185 related articles for article (PubMed ID: 14697345)
1. Sphingomyelin synthase as a potential target for D609-induced apoptosis in U937 human monocytic leukemia cells.
Meng A; Luberto C; Meier P; Bai A; Yang X; Hannun YA; Zhou D
Exp Cell Res; 2004 Jan; 292(2):385-92. PubMed ID: 14697345
[TBL] [Abstract][Full Text] [Related]
2. Sphingomyelin synthase, a potential regulator of intracellular levels of ceramide and diacylglycerol during SV40 transformation. Does sphingomyelin synthase account for the putative phosphatidylcholine-specific phospholipase C?
Luberto C; Hannun YA
J Biol Chem; 1998 Jun; 273(23):14550-9. PubMed ID: 9603970
[TBL] [Abstract][Full Text] [Related]
3. Induction of apoptosis and potentiation of TNF- and Fas-mediated apoptosis in U937 cells by the xanthogenate compound D609.
Pörn-Ares MI; Chow SC; Slotte JP; Orrenius S
Exp Cell Res; 1997 Aug; 235(1):48-54. PubMed ID: 9281351
[TBL] [Abstract][Full Text] [Related]
4. Anti-proliferative effects of tricyclodecan-9-yl-xanthogenate (D609) involve ceramide and cell cycle inhibition.
Gusain A; Hatcher JF; Adibhatla RM; Wesley UV; Dempsey RJ
Mol Neurobiol; 2012 Jun; 45(3):455-64. PubMed ID: 22415444
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of sphingomyelin synthase (SMS) affects intracellular sphingomyelin accumulation and plasma membrane lipid organization.
Li Z; Hailemariam TK; Zhou H; Li Y; Duckworth DC; Peake DA; Zhang Y; Kuo MS; Cao G; Jiang XC
Biochim Biophys Acta; 2007 Sep; 1771(9):1186-94. PubMed ID: 17616479
[TBL] [Abstract][Full Text] [Related]
6. Prodrug modification increases potassium tricyclo[5.2.1.0(2,6)]-decan-8-yl dithiocarbonate (D609) chemical stability and cytotoxicity against U937 leukemia cells.
Bai A; Meier GP; Wang Y; Luberto C; Hannun YA; Zhou D
J Pharmacol Exp Ther; 2004 Jun; 309(3):1051-9. PubMed ID: 14960662
[TBL] [Abstract][Full Text] [Related]
7. The tricyclodecan-9-yl-xanthogenate D609 triggers ceramide increase and enhances FasL-induced caspase-dependent and -independent cell death in T lymphocytes.
Milhas D; Andrieu-Abadie N; Levade T; Benoist H; Ségui B
Int J Mol Sci; 2012; 13(7):8834-8852. PubMed ID: 22942738
[TBL] [Abstract][Full Text] [Related]
8. Effect of tricyclodecan-9-yl potassium xanthate (D609) on phospholipid metabolism and cell death during oxygen-glucose deprivation in PC12 cells.
Larsen EC; Hatcher JF; Adibhatla RM
Neuroscience; 2007 May; 146(3):946-61. PubMed ID: 17434680
[TBL] [Abstract][Full Text] [Related]
9. Role of diacylglycerol induced by hypoxia in the regulation of HIF-1alpha activity.
Temes E; Martín-Puig S; Aragonés J; Jones DR; Olmos G; Mérida I; Landázuri MO
Biochem Biophys Res Commun; 2004 Feb; 315(1):44-50. PubMed ID: 15013423
[TBL] [Abstract][Full Text] [Related]
10. The role of de novo ceramide synthesis in the mechanism of action of the tricyclic xanthate D609.
Perry RJ; Ridgway ND
J Lipid Res; 2004 Jan; 45(1):164-73. PubMed ID: 13130125
[TBL] [Abstract][Full Text] [Related]
11. Role of sphingomyelin synthesis in pulmonary endothelial cell cytoskeletal activation and endotoxin-induced lung injury.
Anjum F; Joshi K; Grinkina N; Gowda S; Cutaia M; Wadgaonkar R
Am J Respir Cell Mol Biol; 2012 Jul; 47(1):94-103. PubMed ID: 22362386
[TBL] [Abstract][Full Text] [Related]
12. Sphingomyelin synthase 1 activity is regulated by the BCR-ABL oncogene.
Burns TA; Subathra M; Signorelli P; Choi Y; Yang X; Wang Y; Villani M; Bhalla K; Zhou D; Luberto C
J Lipid Res; 2013 Mar; 54(3):794-805. PubMed ID: 23160178
[TBL] [Abstract][Full Text] [Related]
13. Tricyclodecan-9-yl-xanthogenate (D609) mechanism of actions: a mini-review of literature.
Adibhatla RM; Hatcher JF; Gusain A
Neurochem Res; 2012 Apr; 37(4):671-9. PubMed ID: 22101393
[TBL] [Abstract][Full Text] [Related]
14. Tricyclodecan-9-yl-Xanthogenate (D609): Mechanism of Action and Pharmacological Applications.
Bhat AH; Dar KB; Khan A; Alshahrani S; Alshehri SM; Ghoneim MM; Alam P; Shakeel F
Int J Mol Sci; 2022 Mar; 23(6):. PubMed ID: 35328726
[TBL] [Abstract][Full Text] [Related]
15. Mitochondrial ceramide increases in UV-irradiated HeLa cells and is mainly derived from hydrolysis of sphingomyelin.
Dai Q; Liu J; Chen J; Durrant D; McIntyre TM; Lee RM
Oncogene; 2004 Apr; 23(20):3650-8. PubMed ID: 15077187
[TBL] [Abstract][Full Text] [Related]
16. Daunorubicin- and mitoxantrone-triggered phosphatidylcholine hydrolysis: implication in drug-induced ceramide generation and apoptosis.
Bettaïeb A; Plo I; Mansat-De Mas V; Quillet-Mary A; Levade T; Laurent G; Jaffrézou JP
Mol Pharmacol; 1999 Jan; 55(1):118-25. PubMed ID: 9882705
[TBL] [Abstract][Full Text] [Related]
17. Differential effects of sphingomyelin hydrolysis and resynthesis on the activation of NF-kappa B in normal and SV40-transformed human fibroblasts.
Luberto C; Yoo DS; Suidan HS; Bartoli GM; Hannun YA
J Biol Chem; 2000 May; 275(19):14760-6. PubMed ID: 10799564
[TBL] [Abstract][Full Text] [Related]
18. Increase of nuclear ceramide through caspase-3-dependent regulation of the "sphingomyelin cycle" in Fas-induced apoptosis.
Watanabe M; Kitano T; Kondo T; Yabu T; Taguchi Y; Tashima M; Umehara H; Domae N; Uchiyama T; Okazaki T
Cancer Res; 2004 Feb; 64(3):1000-7. PubMed ID: 14871831
[TBL] [Abstract][Full Text] [Related]
19. Sphingomyelin synthase activity affects TRIF-dependent signaling of Toll-like receptor 4 in cells stimulated with lipopolysaccharide.
Prymas K; Świątkowska A; Traczyk G; Ziemlińska E; Dziewulska A; Ciesielska A; Kwiatkowska K
Biochim Biophys Acta Mol Cell Biol Lipids; 2020 Feb; 1865(2):158549. PubMed ID: 31678513
[TBL] [Abstract][Full Text] [Related]
20. Ceramide does not inhibit protein kinase C beta-dependent phospholipase D activity stimulated by anti-Fas monoclonal antibody in A20 cells.
Han J; Shin I
Cell Signal; 2000 Dec; 12(11-12):731-6. PubMed ID: 11152958
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]