These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

130 related articles for article (PubMed ID: 14706820)

  • 1. Engineering the serine/threonine protein kinase Raf-1 to utilise an orthogonal analogue of ATP substituted at the N6 position.
    Hindley AD; Park S; Wang L; Shah K; Wang Y; Hu X; Shokat KM; Kolch W; Sedivy JM; Yeung KC
    FEBS Lett; 2004 Jan; 556(1-3):26-34. PubMed ID: 14706820
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Regulation of the Raf kinase by phosphorylation.
    Zhang BH; Guan KL
    Exp Lung Res; 2001; 27(3):269-95. PubMed ID: 11293329
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Different effects of point mutations within the B-Raf glycine-rich loop in colorectal tumors on mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase and nuclear factor kappaB pathway and cellular transformation.
    Ikenoue T; Hikiba Y; Kanai F; Aragaki J; Tanaka Y; Imamura J; Imamura T; Ohta M; Ijichi H; Tateishi K; Kawakami T; Matsumura M; Kawabe T; Omata M
    Cancer Res; 2004 May; 64(10):3428-35. PubMed ID: 15150094
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Engineering Src family protein kinases with unnatural nucleotide specificity.
    Liu Y; Shah K; Yang F; Witucki L; Shokat KM
    Chem Biol; 1998 Feb; 5(2):91-101. PubMed ID: 9495830
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutations in conserved regions 1, 2, and 3 of Raf-1 that activate transforming activity.
    Chan EY; Stang SL; Bottorff DA; Stone JC
    Mol Carcinog; 2002 Apr; 33(4):189-97. PubMed ID: 11933072
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identifying specific kinase substrates through engineered kinases and ATP analogs.
    Kumar NV; Eblen ST; Weber MJ
    Methods; 2004 Apr; 32(4):389-97. PubMed ID: 15003601
    [TBL] [Abstract][Full Text] [Related]  

  • 7. PAK1 primes MEK1 for phosphorylation by Raf-1 kinase during cross-cascade activation of the ERK pathway.
    Coles LC; Shaw PE
    Oncogene; 2002 Mar; 21(14):2236-44. PubMed ID: 11948406
    [TBL] [Abstract][Full Text] [Related]  

  • 8. MEK-2, a Caenorhabditis elegans MAP kinase kinase, functions in Ras-mediated vulval induction and other developmental events.
    Wu Y; Han M; Guan KL
    Genes Dev; 1995 Mar; 9(6):742-55. PubMed ID: 7729690
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interferon-alpha2b reduces phosphorylation and activity of MEK and ERK through a Ras/Raf-independent mechanism.
    Romerio F; Riva A; Zella D
    Br J Cancer; 2000 Aug; 83(4):532-8. PubMed ID: 10945503
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The RKIP (Raf-1 Kinase Inhibitor Protein) conserved pocket binds to the phosphorylated N-region of Raf-1 and inhibits the Raf-1-mediated activated phosphorylation of MEK.
    Rath O; Park S; Tang HH; Banfield MJ; Brady RL; Lee YC; Dignam JD; Sedivy JM; Kolch W; Yeung KC
    Cell Signal; 2008 May; 20(5):935-41. PubMed ID: 18294816
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ras binding opens c-Raf to expose the docking site for mitogen-activated protein kinase kinase.
    Terai K; Matsuda M
    EMBO Rep; 2005 Mar; 6(3):251-5. PubMed ID: 15711535
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of Raf-1 S471 as a novel phosphorylation site critical for Raf-1 and B-Raf kinase activities and for MEK binding.
    Zhu J; Balan V; Bronisz A; Balan K; Sun H; Leicht DT; Luo Z; Qin J; Avruch J; Tzivion G
    Mol Biol Cell; 2005 Oct; 16(10):4733-44. PubMed ID: 16093354
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Radicicol suppresses transformation and restores tropomyosin-2 expression in both ras- and MEK-transformed cells without inhibiting the Raf/MEK/ERK signaling cascade.
    Kim PN; Jonasch E; Mosterman BC; Mier JW; Janssen RA
    Cell Growth Differ; 2001 Nov; 12(11):543-50. PubMed ID: 11714635
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel C-Raf phosphorylation sites: serine 296 and 301 participate in Raf regulation.
    Hekman M; Fischer A; Wennogle LP; Wang YK; Campbell SL; Rapp UR
    FEBS Lett; 2005 Jan; 579(2):464-8. PubMed ID: 15642359
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338.
    King AJ; Sun H; Diaz B; Barnard D; Miao W; Bagrodia S; Marshall MS
    Nature; 1998 Nov; 396(6707):180-3. PubMed ID: 9823899
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of novel substrates of MAP Kinase cascades using bioengineered kinases that uniquely utilize analogs of ATP to phosphorylate substrates.
    Zheng H; Al-Ayoubi A; Eblen ST
    Methods Mol Biol; 2010; 661():167-83. PubMed ID: 20811983
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions.
    Kolch W
    Biochem J; 2000 Oct; 351 Pt 2(Pt 2):289-305. PubMed ID: 11023813
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A Raf-induced, MEK-independent signaling pathway regulates atrial natriuretic factor gene expression in cardiac muscle cells.
    Jette C; Thorburn A
    FEBS Lett; 2000 Feb; 467(1):1-6. PubMed ID: 10664445
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation of (His)6-Raf-1 in vitro by partially purified plasma membranes from v-Ras-transformed and serum-stimulated fibroblasts.
    Dent P; Sturgill TW
    Proc Natl Acad Sci U S A; 1994 Sep; 91(20):9544-8. PubMed ID: 7937802
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of novel in vivo Raf-1 phosphorylation sites mediating positive feedback Raf-1 regulation by extracellular signal-regulated kinase.
    Balan V; Leicht DT; Zhu J; Balan K; Kaplun A; Singh-Gupta V; Qin J; Ruan H; Comb MJ; Tzivion G
    Mol Biol Cell; 2006 Mar; 17(3):1141-53. PubMed ID: 16407412
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.