311 related articles for article (PubMed ID: 14705926)
1. Picomolar transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase and X-ray structure with MT-immucillin-A.
Singh V; Shi W; Evans GB; Tyler PC; Furneaux RH; Almo SC; Schramm VL
Biochemistry; 2004 Jan; 43(1):9-18. PubMed ID: 14705926
[TBL] [Abstract][Full Text] [Related]
2. Over-the-barrier transition state analogues and crystal structure with Mycobacterium tuberculosis purine nucleoside phosphorylase.
Lewandowicz A; Shi W; Evans GB; Tyler PC; Furneaux RH; Basso LA; Santos DS; Almo SC; Schramm VL
Biochemistry; 2003 May; 42(20):6057-66. PubMed ID: 12755607
[TBL] [Abstract][Full Text] [Related]
3. One-third-the-sites transition-state inhibitors for purine nucleoside phosphorylase.
Miles RW; Tyler PC; Furneaux RH; Bagdassarian CK; Schramm VL
Biochemistry; 1998 Jun; 37(24):8615-21. PubMed ID: 9628722
[TBL] [Abstract][Full Text] [Related]
4. Targeting the polyamine pathway with transition-state analogue inhibitors of 5'-methylthioadenosine phosphorylase.
Evans GB; Furneaux RH; Schramm VL; Singh V; Tyler PC
J Med Chem; 2004 Jun; 47(12):3275-81. PubMed ID: 15163207
[TBL] [Abstract][Full Text] [Related]
5. Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase.
Kicska GA; Tyler PC; Evans GB; Furneaux RH; Shi W; Fedorov A; Lewandowicz A; Cahill SM; Almo SC; Schramm VL
Biochemistry; 2002 Dec; 41(49):14489-98. PubMed ID: 12463747
[TBL] [Abstract][Full Text] [Related]
6. Ionic states of substrates and transition state analogues at the catalytic sites of N-ribosyltransferases.
Sauve AA; Cahill SM; Zech SG; Basso LA; Lewandowicz A; Santos DS; Grubmeyer C; Evans GB; Furneaux RH; Tyler PC; McDermott A; Girvin ME; Schramm VL
Biochemistry; 2003 May; 42(19):5694-705. PubMed ID: 12741826
[TBL] [Abstract][Full Text] [Related]
7. Structural rationale for the affinity of pico- and femtomolar transition state analogues of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.
Lee JE; Singh V; Evans GB; Tyler PC; Furneaux RH; Cornell KA; Riscoe MK; Schramm VL; Howell PL
J Biol Chem; 2005 May; 280(18):18274-82. PubMed ID: 15746096
[TBL] [Abstract][Full Text] [Related]
8. Femtomolar transition state analogue inhibitors of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Escherichia coli.
Singh V; Evans GB; Lenz DH; Mason JM; Clinch K; Mee S; Painter GF; Tyler PC; Furneaux RH; Lee JE; Howell PL; Schramm VL
J Biol Chem; 2005 May; 280(18):18265-73. PubMed ID: 15749708
[TBL] [Abstract][Full Text] [Related]
9. Synthesis of second-generation transition state analogues of human purine nucleoside phosphorylase.
Evans GB; Furneaux RH; Lewandowicz A; Schramm VL; Tyler PC
J Med Chem; 2003 Nov; 46(24):5271-6. PubMed ID: 14613329
[TBL] [Abstract][Full Text] [Related]
10. Assignment of downfield proton resonances in purine nucleoside phosphorylase immucillin-H complex by saturation-transferred NOEs.
Deng H; Lewandowicz A; Cahill SM; Furneaux RH; Tyler PC; Girvin ME; Callender RH; Schramm VL
Biochemistry; 2004 Feb; 43(7):1980-7. PubMed ID: 14967038
[TBL] [Abstract][Full Text] [Related]
11. Inhibition and structure of Trichomonas vaginalis purine nucleoside phosphorylase with picomolar transition state analogues.
