135 related articles for article (PubMed ID: 14711815)
1. Evidence supporting a role for calcium in apoptosis induction by the synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO).
Hail N; Konopleva M; Sporn M; Lotan R; Andreeff M
J Biol Chem; 2004 Mar; 279(12):11179-87. PubMed ID: 14711815
[TBL] [Abstract][Full Text] [Related]
2. The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces caspase-dependent and -independent apoptosis in acute myelogenous leukemia.
Konopleva M; Tsao T; Estrov Z; Lee RM; Wang RY; Jackson CE; McQueen T; Monaco G; Munsell M; Belmont J; Kantarjian H; Sporn MB; Andreeff M
Cancer Res; 2004 Nov; 64(21):7927-35. PubMed ID: 15520199
[TBL] [Abstract][Full Text] [Related]
3. Induction of redox imbalance and apoptosis in multiple myeloma cells by the novel triterpenoid 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid.
Ikeda T; Nakata Y; Kimura F; Sato K; Anderson K; Motoyoshi K; Sporn M; Kufe D
Mol Cancer Ther; 2004 Jan; 3(1):39-45. PubMed ID: 14749474
[TBL] [Abstract][Full Text] [Related]
4. The novel triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO) potently enhances apoptosis induced by tumor necrosis factor in human leukemia cells.
Stadheim TA; Suh N; Ganju N; Sporn MB; Eastman A
J Biol Chem; 2002 May; 277(19):16448-55. PubMed ID: 11880365
[TBL] [Abstract][Full Text] [Related]
5. Activation of peroxisome proliferator-activated receptor gamma by a novel synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces growth arrest and apoptosis in breast cancer cells.
Lapillonne H; Konopleva M; Tsao T; Gold D; McQueen T; Sutherland RL; Madden T; Andreeff M
Cancer Res; 2003 Sep; 63(18):5926-39. PubMed ID: 14522919
[TBL] [Abstract][Full Text] [Related]
6. Ca2+ influx-mediated dilation of the endoplasmic reticulum and c-FLIPL downregulation trigger CDDO-Me-induced apoptosis in breast cancer cells.
Jeong SA; Kim IY; Lee AR; Yoon MJ; Cho H; Lee JS; Choi KS
Oncotarget; 2015 Aug; 6(25):21173-92. PubMed ID: 26053096
[TBL] [Abstract][Full Text] [Related]
7. Apoptotic activity and mechanism of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic-acid and related synthetic triterpenoids in prostate cancer.
Hyer ML; Shi R; Krajewska M; Meyer C; Lebedeva IV; Fisher PB; Reed JC
Cancer Res; 2008 Apr; 68(8):2927-33. PubMed ID: 18413762
[TBL] [Abstract][Full Text] [Related]
8. 2-Cyano-3,12-dioxooleana-1,9-dien-28-imidazolide (CDDO-Im) directly targets mitochondrial glutathione to induce apoptosis in pancreatic cancer.
Samudio I; Konopleva M; Hail N; Shi YX; McQueen T; Hsu T; Evans R; Honda T; Gribble GW; Sporn M; Gilbert HF; Safe S; Andreeff M
J Biol Chem; 2005 Oct; 280(43):36273-82. PubMed ID: 16118208
[TBL] [Abstract][Full Text] [Related]
9. Depletion of intracellular glutathione contributes to JNK-mediated death receptor 5 upregulation and apoptosis induction by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me).
Yue P; Zhou Z; Khuri FR; Sun SY
Cancer Biol Ther; 2006 May; 5(5):492-7. PubMed ID: 16582599
[TBL] [Abstract][Full Text] [Related]
10. Identification of a novel synthetic triterpenoid, methyl-2-cyano-3,12-dioxooleana-1,9-dien-28-oate, that potently induces caspase-mediated apoptosis in human lung cancer cells.
Kim KB; Lotan R; Yue P; Sporn MB; Suh N; Gribble GW; Honda T; Wu GS; Hong WK; Sun SY
Mol Cancer Ther; 2002 Jan; 1(3):177-84. PubMed ID: 12467212
[TBL] [Abstract][Full Text] [Related]
11. c-FLIP downregulation contributes to apoptosis induction by the novel synthetic triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me) in human lung cancer cells.
