BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 14722157)

  • 1. A phosphorylated, carboxy-terminal fragment of beta-amyloid precursor protein localizes to the splicing factor compartment.
    Muresan Z; Muresan V
    Hum Mol Genet; 2004 Mar; 13(5):475-88. PubMed ID: 14722157
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Phosphorylation of amyloid precursor carboxy-terminal fragments enhances their processing by a gamma-secretase-dependent mechanism.
    Vingtdeux V; Hamdane M; Gompel M; Bégard S; Drobecq H; Ghestem A; Grosjean ME; Kostanjevecki V; Grognet P; Vanmechelen E; Buée L; Delacourte A; Sergeant N
    Neurobiol Dis; 2005 Nov; 20(2):625-37. PubMed ID: 15936948
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Frame-shifted amyloid precursor protein found in Alzheimer's disease and Down's syndrome increases levels of secreted amyloid beta40.
    van Dijk R; Fischer DF; Sluijs JA; Sonnemans MA; Hobo B; Mercken L; Mann DM; Hol EM; van Leeuwen FW
    J Neurochem; 2004 Aug; 90(3):712-23. PubMed ID: 15255950
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of APP phosphorylation in FE65-dependent gene transactivation mediated by AICD.
    Nakaya T; Suzuki T
    Genes Cells; 2006 Jun; 11(6):633-45. PubMed ID: 16716194
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Fibrillar prion peptide PrP(106-126) treatment induces Dab1 phosphorylation and impairs APP processing and Abeta production in cortical neurons.
    Gavín R; Ureña J; Rangel A; Pastrana MA; Requena JR; Soriano E; Aguzzi A; Del Río JA
    Neurobiol Dis; 2008 May; 30(2):243-54. PubMed ID: 18374587
    [TBL] [Abstract][Full Text] [Related]  

  • 6. LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease.
    Majercak J; Ray WJ; Espeseth A; Simon A; Shi XP; Wolffe C; Getty K; Marine S; Stec E; Ferrer M; Strulovici B; Bartz S; Gates A; Xu M; Huang Q; Ma L; Shughrue P; Burchard J; Colussi D; Pietrak B; Kahana J; Beher D; Rosahl T; Shearman M; Hazuda D; Sachs AB; Koblan KS; Seabrook GR; Stone DJ
    Proc Natl Acad Sci U S A; 2006 Nov; 103(47):17967-72. PubMed ID: 17098871
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rac1 inhibition negatively regulates transcriptional activity of the amyloid precursor protein gene.
    Wang PL; Niidome T; Akaike A; Kihara T; Sugimoto H
    J Neurosci Res; 2009 Jul; 87(9):2105-14. PubMed ID: 19267423
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Presenilin-1-mediated retention of APP derivatives in early biosynthetic compartments.
    Réchards M; Xia W; Oorschot V; van Dijk S; Annaert W; Selkoe DJ; Klumperman J
    Traffic; 2006 Mar; 7(3):354-64. PubMed ID: 16497228
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Swedish amyloid precursor protein mutation increases phosphorylation of eIF2alpha in vitro and in vivo.
    Kim HS; Choi Y; Shin KY; Joo Y; Lee YK; Jung SY; Suh YH; Kim JH
    J Neurosci Res; 2007 May; 85(7):1528-37. PubMed ID: 17393484
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Amyloid precursor protein cytoplasmic domain with phospho-Thr668 accumulates in Alzheimer's disease and its transgenic models: a role to mediate interaction of Abeta and tau.
    Shin RW; Ogino K; Shimabuku A; Taki T; Nakashima H; Ishihara T; Kitamoto T
    Acta Neuropathol; 2007 Jun; 113(6):627-36. PubMed ID: 17431643
    [TBL] [Abstract][Full Text] [Related]  

  • 11. IGF-1 promotes beta-amyloid production by a secretase-independent mechanism.
    Araki W; Kume H; Oda A; Tamaoka A; Kametani F
    Biochem Biophys Res Commun; 2009 Feb; 380(1):111-4. PubMed ID: 19167357
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Intracellular copper deficiency increases amyloid-beta secretion by diverse mechanisms.
    Cater MA; McInnes KT; Li QX; Volitakis I; La Fontaine S; Mercer JF; Bush AI
    Biochem J; 2008 May; 412(1):141-52. PubMed ID: 18248325
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.
    Haass C; Koo EH; Mellon A; Hung AY; Selkoe DJ
    Nature; 1992 Jun; 357(6378):500-3. PubMed ID: 1608449
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer's disease.
    Ryoo SR; Cho HJ; Lee HW; Jeong HK; Radnaabazar C; Kim YS; Kim MJ; Son MY; Seo H; Chung SH; Song WJ
    J Neurochem; 2008 Mar; 104(5):1333-44. PubMed ID: 18005339
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phosphorylation of the cytoplasmic domain of Alzheimer's beta-amyloid precursor protein at Ser655 by a novel protein kinase.
    Isohara T; Horiuchi A; Watanabe T; Ando K; Czernik AJ; Uno I; Greengard P; Nairn AC; Suzuki T
    Biochem Biophys Res Commun; 1999 May; 258(2):300-5. PubMed ID: 10329382
    [TBL] [Abstract][Full Text] [Related]  

  • 16. BACE inhibitor reduces APP-beta-C-terminal fragment accumulation in axonal swellings of okadaic acid-induced neurodegeneration.
    Yoon SY; Choi JE; Yoon JH; Huh JW; Kim DH
    Neurobiol Dis; 2006 May; 22(2):435-44. PubMed ID: 16480887
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mutations in amyloid precursor protein and presenilin-1 genes increase the basal oxidative stress in murine neuronal cells and lead to increased sensitivity to oxidative stress mediated by amyloid beta-peptide (1-42), HO and kainic acid: implications for Alzheimer's disease.
    Mohmmad Abdul H; Sultana R; Keller JN; St Clair DK; Markesbery WR; Butterfield DA
    J Neurochem; 2006 Mar; 96(5):1322-35. PubMed ID: 16478525
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Palmitic acid-treated astrocytes induce BACE1 upregulation and accumulation of C-terminal fragment of APP in primary cortical neurons.
    Patil S; Sheng L; Masserang A; Chan C
    Neurosci Lett; 2006 Oct; 406(1-2):55-9. PubMed ID: 16904262
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Phosphorylated tau in neuritic plaques of APP(sw)/Tau (vlw) transgenic mice and Alzheimer disease.
    Pérez M; Morán MA; Ferrer I; Avila J; Gómez-Ramos P
    Acta Neuropathol; 2008 Oct; 116(4):409-18. PubMed ID: 18679696
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Syntaxin 5 interacts specifically with presenilin holoproteins and affects processing of betaAPP in neuronal cells.
    Suga K; Saito A; Tomiyama T; Mori H; Akagawa K
    J Neurochem; 2005 Jul; 94(2):425-39. PubMed ID: 15998293
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.