/D- Leu at terminal positions.
    Nandel FS; Khare B
    Biopolymers; 2005 Jan; 77(1):63-73. PubMed ID: 15593284
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis, calpain inhibitory activity, and cytotoxicity of P2-substituted proline and thiaproline peptidyl aldehydes and peptidyl alpha-ketoamides.
    Korukonda R; Guan N; Dalton JT; Liu J; Donkor IO
    J Med Chem; 2006 Aug; 49(17):5282-90. PubMed ID: 16913717
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Stereospecific synthesis of peptidyl alpha-keto amides as inhibitors of calpain.
    Harbeson SL; Abelleira SM; Akiyama A; Barrett R; Carroll RM; Straub JA; Tkacz JN; Wu C; Musso GF
    J Med Chem; 1994 Sep; 37(18):2918-29. PubMed ID: 8071940
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of putative agouti-related protein(87-132)-melanocortin-4 receptor interactions by homology molecular modeling and validation using chimeric peptide ligands.
    Wilczynski A; Wang XS; Joseph CG; Xiang Z; Bauzo RM; Scott JW; Sorensen NB; Shaw AM; Millard WJ; Richards NG; Haskell-Luevano C
    J Med Chem; 2004 Apr; 47(9):2194-207. PubMed ID: 15084118
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Efficacy of novel calpain inhibitors in preventing renal cell death.
    Harriman JF; Waters-Williams S; Chu DL; Powers JC; Schnellmann RG
    J Pharmacol Exp Ther; 2000 Sep; 294(3):1083-7. PubMed ID: 10945863
    [TBL] [Abstract][Full Text] [Related]  

  • 13. De novo design, synthesis, and pharmacology of alpha-melanocyte stimulating hormone analogues derived from somatostatin by a hybrid approach.
    Han G; Haskell-Luevano C; Kendall L; Bonner G; Hadley ME; Cone RD; Hruby VJ
    J Med Chem; 2004 Mar; 47(6):1514-26. PubMed ID: 14998337
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Design of potent, selective, and orally bioavailable inhibitors of cysteine protease cathepsin k.
    Tavares FX; Boncek V; Deaton DN; Hassell AM; Long ST; Miller AB; Payne AA; Miller LR; Shewchuk LM; Wells-Knecht K; Willard DH; Wright LL; Zhou HQ
    J Med Chem; 2004 Jan; 47(3):588-99. PubMed ID: 14736240
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Efficient synthesis of alpha-ketoamides via 2-acyl-5-aminooxazoles by reacting acyl chlorides and alpha-isocyanoacetamides.
    Mossetti R; Pirali T; Tron GC; Zhu J
    Org Lett; 2010 Feb; 12(4):820-3. PubMed ID: 20088495
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis, and metal binding of novel Pseudo- oligopeptides containing two phosphinic acid groups.
    Ye Y; Liu M; Kao JL; Marshall GR
    Biopolymers; 2008 Jan; 89(1):72-85. PubMed ID: 17910046
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis and biological evaluation of sugar-derived esters, alpha-ketoesters and alpha-ketoamides as inhibitors for Mycobacterium tuberculosis antigen 85C.
    Sanki AK; Boucau J; Umesiri FE; Ronning DR; Sucheck SJ
    Mol Biosyst; 2009 Sep; 5(9):945-56. PubMed ID: 19668859
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Hybrid alpha/beta3-peptides with proteinogenic side chains. Monosubstituted analogues of the chemotactic tripeptide For-Met-Leu-Phe-OMe.
    Giordano C; Lucente G; Mollica A; Nalli M; Pagani Zecchini G; Paglialunga Paradisi M; Gavuzzo E; Mazza F; Spisani S
    J Pept Sci; 2004 Aug; 10(8):510-23. PubMed ID: 15347138
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Introduction of non-natural amino acid residues into the substrate-specific P1 position of trypsin inhibitor SFTI-1 yields potent chymotrypsin and cathepsin G inhibitors.
    Łegowska A; Debowski D; Lesner A; Wysocka M; Rolka K
    Bioorg Med Chem; 2009 May; 17(9):3302-7. PubMed ID: 19362846
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Quantitative evaluation of each catalytic subsite of cathepsin B for inhibitory activity based on inhibitory activity-binding mode relationship of epoxysuccinyl inhibitors by X-ray crystal structure analyses of complexes.
    Watanabe D; Yamamoto A; Tomoo K; Matsumoto K; Murata M; Kitamura K; Ishida T
    J Mol Biol; 2006 Oct; 362(5):979-93. PubMed ID: 16950396
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.