Zou W; Chen S; Liu X; Yue P; Sporn MB; Khuri FR; Sun SY
Cancer Biol Ther; 2007 Oct; 6(10):1614-20. PubMed ID: 18253090
[TBL] [Abstract][Full Text] [Related]
12. Synthetic triterpenoids inhibit growth and induce apoptosis in human glioblastoma and neuroblastoma cells through inhibition of prosurvival Akt, NF-kappaB and Notch1 signaling.
Gao X; Deeb D; Jiang H; Liu Y; Dulchavsky SA; Gautam SC
J Neurooncol; 2007 Sep; 84(2):147-57. PubMed ID: 17361329
[TBL] [Abstract][Full Text] [Related]
13. The novel triterpenoid CDDO and its derivatives induce apoptosis by disruption of intracellular redox balance.
Ikeda T; Sporn M; Honda T; Gribble GW; Kufe D
Cancer Res; 2003 Sep; 63(17):5551-8. PubMed ID: 14500394
[TBL] [Abstract][Full Text] [Related]
14. The novel triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO) induces apoptosis of human diffuse large B-cell lymphoma cells through a peroxisome proliferator-activated receptor gamma-independent pathway.
Ray DM; Morse KM; Hilchey SP; Garcia TM; Felgar RE; Maggirwar SB; Phipps RP; Bernstein SH
Exp Hematol; 2006 Sep; 34(9):1202-11. PubMed ID: 16939813
[TBL] [Abstract][Full Text] [Related]
15. The novel synthetic oleanane triterpenoid CDDO (2-cyano-3, 12-dioxoolean-1, 9-dien-28-oic acid) induces apoptosis in Mycosis fungoides/Sézary syndrome cells.
Zhang C; Ni X; Konopleva M; Andreeff M; Duvic M
J Invest Dermatol; 2004 Aug; 123(2):380-7. PubMed ID: 15245439
[TBL] [Abstract][Full Text] [Related]
16. The novel triterpenoid 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid induces apoptosis of human myeloid leukemia cells by a caspase-8-dependent mechanism.
Ito Y; Pandey P; Place A; Sporn MB; Gribble GW; Honda T; Kharbanda S; Kufe D
Cell Growth Differ; 2000 May; 11(5):261-7. PubMed ID: 10845427
[TBL] [Abstract][Full Text] [Related]
17. CDDO-imidazolide induces DNA damage, G2/M arrest and apoptosis in BRCA1-mutated breast cancer cells.
Kim EH; Deng CX; Sporn MB; Liby KT
Cancer Prev Res (Phila); 2011 Mar; 4(3):425-34. PubMed ID: 21372041
[TBL] [Abstract][Full Text] [Related]
18. The triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid and its derivatives elicit human lymphoid cell apoptosis through a novel pathway involving the unregulated mitochondrial permeability transition pore.
Brookes PS; Morse K; Ray D; Tompkins A; Young SM; Hilchey S; Salim S; Konopleva M; Andreeff M; Phipps R; Bernstein SH
Cancer Res; 2007 Feb; 67(4):1793-802. PubMed ID: 17308122
[TBL] [Abstract][Full Text] [Related]
19. The triterpenoid CDDO induces apoptosis in refractory CLL B cells.
Pedersen IM; Kitada S; Schimmer A; Kim Y; Zapata JM; Charboneau L; Rassenti L; Andreeff M; Bennett F; Sporn MB; Liotta LD; Kipps TJ; Reed JC
Blood; 2002 Oct; 100(8):2965-72. PubMed ID: 12351409
[TBL] [Abstract][Full Text] [Related]
20. 2-cyano-3,12-dioxooleana-1,9(11)-diene-28-oic acid disrupts microtubule polymerization: a possible mechanism contributing to apoptosis.
Couch RD; Ganem NJ; Zhou M; Popov VM; Honda T; Veenstra TD; Sporn MB; Anderson AC
Mol Pharmacol; 2006 Apr; 69(4):1158-65. PubMed ID: 16407469
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
