These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. The first potent and selective inhibitors of the glycine transporter type 2. Caulfield WL; Collie IT; Dickins RS; Epemolu O; McGuire R; Hill DR; McVey G; Morphy JR; Rankovic Z; Sundaram H J Med Chem; 2001 Aug; 44(17):2679-82. PubMed ID: 11495577 [No Abstract] [Full Text] [Related]
3. Design, synthesis, and SAR of N-((1-(4-(propylsulfonyl)piperazin-1-yl)cycloalkyl)methyl)benzamide inhibitors of glycine transporter-1. Cioffi CL; Wolf MA; Guzzo PR; Sadalapure K; Parthasarathy V; Dethe D; Maeng JH; Carulli E; Loong DT; Fang X; Hu M; Gupta P; Chung M; Bai M; Moore N; Luche M; Khmelnitsky Y; Love PL; Watson MA; Mhyre AJ; Liu S Bioorg Med Chem Lett; 2013 Mar; 23(5):1257-61. PubMed ID: 23380375 [TBL] [Abstract][Full Text] [Related]
5. Synthesis and Biological Evaluation of N-((1-(4-(Sulfonyl)piperazin-1-yl)cycloalkyl)methyl)benzamide Inhibitors of Glycine Transporter-1. Cioffi CL; Liu S; Wolf MA; Guzzo PR; Sadalapure K; Parthasarathy V; Loong DT; Maeng JH; Carulli E; Fang X; Karunakaran K; Matta L; Choo SH; Panduga S; Buckle RN; Davis RN; Sakwa SA; Gupta P; Sargent BJ; Moore NA; Luche MM; Carr GJ; Khmelnitsky YL; Ismail J; Chung M; Bai M; Leong WY; Sachdev N; Swaminathan S; Mhyre AJ J Med Chem; 2016 Sep; 59(18):8473-94. PubMed ID: 27559615 [TBL] [Abstract][Full Text] [Related]
6. The discovery of potent glycine transporter type-2 inhibitors: design and synthesis of phenoxymethylbenzamide derivatives. Takahashi E; Arai T; Akahira M; Nakajima M; Nishimura K; Omori Y; Kumagai H; Suzuki T; Hayashi R Bioorg Med Chem Lett; 2014 Sep; 24(18):4603-4606. PubMed ID: 25176190 [TBL] [Abstract][Full Text] [Related]
7. Novel glycine transporter type-2 reuptake inhibitors. Part 2: beta- and gamma-amino acid derivatives. Wolin RL; Santillán A; Barclay T; Tang L; Venkatesan H; Wilson S; Lee DH; Lovenberg TW Bioorg Med Chem; 2004 Aug; 12(16):4493-509. PubMed ID: 15265499 [TBL] [Abstract][Full Text] [Related]
8. Inhibitors of GlyT1 affect glycine transport via discrete binding sites. Mezler M; Hornberger W; Mueller R; Schmidt M; Amberg W; Braje W; Ochse M; Schoemaker H; Behl B Mol Pharmacol; 2008 Dec; 74(6):1705-15. PubMed ID: 18815213 [TBL] [Abstract][Full Text] [Related]
9. Pharmacology and expression analysis of glycine transporter GlyT1 with [3H]-(N-[3-(4'-fluorophenyl)-3-(4'phenylphenoxy)propyl])sarcosine. Mallorga PJ; Williams JB; Jacobson M; Marques R; Chaudhary A; Conn PJ; Pettibone DJ; Sur C Neuropharmacology; 2003 Oct; 45(5):585-93. PubMed ID: 12941372 [TBL] [Abstract][Full Text] [Related]
10. ALX 5407: a potent, selective inhibitor of the hGlyT1 glycine transporter. Atkinson BN; Bell SC; De Vivo M; Kowalski LR; Lechner SM; Ognyanov VI; Tham CS; Tsai C; Jia J; Ashton D; Klitenick MA Mol Pharmacol; 2001 Dec; 60(6):1414-20. PubMed ID: 11723250 [TBL] [Abstract][Full Text] [Related]
11. Positive N-methyl-D-aspartate receptor modulation by selective glycine transporter-1 inhibition in the rat dorsal spinal cord in vivo. Whitehead KJ; Pearce SM; Walker G; Sundaram H; Hill D; Bowery NG Neuroscience; 2004; 126(2):381-90. PubMed ID: 15207356 [TBL] [Abstract][Full Text] [Related]
12. The glycine transporter-1 inhibitors NFPS and Org 24461: a pharmacological study. Harsing LG; Gacsalyi I; Szabo G; Schmidt E; Sziray N; Sebban C; Tesolin-Decros B; Matyus P; Egyed A; Spedding M; Levay G Pharmacol Biochem Behav; 2003 Mar; 74(4):811-25. PubMed ID: 12667895 [TBL] [Abstract][Full Text] [Related]
13. Glycine transporter isoforms in the mammalian central nervous system: structures, functions and therapeutic promises. Gomeza J; Ohno K; Betz H Curr Opin Drug Discov Devel; 2003 Sep; 6(5):675-82. PubMed ID: 14579517 [TBL] [Abstract][Full Text] [Related]
14. The synthesis and SAR of 2-arylsulfanyl-phenyl piperazinyl acetic acids as glyT-1 inhibitors. Smith G; Ruhland T; Mikkelsen G; Andersen K; Christoffersen CT; Alifrangis LH; Mørk A; Wren SP; Harris N; Wyman BM; Brandt G Bioorg Med Chem Lett; 2004 Aug; 14(15):4027-30. PubMed ID: 15225720 [TBL] [Abstract][Full Text] [Related]
15. Inhibitors of the glycine transporter type-2 (GlyT-2): synthesis and biological activity of benzoylpiperidine derivatives. Wolin RL; Santillán A; Tang L; Huang C; Jiang X; Lovenberg TW Bioorg Med Chem; 2004 Aug; 12(16):4511-32. PubMed ID: 15265500 [TBL] [Abstract][Full Text] [Related]
16. In vivo characterization of changes in glycine levels induced by GlyT1 inhibitors. Johnson KW; Clemens-Smith A; Nomikos G; Davis R; Phebus L; Shannon H; Love P; Perry K; Katner J; Bymaster F; Yu H; Hoffman BJ Ann N Y Acad Sci; 2003 Nov; 1003():412-4. PubMed ID: 14684475 [No Abstract] [Full Text] [Related]
17. N[3-(4'-fluorophenyl)-3-(4'-phenylphenoxy)propyl]sarcosine (NFPS) is a selective persistent inhibitor of glycine transport. Aubrey KR; Vandenberg RJ Br J Pharmacol; 2001 Dec; 134(7):1429-36. PubMed ID: 11724748 [TBL] [Abstract][Full Text] [Related]
18. Development of a scintillation proximity assay for analysis of Na+/Cl- -dependent neurotransmitter transporter activity. Williams JB; Mallorga PJ; Lemaire W; Williams DL; Na S; Patel S; Conn PJ; Pettibone DJ; Austin C; Sur C Anal Biochem; 2003 Oct; 321(1):31-7. PubMed ID: 12963052 [TBL] [Abstract][Full Text] [Related]
19. Membrane glycine transport proteins. Tunnicliff G J Biomed Sci; 2003; 10(1):30-6. PubMed ID: 12566983 [TBL] [Abstract][Full Text] [Related]
20. Irreversible inhibition of [3H]glycine transport into channel catfish erythrocytes by thiol group modifiers. McCormick SJ; Tunnicliff G Pharmacology; 2004 Mar; 70(3):113-7. PubMed ID: 14752230 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]