BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

400 related articles for article (PubMed ID: 14720319)

  • 1. Metabolic activation of polycyclic aromatic hydrocarbons to carcinogens by cytochromes P450 1A1 and 1B1.
    Shimada T; Fujii-Kuriyama Y
    Cancer Sci; 2004 Jan; 95(1):1-6. PubMed ID: 14720319
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Arylhydrocarbon receptor-dependent induction of liver and lung cytochromes P450 1A1, 1A2, and 1B1 by polycyclic aromatic hydrocarbons and polychlorinated biphenyls in genetically engineered C57BL/6J mice.
    Shimada T; Inoue K; Suzuki Y; Kawai T; Azuma E; Nakajima T; Shindo M; Kurose K; Sugie A; Yamagishi Y; Fujii-Kuriyama Y; Hashimoto M
    Carcinogenesis; 2002 Jul; 23(7):1199-207. PubMed ID: 12117779
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Metabolic activation of polycyclic aromatic hydrocarbons and other procarcinogens by cytochromes P450 1A1 and P450 1B1 allelic variants and other human cytochromes P450 in Salmonella typhimurium NM2009.
    Shimada T; Oda Y; Gillam EM; Guengerich FP; Inoue K
    Drug Metab Dispos; 2001 Sep; 29(9):1176-82. PubMed ID: 11502724
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of human cytochrome P450 1A1-, 1A2-, and 1B1-mediated activation of procarcinogens to genotoxic metabolites by polycyclic aromatic hydrocarbons.
    Shimada T; Guengerich FP
    Chem Res Toxicol; 2006 Feb; 19(2):288-94. PubMed ID: 16485905
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Polycyclic aromatic hydrocarbon-inducible DNA adducts: evidence by 32P-postlabeling and use of knockout mice for Ah receptor-independent mechanisms of metabolic activation in vivo.
    Kondraganti SR; Fernandez-Salguero P; Gonzalez FJ; Ramos KS; Jiang W; Moorthy B
    Int J Cancer; 2003 Jan; 103(1):5-11. PubMed ID: 12455047
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Induction of CYP1A1, CYP1A2, and CYP1B1 mRNAs by nitropolycyclic aromatic hydrocarbons in various human tissue-derived cells: chemical-, cytochrome P450 isoform-, and cell-specific differences.
    Iwanari M; Nakajima M; Kizu R; Hayakawa K; Yokoi T
    Arch Toxicol; 2002 Jun; 76(5-6):287-98. PubMed ID: 12107646
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The K-region trans-8,9-diol does not significantly contribute as an intermediate in the metabolic activation of dibenzo[a,l]pyrene to DNA-binding metabolites by human cytochrome P450 1A1 or 1B1.
    Luch A; Kishiyama S; Seidel A; Doehmer J; Greim H; Baird WM
    Cancer Res; 1999 Sep; 59(18):4603-9. PubMed ID: 10493514
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Xenobiotic-metabolizing enzymes involved in activation and detoxification of carcinogenic polycyclic aromatic hydrocarbons.
    Shimada T
    Drug Metab Pharmacokinet; 2006 Aug; 21(4):257-76. PubMed ID: 16946553
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dose-response studies on the induction of liver cytochromes P4501A1 and 1B1 by polycyclic aromatic hydrocarbons in arylhydrocarbon-responsive C57BL/6J mice.
    Shimada T; Sugie A; Yamada T; Kawazoe H; Hashimoto M; Azuma E; Nakajima T; Inoue K; Oda Y
    Xenobiotica; 2003 Sep; 33(9):957-71. PubMed ID: 14514444
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Tissue-specific induction of cytochromes P450 1A1 and 1B1 by polycyclic aromatic hydrocarbons and polychlorinated biphenyls in engineered C57BL/6J mice of arylhydrocarbon receptor gene.
    Shimada T; Sugie A; Shindo M; Nakajima T; Azuma E; Hashimoto M; Inoue K
    Toxicol Appl Pharmacol; 2003 Feb; 187(1):1-10. PubMed ID: 12628579
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Metabolic activation of polycyclic aromatic hydrocarbons and aryl and heterocyclic amines by human cytochromes P450 2A13 and 2A6.
    Shimada T; Murayama N; Yamazaki H; Tanaka K; Takenaka S; Komori M; Kim D; Guengerich FP
    Chem Res Toxicol; 2013 Apr; 26(4):529-37. PubMed ID: 23432465
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Metabolic activation of dibenzo[a,l]pyrene by human cytochrome P450 1A1 and P450 1B1 expressed in V79 Chinese hamster cells.
    Luch A; Schober W; Soballa VJ; Raab G; Greim H; Jacob J; Doehmer J; Seidel A
    Chem Res Toxicol; 1999 Apr; 12(4):353-64. PubMed ID: 10207125
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Docking and QSAR comparative studies of polycyclic aromatic hydrocarbons and other procarcinogen interactions with cytochromes P450 1A1 and 1B1.
    Gonzalez J; Marchand-Geneste N; Giraudel JL; Shimada T
    SAR QSAR Environ Res; 2012 Jan; 23(1-2):87-109. PubMed ID: 22150106
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Oral benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required for immune damage independent of total-body burden and clearance rate.
    Uno S; Dalton TP; Dragin N; Curran CP; Derkenne S; Miller ML; Shertzer HG; Gonzalez FJ; Nebert DW
    Mol Pharmacol; 2006 Apr; 69(4):1103-14. PubMed ID: 16377763
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Different mechanisms for inhibition of human cytochromes P450 1A1, 1A2, and 1B1 by polycyclic aromatic inhibitors.
    Shimada T; Murayama N; Okada K; Funae Y; Yamazaki H; Guengerich FP
    Chem Res Toxicol; 2007 Mar; 20(3):489-96. PubMed ID: 17291012
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Urban dust particulate matter alters PAH-induced carcinogenesis by inhibition of CYP1A1 and CYP1B1.
    Courter LA; Musafia-Jeknic T; Fischer K; Bildfell R; Giovanini J; Pereira C; Baird WM
    Toxicol Sci; 2007 Jan; 95(1):63-73. PubMed ID: 17060372
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Role of cytochrome p4501 family members in the metabolic activation of polycyclic aromatic hydrocarbons in mouse epidermis.
    Kleiner HE; Vulimiri SV; Hatten WB; Reed MJ; Nebert DW; Jefcoate CR; DiGiovanni J
    Chem Res Toxicol; 2004 Dec; 17(12):1667-74. PubMed ID: 15606143
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Carcinogenic polycyclic aromatic hydrocarbons induce CYP1A1 in human cells via a p53-dependent mechanism.
    Wohak LE; Krais AM; Kucab JE; Stertmann J; Øvrebø S; Seidel A; Phillips DH; Arlt VM
    Arch Toxicol; 2016 Feb; 90(2):291-304. PubMed ID: 25398514
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tissue specific induction of cytochrome P450 (CYP) 1A1 and 1B1 in rat liver and lung following in vitro (tissue slice) and in vivo exposure to benzo(a)pyrene.
    Harrigan JA; McGarrigle BP; Sutter TR; Olson JR
    Toxicol In Vitro; 2006 Jun; 20(4):426-38. PubMed ID: 16198082
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The resveratrol analogue, 2,3',4,5'-tetramethoxystilbene, does not inhibit CYP gene expression, enzyme activity and benzo[a]pyrene-DNA adduct formation in MCF-7 cells exposed to benzo[a]pyrene.
    Einem Lindeman T; Poirier MC; Divi RL
    Mutagenesis; 2011 Sep; 26(5):629-35. PubMed ID: 21669939
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.