BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

112 related articles for article (PubMed ID: 14706649)

  • 1. A trans-Golgi network retention signal YQRL fused to ricin A chain significantly enhances its cytotoxicity.
    Zhan J; Ge L; Shen J; Wang K; Zheng S
    Biochem Biophys Res Commun; 2004 Jan; 313(4):1053-7. PubMed ID: 14706649
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Modification of ricin A chain, by addition of endoplasmic reticulum (KDEL) or Golgi (YQRL) retention sequences, enhances its cytotoxicity and translocation.
    Zhan J; Stayton P; Press OW
    Cancer Immunol Immunother; 1998 Mar; 46(1):55-60. PubMed ID: 9520293
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Expression of ricin A chain and ricin A chain-KDEL in Escherichia coli.
    Zhan J; Chen Y; Wang K; Zheng S
    Protein Expr Purif; 2004 Apr; 34(2):197-201. PubMed ID: 15003251
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cytotoxicity of KDEL-terminated ricin toxins correlates with distribution of the KDEL receptor in the Golgi.
    Tagge E; Chandler J; Tang BL; Hong W; Willingham MC; Frankel A
    J Histochem Cytochem; 1996 Feb; 44(2):159-65. PubMed ID: 8609372
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ricin A chain reaches the endoplasmic reticulum after endocytosis.
    Liu Q; Zhan J; Chen X; Zheng S
    Biochem Biophys Res Commun; 2006 May; 343(3):857-63. PubMed ID: 16564502
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [Study on lysosomes degradation of ricin A chain].
    Chen C; Zhan JB; Shen FP; Shen JG
    Zhejiang Da Xue Xue Bao Yi Xue Ban; 2005 May; 34(3):212-6. PubMed ID: 15940786
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Addition of an endoplasmic reticulum retrieval sequence to ricin A chain significantly increases its cytotoxicity to mammalian cells.
    Wales R; Roberts LM; Lord JM
    J Biol Chem; 1993 Nov; 268(32):23986-90. PubMed ID: 8226941
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Generation of a potent chimeric toxin by replacement of domain III of Pseudomonas exotoxin with ricin A chain KDEL.
    Pitcher C; Roberts L; Fawell S; Zdanovsky AG; FitzGerald DJ; Lord JM
    Bioconjug Chem; 1995; 6(5):624-9. PubMed ID: 8974463
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Endosome to Golgi transport of ricin is independent of clathrin and of the Rab9- and Rab11-GTPases.
    Iversen TG; Skretting G; Llorente A; Nicoziani P; van Deurs B; Sandvig K
    Mol Biol Cell; 2001 Jul; 12(7):2099-107. PubMed ID: 11452006
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Catalytic and cytotoxic activities of recombinant ricin A chain mutants with charged residues added at the carboxyl terminus.
    Simpson JC; Roberts LM; Lord JM
    Protein Expr Purif; 1995 Oct; 6(5):665-70. PubMed ID: 8535160
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The signal peptide NPFSD fused to ricin A chain enhances cell uptake and cytotoxicity in Candida albicans.
    Rajarao GK; Nekhotiaeva N; Good L
    Biochem Biophys Res Commun; 2003 Feb; 301(2):529-34. PubMed ID: 12565894
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Self-potentiation of ligand-toxin conjugates containing ricin A chain fused with viral structures.
    Chignola R; Anselmi C; Dalla Serra M; Franceschi A; Fracasso G; Pasti M; Chiesa E; Lord JM; Tridente G; Colombatti M
    J Biol Chem; 1995 Oct; 270(40):23345-51. PubMed ID: 7559491
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differences in cytotoxicity of native and engineered RIPs can be used to assess their ability to reach the cytoplasm.
    Svinth M; Steighardt J; Hernandez R; Suh JK; Kelly C; Day P; Lord M; Girbes T; Robertus JD
    Biochem Biophys Res Commun; 1998 Aug; 249(3):637-42. PubMed ID: 9731188
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization of a ricin fusion toxin targeted to the interleukin-2 receptor.
    Frankel AE; Burbage C; Fu T; Tagge E; Chandler J; Willingham M
    Protein Eng; 1996 Oct; 9(10):913-9. PubMed ID: 8931131
    [TBL] [Abstract][Full Text] [Related]  

  • 15. [Construction and expression of ricin A chain and green fluorescent protein fusion gene in E. coli].
    Chen XH; Liu Q; Zhan JB
    Zhejiang Da Xue Xue Bao Yi Xue Ban; 2005 May; 34(3):201-6. PubMed ID: 15940784
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Construction and characterization of the recombinant immunotoxin RTA-4D5-KDEL targeting HER2/neu-positive cancer cells and locating the endoplasmic reticulum.
    Jiao P; Zhang J; Dong Y; Wei D; Ren Y
    Appl Microbiol Biotechnol; 2018 Nov; 102(22):9585-9594. PubMed ID: 30141083
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Co-application of ricin A chain and a recombinant adenovirus expressing ricin B chain as a novel approach for cancer therapy.
    Wang HB; Xia F; Ge J; Yin J; Tan LS; Zhang PD; Zhong J
    Acta Pharmacol Sin; 2007 May; 28(5):657-62. PubMed ID: 17439722
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ricin fusion toxin targeted to the human granulocyte-macrophage colony stimulating factor receptor is selectively toxic to acute myeloid leukemia cells.
    Burbage C; Tagge EP; Harris B; Hall P; Fu T; Willingham MC; Frankel AE
    Leuk Res; 1997 Jul; 21(7):681-90. PubMed ID: 9301690
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Addition of an ER retention signal to the ricin A chain increases the cytotoxicity of the holotoxin.
    Wales R; Chaddock JA; Roberts LM; Lord JM
    Exp Cell Res; 1992 Nov; 203(1):1-4. PubMed ID: 1426032
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis of green fluorescent protein-ricin and monitoring of its intracellular trafficking.
    Tagge E; Harris B; Burbage C; Hall P; Vesely J; Willingham M; Frankel A
    Bioconjug Chem; 1997; 8(5):743-50. PubMed ID: 9327140
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.