91 related articles for article (PubMed ID: 14715277)
1. siRNA-based inhibition specific for mutant SOD1 with single nucleotide alternation in familial ALS, compared with ribozyme and DNA enzyme.
Yokota T; Miyagishi M; Hino T; Matsumura R; Tasinato A; Urushitani M; Rao RV; Takahashi R; Bredesen DE; Taira K; Mizusawa H
Biochem Biophys Res Commun; 2004 Jan; 314(1):283-91. PubMed ID: 14715277
[TBL] [Abstract][Full Text] [Related]
2. [RNAi and neurological disease].
Yokota T
Rinsho Shinkeigaku; 2005 Nov; 45(11):973-5. PubMed ID: 16447777
[TBL] [Abstract][Full Text] [Related]
3. Selective silencing by RNAi of a dominant allele that causes amyotrophic lateral sclerosis.
Ding H; Schwarz DS; Keene A; Affar el B; Fenton L; Xia X; Shi Y; Zamore PD; Xu Z
Aging Cell; 2003 Aug; 2(4):209-17. PubMed ID: 12934714
[TBL] [Abstract][Full Text] [Related]
4. Transgenic small interfering RNA halts amyotrophic lateral sclerosis in a mouse model.
Saito Y; Yokota T; Mitani T; Ito K; Anzai M; Miyagishi M; Taira K; Mizusawa H
J Biol Chem; 2005 Dec; 280(52):42826-30. PubMed ID: 16221675
[TBL] [Abstract][Full Text] [Related]
5. Allele-specific RNAi selectively silences mutant SOD1 and achieves significant therapeutic benefit in vivo.
Xia X; Zhou H; Huang Y; Xu Z
Neurobiol Dis; 2006 Sep; 23(3):578-86. PubMed ID: 16857362
[TBL] [Abstract][Full Text] [Related]
6. Design of functional small interfering RNAs targeting amyotrophic lateral sclerosis-associated mutant alleles.
Geng CM; Ding HL
Chin Med J (Engl); 2011 Jan; 124(1):106-10. PubMed ID: 21362317
[TBL] [Abstract][Full Text] [Related]
7. An RNAi strategy for treatment of amyotrophic lateral sclerosis caused by mutant Cu,Zn superoxide dismutase.
Xia XG; Zhou H; Zhou S; Yu Y; Wu R; Xu Z
J Neurochem; 2005 Jan; 92(2):362-7. PubMed ID: 15663483
[TBL] [Abstract][Full Text] [Related]
8. Superoxide dismutase 1 mutants related to amyotrophic lateral sclerosis induce endoplasmic stress in neuro2a cells.
Oh YK; Shin KS; Yuan J; Kang SJ
J Neurochem; 2008 Feb; 104(4):993-1005. PubMed ID: 18233996
[TBL] [Abstract][Full Text] [Related]
9. RNA interference-mediated silencing of mutant superoxide dismutase rescues cyclosporin A-induced death in cultured neuroblastoma cells.
Maxwell MM; Pasinelli P; Kazantsev AG; Brown RH
Proc Natl Acad Sci U S A; 2004 Mar; 101(9):3178-83. PubMed ID: 14981234
[TBL] [Abstract][Full Text] [Related]
10. In vivo application of an RNAi strategy for the selective suppression of a mutant allele.
Kubodera T; Yamada H; Anzai M; Ohira S; Yokota S; Hirai Y; Mochizuki H; Shimada T; Mitani T; Mizusawa H; Yokota T
Hum Gene Ther; 2011 Jan; 22(1):27-34. PubMed ID: 20649474
[TBL] [Abstract][Full Text] [Related]
11. Mutant SOD1 mediated pathogenesis of Amyotrophic Lateral Sclerosis.
Kaur SJ; McKeown SR; Rashid S
Gene; 2016 Feb; 577(2):109-18. PubMed ID: 26657039
[TBL] [Abstract][Full Text] [Related]
12. Silencing strategies for therapy of SOD1-mediated ALS.
van Zundert B; Brown RH
Neurosci Lett; 2017 Jan; 636():32-39. PubMed ID: 27507699
[TBL] [Abstract][Full Text] [Related]
13. Therapeutic gene silencing delivered by a chemically modified small interfering RNA against mutant SOD1 slows amyotrophic lateral sclerosis progression.
Wang H; Ghosh A; Baigude H; Yang CS; Qiu L; Xia X; Zhou H; Rana TM; Xu Z
J Biol Chem; 2008 Jun; 283(23):15845-52. PubMed ID: 18367449
[TBL] [Abstract][Full Text] [Related]
14. Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosis.
Miller TM; Kim SH; Yamanaka K; Hester M; Umapathi P; Arnson H; Rizo L; Mendell JR; Gage FH; Cleveland DW; Kaspar BK
Proc Natl Acad Sci U S A; 2006 Dec; 103(51):19546-51. PubMed ID: 17164329
[TBL] [Abstract][Full Text] [Related]
15. Downregulation of Homer1b/c in SOD1 G93A Models of ALS: A Novel Mechanism of Neuroprotective Effect of Lithium and Valproic Acid.
Jiang HZ; Wang SY; Yin X; Jiang HQ; Wang XD; Wang J; Wang TH; Qi Y; Yang YQ; Wang Y; Zhang CT; Feng HL
Int J Mol Sci; 2016 Dec; 17(12):. PubMed ID: 27999308
[TBL] [Abstract][Full Text] [Related]
16. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1.
Jaarsma D; Haasdijk ED; Grashorn JA; Hawkins R; van Duijn W; Verspaget HW; London J; Holstege JC
Neurobiol Dis; 2000 Dec; 7(6 Pt B):623-43. PubMed ID: 11114261
[TBL] [Abstract][Full Text] [Related]
17. Progressive impairment of CaV1.1 function in the skeletal muscle of mice expressing a mutant type 1 Cu/Zn superoxide dismutase (G93A) linked to amyotrophic lateral sclerosis.
Beqollari D; Romberg CF; Dobrowolny G; Martini M; Voss AA; Musarò A; Bannister RA
Skelet Muscle; 2016; 6():24. PubMed ID: 27340545
[TBL] [Abstract][Full Text] [Related]
18. Therapeutic rAAVrh10 Mediated SOD1 Silencing in Adult SOD1(G93A) Mice and Nonhuman Primates.
Borel F; Gernoux G; Cardozo B; Metterville JP; Toro Cabrera GC; Song L; Su Q; Gao GP; Elmallah MK; Brown RH; Mueller C
Hum Gene Ther; 2016 Jan; 27(1):19-31. PubMed ID: 26710998
[TBL] [Abstract][Full Text] [Related]
19. Amyotrophic lateral sclerosis-related mutant superoxide dismutase 1 aggregates inhibit 14-3-3-mediated cell survival by sequestration into the JUNQ compartment.
Park JH; Jang HR; Lee IY; Oh HK; Choi EJ; Rhim H; Kang S
Hum Mol Genet; 2017 Sep; 26(18):3615-3629. PubMed ID: 28666328
[TBL] [Abstract][Full Text] [Related]
20. Knocking down metabotropic glutamate receptor 1 improves survival and disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis.
Milanese M; Giribaldi F; Melone M; Bonifacino T; Musante I; Carminati E; Rossi PI; Vergani L; Voci A; Conti F; Puliti A; Bonanno G
Neurobiol Dis; 2014 Apr; 64():48-59. PubMed ID: 24361555
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