Rinaldo-Matthis A; Wing C; Ghanem M; Deng H; Wu P; Gupta A; Tyler PC; Evans GB; Furneaux RH; Almo SC; Wang CC; Schramm VL
Biochemistry; 2007 Jan; 46(3):659-68. PubMed ID: 17223688
[TBL] [Abstract][Full Text] [Related]
12. Azetidine based transition state analogue inhibitors of N-ribosyl hydrolases and phosphorylases.
Evans GB; Furneaux RH; Greatrex B; Murkin AS; Schramm VL; Tyler PC
J Med Chem; 2008 Feb; 51(4):948-56. PubMed ID: 18251493
[TBL] [Abstract][Full Text] [Related]
13. Purine nucleoside phosphorylase from Mycobacterium tuberculosis. Analysis of inhibition by a transition-state analogue and dissection by parts.
Basso LA; Santos DS; Shi W; Furneaux RH; Tyler PC; Schramm VL; Blanchard JS
Biochemistry; 2001 Jul; 40(28):8196-203. PubMed ID: 11444965
[TBL] [Abstract][Full Text] [Related]
14. Exploring structure-activity relationships of transition state analogues of human purine nucleoside phosphorylase.
Evans GB; Furneaux RH; Lewandowicz A; Schramm VL; Tyler PC
J Med Chem; 2003 Jul; 46(15):3412-23. PubMed ID: 12852771
[TBL] [Abstract][Full Text] [Related]
15. Structure and inhibition of a quorum sensing target from Streptococcus pneumoniae.
Singh V; Shi W; Almo SC; Evans GB; Furneaux RH; Tyler PC; Painter GF; Lenz DH; Mee S; Zheng R; Schramm VL
Biochemistry; 2006 Oct; 45(43):12929-41. PubMed ID: 17059210
[TBL] [Abstract][Full Text] [Related]
16. 1.45 A resolution crystal structure of recombinant PNP in complex with a pM multisubstrate analogue inhibitor bearing one feature of the postulated transition state.
Chojnowski G; Breer K; Narczyk M; Wielgus-Kutrowska B; Czapinska H; Hashimoto M; Hikishima S; Yokomatsu T; Bochtler M; Girstun A; StaroĊ K; Bzowska A
Biochem Biophys Res Commun; 2010 Jan; 391(1):703-8. PubMed ID: 19944078
[TBL] [Abstract][Full Text] [Related]
17. Enzymatic transition states: thermodynamics, dynamics and analogue design.
Schramm VL
Arch Biochem Biophys; 2005 Jan; 433(1):13-26. PubMed ID: 15581562
[TBL] [Abstract][Full Text] [Related]
18. Four generations of transition-state analogues for human purine nucleoside phosphorylase.
Ho MC; Shi W; Rinaldo-Matthis A; Tyler PC; Evans GB; Clinch K; Almo SC; Schramm VL
Proc Natl Acad Sci U S A; 2010 Mar; 107(11):4805-12. PubMed ID: 20212140
[TBL] [Abstract][Full Text] [Related]
19. L-Enantiomers of transition state analogue inhibitors bound to human purine nucleoside phosphorylase.
Rinaldo-Matthis A; Murkin AS; Ramagopal UA; Clinch K; Mee SP; Evans GB; Tyler PC; Furneaux RH; Almo SC; Schramm VL
J Am Chem Soc; 2008 Jan; 130(3):842-4. PubMed ID: 18154341
[TBL] [Abstract][Full Text] [Related]
20. 8-Aza-immucillins as transition-state analogue inhibitors of purine nucleoside phosphorylase and nucleoside hydrolases.
Evans GB; Furneaux RH; Gainsford GJ; Hanson JC; Kicska GA; Sauve AA; Schramm VL; Tyler PC
J Med Chem; 2003 Jan; 46(1):155-60. PubMed ID: 12502369
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
