BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

210 related articles for article (PubMed ID: 14695884)

  • 1. Directed evolution of mammalian paraoxonases PON1 and PON3 for bacterial expression and catalytic specialization.
    Aharoni A; Gaidukov L; Yagur S; Toker L; Silman I; Tawfik DS
    Proc Natl Acad Sci U S A; 2004 Jan; 101(2):482-7. PubMed ID: 14695884
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Directed evolution of serum paraoxonase PON3 by family shuffling and ancestor/consensus mutagenesis, and its biochemical characterization.
    Khersonsky O; Rosenblat M; Toker L; Yacobson S; Hugenmatter A; Silman I; Sussman JL; Aviram M; Tawfik DS
    Biochemistry; 2009 Jul; 48(28):6644-54. PubMed ID: 19492856
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes.
    Harel M; Aharoni A; Gaidukov L; Brumshtein B; Khersonsky O; Meged R; Dvir H; Ravelli RB; McCarthy A; Toker L; Silman I; Sussman JL; Tawfik DS
    Nat Struct Mol Biol; 2004 May; 11(5):412-9. PubMed ID: 15098021
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-reactivity studies of serum paraoxonase PON1 suggest that its native activity is lactonase.
    Khersonsky O; Tawfik DS
    Biochemistry; 2005 Apr; 44(16):6371-82. PubMed ID: 15835926
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Estrogen esters as substrates for human paraoxonases.
    Teiber JF; Billecke SS; La Du BN; Draganov DI
    Arch Biochem Biophys; 2007 May; 461(1):24-9. PubMed ID: 17412306
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Directed evolution of recombinant serum paraoxonase (PON) variants.
    Aharoni A; Tawfik DS
    Discov Med; 2004 Apr; 4(21):120-4. PubMed ID: 20705007
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Expression and purification of biologically active recombinant human paraoxonase 1 from inclusion bodies of Escherichia coli.
    Bajaj P; Tripathy RK; Aggarwal G; Pande AH
    Protein Expr Purif; 2015 Nov; 115():95-101. PubMed ID: 26003526
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Altering the substrate specificity of organophosphorus hydrolase for enhanced hydrolysis of chlorpyrifos.
    Cho CM; Mulchandani A; Chen W
    Appl Environ Microbiol; 2004 Aug; 70(8):4681-5. PubMed ID: 15294802
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Directed evolution of sulfotransferases and paraoxonases by ancestral libraries.
    Alcolombri U; Elias M; Tawfik DS
    J Mol Biol; 2011 Aug; 411(4):837-53. PubMed ID: 21723874
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The Structure and Function of Paraoxonase-1 and Its Comparison to Paraoxonase-2 and -3.
    Taler-Verčič A; Goličnik M; Bavec A
    Molecules; 2020 Dec; 25(24):. PubMed ID: 33348669
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Paraoxonases-1, -2 and -3: What are their functions?
    Furlong CE; Marsillach J; Jarvik GP; Costa LG
    Chem Biol Interact; 2016 Nov; 259(Pt B):51-62. PubMed ID: 27238723
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The evolutionary origins of detoxifying enzymes: the mammalian serum paraoxonases (PONs) relate to bacterial homoserine lactonases.
    Bar-Rogovsky H; Hugenmatter A; Tawfik DS
    J Biol Chem; 2013 Aug; 288(33):23914-27. PubMed ID: 23788644
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of biologically active δ-lactone eicosanoids as paraoxonase substrates.
    Teiber JF; Xiao J; Kramer GL; Ogawa S; Ebner C; Wolleb H; Carreira EM; Shih DM; Haley RW
    Biochem Biophys Res Commun; 2018 Oct; 505(1):87-92. PubMed ID: 30241945
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Asymmetric fluorogenic organophosphates for the development of active organophosphate hydrolases with reversed stereoselectivity.
    Amitai G; Adani R; Yacov G; Yishay S; Teitlboim S; Tveria L; Limanovich O; Kushnir M; Meshulam H
    Toxicology; 2007 Apr; 233(1-3):187-98. PubMed ID: 17129656
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Human paraoxonase 1 as a pharmacologic agent: limitations and perspectives.
    Bajaj P; Tripathy RK; Aggarwal G; Pande AH
    ScientificWorldJournal; 2014; 2014():854391. PubMed ID: 25386619
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Enhanced stereoselective hydrolysis of toxic organophosphates by directly evolved variants of mammalian serum paraoxonase.
    Amitai G; Gaidukov L; Adani R; Yishay S; Yacov G; Kushnir M; Teitlboim S; Lindenbaum M; Bel P; Khersonsky O; Tawfik DS; Meshulam H
    FEBS J; 2006 May; 273(9):1906-19. PubMed ID: 16640555
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Paraoxonases (PON1, PON2, PON3) analyses in vitro and in vivo in relation to cardiovascular diseases.
    Aviram M; Rosenblat M
    Methods Mol Biol; 2008; 477():259-76. PubMed ID: 19082953
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional analysis of organophosphorus hydrolase variants with high degradation activity towards organophosphate pesticides.
    Mee-Hie Cho C; Mulchandani A; Chen W
    Protein Eng Des Sel; 2006 Mar; 19(3):99-105. PubMed ID: 16423845
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Toward Understanding the Catalytic Mechanism of Human Paraoxonase 1: Site-Specific Mutagenesis at Position 192.
    Aggarwal G; Prajapati R; Tripathy RK; Bajaj P; Iyengar AR; Sangamwar AT; Pande AH
    PLoS One; 2016; 11(2):e0147999. PubMed ID: 26829396
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 3-D structure of serum paraoxonase 1 sheds light on its activity, stability, solubility and crystallizability.
    Harel M; Brumshtein B; Meged R; Dvir H; Ravelli RB; McCarthy A; Toker L; Silman I; Sussman JL
    Arh Hig Rada Toksikol; 2007 Sep; 58(3):347-53. PubMed ID: 17913690
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.